LAB-Secretome DB


LAB-Secretome DB A comparative analysis of the predicted secretomes of Lactic Acid Bacteria

Protein with distant homolog in non-LAB species

GI:29377331
NCBI info	29377331	Gene:	-	Synonym:	EF2863
SCL:	@Secretory(released) (with CS)	Length	314	COG	COG3325G
Species:	Enterococcus_faecalis_V583	Location	2745480..2746424	Strand:	+
Product:	endo-beta-N-acetylglucosaminidase
Sequence:	MGHQLSTHFFNKKTGIISTFLSLILLVGGLLFALPAFEVQAASTVTPKTVMYVEVNNHDFNNVGKYTLAGTNQPAFDMGIIFAANINYDTVNKKPYLYLN ERVQQTLNEAETQIRPVQARGTKVLLSILGNHEGAGFANFPTYESADAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNGTPQPNNSSFIWLLQALRNRLGN DKLITFYNIGPAAANSSANPQMSSLIDYAWNPYYSTWNPPQIAGMPASRLGASAVEVGVNQNLAAQYAKRTKAEQYGIYLMYNLPGKDSSAYISAATQEL YGRKTNYSPTVPTP

Protein Domain structure of 29377331 (Scale up the web page to see more details)

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Distant Homologs of 29377331 in the non-LAB species

