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LAB-Secretome
A comparative analysis of the predicted secretomes of Lactic Acid Bacteria

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Summary of results
Ubiquitous LaCOGs
Niche specific LaCOGs
Species specific LaCOGs
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Niche specific clusters


Dairy LAB specific LaCOGs
LACOG Function Product
SCL Distribution
LaCOG00012 cell-wall
turnover
beta-lactamase class A N-terminally anchored S.thermophilus, L.lactis
LaCOG00374 transport amino acid (glutamine arginine)
ABC transporter substrate-binding protein
Lipid anchored S.thermophilus, L.lactis



Plant-associated LAB specific LaCOGs
LACOG Function Product SCL Distribution
LaCOG02879 unknown hypothetical protein N-terminally anchored L.plantarum, L.brevis, P.pentosaceus
LaCOG01618 enzyme cell surface hydrolase membrane-bound (putative) N-terminally anchored L.plantarum, L.brevis, P.pentosaceus
LaCOG02082 transport ABC-type oligopeptide transport system substrate-binding protein Lipid anchored L.plantarum, L.brevis, P.pentosaceus
LaCOG02848 Cell-wall turnover glycosyl hydrolase family 25 (putative) Secreted L.plantarum, L.brevis
LaCOG02741 transport ABC-type oligopeptide transport system substrate-binding protein N-terminally anchored L.plantarum, L.brevis
LaCOG02931 unknown hypothetical protein N-terminally anchored L.plantarum, L.brevis
LaCOG02762 unknown hypothetical protein Secreted L.plantarum, L.brevis
LaCOG02819 unknown hypothetical protein Secreted L.plantarum, L.brevis
LaCOG02936 unknown hypothetical protein Secreted L.plantarum, L.brevis
LaCOG02927 unknown hypothetical protein Secreted, LPxTG Cell-wall anchored L.plantarum, L.brevis
LaCOG02775 unknown hypothetical protein Secreted  LPxTG Cell-wall anchored L.plantarum, L.brevis
LaCOG03437 Cell-wall turnover gamma-D-glutamate-meso-diaminopimelate muropeptidase Secreted L.plantarum, L.brevis, P.pentosaceus


GI-tract LAB specific LaCOGs
LACOG Function Product SCL Distribution
LaCOG99375 unknown hypothetical protein N-terminally anchored L.reuteri, L.salivarius
LaCOG03292 enzyme glycerophosphoryl diester phosphodiesterase N-terminally anchored L.gasseri, L.johnsonii
LaCOG03247 signalling/
regulation
two-component system inducer peptide precursor Secreted via minor pathways L.gasseri, L.johnsonii
LaCOG03265 unknown hypothetical protein Lipid anchored L.gasseri, L.johnsonii
LaCOG03134 unknown hypothetical protein Lipid anchored L.gasseri, L.johnsonii
LaCOG90012 unknown hypothetical protein N-terminally anchored L.gasseri, L.johnsonii
LaCOG03230 unknown hypothetical protein N-terminally anchored L.gasseri, L.johnsonii
LaCOG03325 unknown hypothetical protein Secreted L.gasseri, L.johnsonii
LaCOG03334 unknown hypothetical protein Secreted L.gasseri, L.johnsonii
LaCOG03226 unknown hypothetical protein Secreted,  LPxTG Cell-wall anchored L.acidophilus, L.johnsonii
LaCOG03267 unknown hypothetical protein Secreted,  LPxTG Cell-wall anchored L.acidophilus, L.johnsonii
LaCOG90008 unknown hypothetical protein Lipid anchored L.gasseri, L.johnsonii, L.salivarius
LaCOG99312 unknown hypothetical protein variable L.acidophilus, L.salivarius
LaCOG99303 binding proteins hypothetical protein Secreted,  LPxTG Cell-wall anchored L.acidophilus, L.johnsonii
LaCOG02280 binding proteins mucus-binding protein (putative) Secreted,  LPxTG Cell-wall anchored L.acidophilus, L.gasseri, L.johnsonii
LaCOG02121 unknown hypothetical protein N-terminally anchored L.gasseri, L.johnsonii


L.acidophilus complex LAB specific LaCOGs
LACOG Function Product SCL Distribution
LaCOG90005 binding proteins agregation promoting protein Secreted L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus, L.gasseri, L.ohnsonii
LaCOG03110 competence
competence protein ComG N-terminally anchored L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus, L.gasseri, L.ohnsonii
LaCOG02167
unknown
hypothetical protein N-terminally anchored L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus, L.gasseri, L.ohnsonii
LaCOG02222 unknown hypothetical protein Secreted L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus, L.gasseri, L.ohnsonii
LaCOG99136 unknown hypothetical protein Lipid anchored L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus
LaCOG99319 unknown hypothetical protein N-terminally anchored L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus
LaCOG99305 unknown hypothetical protein secreted L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus
LaCOG99024 unknown hypothetical protein variable L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus
LaCOG90020 unknown hypothetical protein N-terminally anchored L.delbrueckii_bulgaricus, L.helveticus, L.ohnsonii
LaCOG99070 unknown hypothetical protein N-terminally anchored L.delbrueckii_bulgaricus, L.helveticus
LaCOG02218 unknown hypothetical protein variable L.delbrueckii_bulgaricus, L.acidophilus, L.gasseri, L.ohnsonii
LaCOG02187 unknown hypothetical protein N-terminally anchored L.delbrueckii_bulgaricus, L.gasseri, L.ohnsonii
LaCOG99095 unknown hypothetical protein N-terminally anchored L.delbrueckii_bulgaricus, L.acidophilus
LaCOG99373 unknown hypothetical protein N-terminally anchored L.delbrueckii_bulgaricus, L.helveticus, L.acidophilus
LaCOG99178 Cell-surface complex surface layer protein secreted L.delbrueckii_bulgaricus, L.helveticus
 
LaCOG02118 transport ABC-type phosphate/phosphonate transport system periplasmic component Lipid anchored L.helveticus, L.acidophilus, L.gasseri, L.ohnsonii
LaCOG03244 unknown hypothetical protein Lipid anchored L.helveticus, L.acidophilus, L.gasseri, L.ohnsonii
LaCOG99129 binding proteins fibronectin domain-containing protein N-terminally anchored L.helveticus, L.acidophiluss
LaCOG99251 Cell-surface complex surface layer protein secreted L.helveticus, L.acidophilus
LaCOG99100 Cell-surface complex surface layer protein secreted L.helveticus, L.acidophilus
LaCOG99174 Cell-surface complex surface layer protein secreted L.helveticus, L.acidophilus
LaCOG99068 Cell-surface complex surface layer protein secreted L.helveticus, L.acidophilus
LaCOG99046 Cell-surface complex surface layer protein secreted L.helveticus, L.acidophilus
LaCOG99186 enzyme metallo-aminopeptidase secreted L.helveticus, L.acidophilus
LaCOG99064 unknown hypothetical protein Lipid anchored L.helveticus, L.acidophilus
LaCOG99304 unknown hypothetical protein N-terminally anchored L.helveticus, L.acidophilus
LaCOG99210 unknown hypothetical protein secreted L.helveticus, L.acidophilus
LaCOG99164 unknown hypothetical protein secreted L.helveticus, L.acidophilus
LaCOG99144 unknown hypothetical protein secreted L.helveticus, L.acidophilus
LaCOG99006 unknown hypothetical protein Secreted  LPxTG Cell-wall anchored L.helveticus, L.acidophilus
LaCOG99031 unknown hypothetical protein secreted L.helveticus, L.acidophiluss
Copyright � 2010 Miaomiao Zhou
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