Alignment	GI	Species	Product	Length	Eval	Identities	Positives
Show aligned area	50842474	Propionibacterium acnes KPA171202	endo-beta-N-acetylglucosaminidase H	302	7e-74	0.48	0.65
HFFNKKTGIISTFLSLILLVGGLLFALPAFEVQAASTVTPKTVMYVEVNNHDFNNVGKYTLAGTNQPAFDMGIIFAANINYDTVNKKPYLYLNERVQQTL H G++ST L G+ FA P +A+ VT T +Y+EVN+ D VG + G ++P FD+ +IFAANINYD YL+LNERV +TL HVLASTVGVVSTALITAQTPAGIAFARPR---RASRAVT--TAVYIEVNHEDLATVGAFVREGVHRPVFDLAMIFAANINYDGCTA--YLHLNERVMETL NEAETQIRPVQARGTKVLLSILGNHEGAGFANFPTYESADAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNGTPQPNNSSFIWLLQALRNRLGNDKLITFY AETQIRP+Q RGTKVLLS+LGNHEGAGFANFPT AD FAAQ+ VV+ YHLDG+D DDEY+EYGKNGT QPN F+W ++ALR LG KL+T Y RAAETQIRPLQRRGTKVLLSLLGNHEGAGFANFPTRHDADRFAAQVASVVHRYHLDGVDLDDEYSEYGKNGTGQPNEDFFVWFVRALRRHLGPHKLLTLY NIGPAAANS-SANPQMSSLIDYAWNPYYSTWNPPQIAGMPASRLGASAVEVG-VNQNLAAQYAKRTKAEQYGIYLMYNLPGKDSSAYISAATQELYGRK +IGP+ + S+ S +DYAWNP+Y T+ P + GMP S +GA+AV+ G + + A +T + YG+++ Y+L + + + A T L GR+ SIGPSVNRTVSSAGNASDDLDYAWNPWYGTYQEPSVLGMPRSHVGAAAVDWGHTSIEMIQTMASQTIHDGYGVFMTYDLRVSTNPSLVQAMTTALEGRR
Show aligned area	21225894	Streptomyces coelicolor A3(2)	secreted endo-beta-N-acetylglucosaminidase	309	6e-73	0.56	0.71
PKTVMYVEVNNHDFNNVGKYTLAGTNQPAFDMGIIFAANINYDTVNKKPYLYLNERVQQTLNEAETQIRPVQARGTKVLLSILGNHEGAGFANFPTYESA P +V Y+EVNN+ N GKYTLA FD+ +IFAANINYDT K YL+ NE VQ+ L+ A TQIRP+Q +G KV+LS+LGNH+GAGFANFP+ ++A PTSVAYIEVNNNSMLNAGKYTLADGGGNVFDVAVIFAANINYDTGTKSAYLHFNENVQRVLDNAATQIRPLQQKGIKVVLSVLGNHQGAGFANFPSQQAA DAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNGTPQPNNSSFIWLLQALRNRLGNDKLITFYNIGPAAAN-SSANPQMSSLIDYAWNPYYSTWNPPQIAGM AFA QL V Y LDGIDFDDEYAEYG NGT QPN+SSF+ L+ ALR + DK+I+ YNIGPAA+ S +S+ DYAWNPYY TW P IA + SAFARQLSDAVAEYGLDGIDFDDEYAEYGNNGTAQPNDSSFVHLVTALRANM-PDKIISLYNIGPAASRLSYGGVDVSTDFDYAWNPYYGTWQVPGIA-L PASRLGASAVEVG-VNQNLAAQYAKRTKAEQYGIYLMYNLPGKDSSAYISAATQELYGRKTNYSP P S+L +AVE+G +Q+ +A+ A+RT YG+YL YNL G D SA +SA T+ELYG + +P PQSKLSPAAVEIGRTSQSTSAELARRTVDGGYGVYLTYNLDGSDRSADVSAFTRELYGSEAVRTP
Show aligned area	163840290	Renibacterium salmoninarum ATCC 33209	endo-beta-N-acetylglucosaminidase H precursor	278	2e-55	0.53	0.69
PKTVMYVEVNNHDFNNVGKYTLAGTNQPAFDMGIIFAANINYDTVNKKPYLYLNERVQQTLNEAETQIRPVQARGTKVLLSILGNHEGAGFANFPTYESA P +V+Y+EVN++ N GKYTL+ FD+ +IFAANINYDT YL+ N++V LN+AE QI+P+Q +G KVLLS+LG H+GAGF NFP SA PTSVVYIEVNSNSMLNAGKYTLSTGGAQVFDIAVIFAANINYDTSTNSAYLHFNDQVTAVLNDAENQIKPLQDKGIKVLLSVLGTHQGAGFTNFPDKASA DAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNGTPQPNNSSFIWLLQALRNRLGNDKLITFYNIGPAAANSSAN-PQMSSLIDYAWNPYYSTWNPPQIAGM +AFAA+L V Y LDGIDFDDEY EYG NGT PN+SSF +L+ ALR++LG+ KLIT Y+IGP+A S N ++ +Y+WNPYY TW+ P+ EAFAAELSNAVTQYGLDGIDFDDEYTEYGNNGTGDPNDSSFYYLVTALRHKLGSSKLITLYDIGPSAERMSYNGNSIADTFNYSWNPYYGTWSDPR---G PASRLGASAVEVGVN P+S+ S V +N PSSKSKRSPAAVQIN
Show aligned area	29346695	Bacteroides thetaiotaomicron VPI-5482	endo-beta-N-acetylglucosaminidase	306	6e-28	0.33	0.52
EVQAASTVTPKTVMYVEVNNHDFNNVGKYTLAGTNQPAFDMGIIFAANINYDTVNKKPYLYLNERVQQTLNEAETQIRPVQARGTKVLLSILGNHEGAGF EV S K ++Y+EVN+ + N G Y + + P FD I+FAANI V LY N VQ L+ +T I+P+Q +G KVLL +LG+H G GF EVVTRSATGIKNIVYIEVNDINPLNAGSYIM--DDAPFFDYVILFAANIR--GVGSDATLYNNPNVQYILDHKDTLIKPLQDKGIKVLLGLLGDHTGLGF ANFPTYESADAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNGTPQPNNSSFIWLLQALRNRLGNDKLITFYNIGPAAANSSANPQMSSLIDYAWNPYYSTW AN + ++ + FA + V+ Y LDG+DFDDE+AEYG+NG P + SF L+ AL N++ K IT +N G + + N S IDY ++++ ANMNSAQT-EQFATAVANAVSQYGLDGVDFDDEWAEYGRNGYPSGSTGSFSNLITALHNKMPG-KTITVFNYGYTSELTGVN----SYIDYGIYAFFNSP NPPQIAGMPASRLGASAVEVGVNQNLAAQ--YAKRTKAEQYGIYLMYNLPGKDSSAYISAATQELYGRKTNY + GMP S+ + + + A+ Y+ + ++ YG Y+L + + ++ + + Y SWSTGFGMPNSKFAPYTINLNSAPSAASAQLYSGQVASKGYGAIGYYDLRANNIVSVLNGVAKGAFKSTCTY
Show aligned area	29349395	Bacteroides thetaiotaomicron VPI-5482	endo-beta-N-acetylglucosaminidase F1 precursor	476	1e-15	0.28	0.48
MYVEVNNHDFNNVGKYTLAGTNQPAFDMGIIFAANINYDTVNKKPYLYLNERVQQTLNEAETQIRPVQARGTKVLLSILGNHEGAGFANFPTYESADAFA ++ EVN+ + N + L + +D+ ++FAANINYD +P + N VQ L+ ET ++P++ RG KVLL +LGNH+ G A + + A FA LFFEVNDVNPLNTLSFQLE-NGKLLWDVVVLFAANINYDAEAGRPRVQCNPNVQYLLDNNETLLQPLRRRGVKVLLGLLGNHDITGLAQL-SEQGAKDFA AQLEQVVNTYHLDGIDFDDEYAEYGKNGTP---QPNNSSFIWLLQALRNRLGNDKLITFYNIGPAAANSSANP-QMSSLIDYAWNPYYSTWNPPQIAGMP ++ Q Y+LDG+++DDEY+ P P+ ++ L + + DKL+T ++ G ++ + ID Y S P I M REVAQYCKAYNLDGVNYDDEYSNSPDLSNPSLTNPSTAAAARLCYETKQAM-PDKLVTVFDWGQMYGVATVDGVDAKEWIDIVVANYGSAAYP--IGQMT ASRLGASAVE--VGVNQNLAAQYAKRTKAEQYGIYLMYN-LPGKDSSAY--ISAATQELYGRKTNYSPTV------PTP + ++E +G +L+A A+ YG ++ + P K S + + + LYG +PT+ PTP KKQCSGISMEFNLGGGGSLSASKAQSMIDGGYGWFMGFAPSPAKYGSVFSRLQGGGEVLYGSNVA-APTIFYKKNDPTP
Show aligned area	37526176	Photorhabdus luminescens subsp. laumondii TTO1	hypothetical protein plu2263	303	7e-14	0.35	0.58
NVGKYTLAGTNQPAFDMGIIFAANINYDTVNKKPYLYLNERVQQTLNEAETQIRPVQARGTKVLLSILGNHEGAGFANFPTYESADAFAAQLEQVVNTYH ++G + + T +P F I+FAANIN ++++ P L+ N+++ L E + +R +Q +G +V LS LGNH+ AG++ + +A A ++ V Y DIGNFVVKQTEKPFFSDVILFAANIN-NSISNSPVLFYNDKISSILKENISLVRNLQKKGIRVQLSYLGNHQNAGWSCNMSQATATKLANEMVNDVVKYG LDGIDFDDEYAE-YGKNGTPQPNNSSFIWLLQALRN LDGI+ DDEY+ YG N SF W+ A+++ LDGINIDDEYSTCYG-------NRQSFYWVADAIKS
Show aligned area	29346694	Bacteroides thetaiotaomicron VPI-5482	putative endo-beta-N-acetylglucosaminidase F1 precursor (mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F1)	508	3e-13	0.30	0.50
NINYDTV----NKKPYLYLNERVQQTLNEAETQIRPVQARGTKVLLSILGNHEGAGFANFPTYESADAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNGTP N+ + TV N P LYL + + L + E I P+Q KV L+I G EG GF+N E F +++Q+++ YHLDG++ D Y ++ NLQFATVKADDNLLPSLYLKDDLAYVLKKREKYIVPLQQLDHKVCLAIKGAGEGIGFSNLGEKEMM-IFVERIKQMIDIYHLDGVNLYDANFSYEESNEN QPNNSSFIWLLQALRNRLGNDKLITFYNI--GPAAANSSANPQMSSLIDYAW----NPYYSTWNPPQ-----IAGMPASRLGASAVEVGVNQNLA +++ + +LR++LGN K+IT+ P + AN ++ L+DYAW N W+ P+ IAG+ + GA ++ ++ A INYSNNLCKFVASLRDKLGN-KIITYTQTSESPEGITNDANLKLGELLDYAWCDQLNTIIDPWSTPEKWTRPIAGLNKEKWGALNTDIHMSSEQA
Show aligned area	126699037	Clostridium difficile 630	putative bifunctional protein: peroxiredoxin/chitinase	712	4e-05	0.37	0.57
KVLLSILGNHEGAGFANFP-TYESADAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNG-TPQPNN-SSFIWLLQALRNRLGNDKLITFYNIGPAA-ANSSA KV+++I G GF++ T S FA Q+ Q++N Y LDGID D EY +G T +P + +F LL A+R+ +G+DK ++ G NSSA KVIVAI-GGWGAEGFSDAALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIRDVIGDDKWLSVAGTGDRGYINSSA N-PQMSSLIDY +++ +IDY EIDKIAPIIDY
Show aligned area	150003841	Bacteroides vulgatus ATCC 8482	glycoside hydrolase family protein	345	4e-04	0.37	0.56
KVLLSILGNHEGAGFANFPTYESAD----AFAAQLEQVVNTYHLDGIDFDDEYAEYGKNG---TPQPNNSSFIWLLQALRNRLGNDKLIT KVLLS+ G G + F D AFAA ++V++ + LDGID D EY G G +P+ + +F L++ +R+ +G DKL+T KVLLSV----GGWGSSRFSEMAQTDSTRMAFAADCKRVIDQFDLDGIDIDWEYPGIGTAGVSFSPE-DTDNFSLLMKDIRHAIGKDKLLT
Show aligned area	157370965	Serratia proteamaculans 568	glycoside hydrolase family protein	426	4e-04	0.38	0.50
LYLNERVQQTLNEAETQIRPV---QARGTKVLLSILGNHEGAGFANFP-TYESADAFAAQLEQVVNTYHLDGIDFDDEYAEYGKNG--TPQP-NNSSFIW +YL+ +V A+ Q+ PV Q KVLLS+ G GF+ T ES F ++QV+ YHLDGID D EY G G QP + ++F IYLSPKVM-----ADLQLLPVLRKQNPELKVLLSV-GGWGARGFSGAAATAESRAVFIRSVQQVIKQYHLDGIDLDWEYPVNGAWGLVESQPADRANFTL LLQALRNRLGNDKLIT LL L L KL+T LLAELHKALDKGKLLT