LAB-Secretome DB


LAB-Secretome DB A comparative analysis of the predicted secretomes of Lactic Acid Bacteria

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Summary of results

Ubiquitous LaCOGs

Niche specific LaCOGs

Species specific

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Protein with distant homolog in non-LAB species

GI:29376816
NCBI info	29376816	Gene:	-	Synonym:	EF2314
SCL:	@Multi-transmembrane	Length	745	COG	-
Species:	Enterococcus_faecalis_V583	Location	2236670..2237956	Strand:	-
Product:	bacteriocin, putative
Sequence:	MKTKRFQRTAAMLLCIFICAWTMFPLMGAAFAAENGLHDTAEPEITCFCDIHCTADALNADCPVCTQDVNACTGTEPEAPTETETPTEPEITCSCNIRCT ADTLNADCPVCTQDVAACTGAEPEIACFCDIRCTADTLNADCPICVQEAAACIGAEPEPVCTCETRCAADAPDTDCPICTQDVTGCTGKEPEPPAKLVCI CAAHCEPGAVNADCPACLLNLADCIVEAPTPVPVCVCENRCELGAVNADCPICRTDLAGCTGKAPAPIPASNLSIKITPPSGWATGSAAAEFRITDEAGN GFALVQVKIEKNGQWRDVTDSLKQNENRWYGEIDLSENCTVYVCANGHDGKVYEKSRYIECFDRTAPALRAGMDGRLLRAEASDDLSGVAAIYIDGEKYT DLTNGTLDIPLRDLPDDYEQLSVQAVDAAGNKSKIVQVKNPNYQAEDNKQKPSTGQTQPPATTAPVTSTTPAPTTPATSATTPPTTPTTNPATTTATKPA AGTGSAKPSASASAAPDEETDTTPRDPIPLTPDGQATVLDNATGEDGKEFYTIQTPDENVFYLIIDNQRDTENVYFLNAVTEADLMALAVKEDDTPQTDA IPDPEPACICTEQCAAGEVNTACPVCTLTRKDCTGKAPVTDTETEPDEKPEKTKSGGSGTLILVLLVALAAGGAGYYFKIYKPKKDLDDAEDFDELTGGD EEETVNEDEDVDAQEETRQTGDEEPAAYDEPEEPDYPENYGGEDD

Protein Domain structure of 29376816 (Scale up the web page to see more details)

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Distant Homologs of 29376816 in the non-LAB species

Alignment	GI	Species	Product	Length	Eval	Identities	Positives
Show aligned area	126698698	Clostridium difficile 630	hypothetical protein CD1107	244	9e-20	0.40	0.54
PAAGTGSAKPSASASAAPD-----EETDTTPRDPIPLTPDGQATVLDNATGEDGKEFYTIQTPDENVFYLIIDNQ-RDTENVYFLNAVTEADLMALAVKE PA G+A + A D EE + TP PLTP G AT++D+ G K+ T+ T N FY++ID D + V+FLN V EADLMAL PAYAQGAATEQPAGDATNDSNVVVEEKEETP----PLTPKGNATLVDDFGGN--KQLITVTTKSGNYFYILIDRAAEDEQTVHFLNQVDEADLMALTENG DDTPQTDAIPDPEPACICTEQCAAGEVNTACPVCTLTRKDCTGKAPVTDTETEPDEKPEKTKSGGSGTLILVLLVALAAGGAG-YYFKIYKPKKDLDDAE + +T+ C CTE+C AG++NT+CPVC + CTGK P T TE E+P K K G G ++ ++L AL GGA YYFK KPK+++ EAAKKTEI-------CNCTEKCEAGKINTSCPVCVTSMTGCTGKEP-TPAPTEQPEEP-KEKGGNPGVVLALVLFALLGGGAAFYYFKFMKPKQNVKGDT DFDELTGGDEEETVNEDE D ++ E E +EDE DLEDF----EFEDYDEDE
Show aligned area	219853579	Clostridium kluyveri NBRC 12016	hypothetical protein CKR_0236	225	3e-18	0.37	0.52
ATKPAAGTGSAKPSASASAAPDEETDTTPRDPIPLTPDGQATVLDNATGEDGKEFYTIQTPDENVFYLIIDNQRDTENVYFLNAVTEADLMALAVKEDDT +T A G P + + A E T P P TP G TV++ AT EDGK+FYTI TPDENVFYL+ID QR+ +NVYFLNAVTE DL+ALA K +DT STMAYASGGEETPEVTEAPATSETTSA----PNPFTPAGTGTVVNTATDEDGKQFYTITTPDENVFYLVIDLQREQDNVYFLNAVTEKDLLALAEKSEDT P--QTDAIPDPEPACICTEQCAAGEVNTACPVCTLTRKDCTGKAPVTDTETEPDEKPEKTKSGGSGTLILVLLVALAAGGAGYYFKIYKPKKDLD--DAE +T + PEP E N+ + ++T TEP++K + ++++ GGAGYYFKIY+PK++ + EENETAVVSTPEP-----------ESNSETDI---------SSETSSETSTEPEQKSDTQMLLLVLAVVVI------GGGAGYYFKIYRPKQEQAALAED DFDELTGGDEEETVNEDEDVDAQEETRQTGDEEPA +FDE +E ++ + E TG++E A EFDEYEADPYDEQEDDTPPWEVDGEESDTGEDEDA
Show aligned area	153952918	Clostridium kluyveri DSM 555	hypothetical protein CKL_0281	225	3e-18	0.37	0.52
ATKPAAGTGSAKPSASASAAPDEETDTTPRDPIPLTPDGQATVLDNATGEDGKEFYTIQTPDENVFYLIIDNQRDTENVYFLNAVTEADLMALAVKEDDT +T A G P + + A E T P P TP G TV++ AT EDGK+FYTI TPDENVFYL+ID QR+ +NVYFLNAVTE DL+ALA K +DT STMAYASGGEETPEVTEAPATSETTSA----PNPFTPAGTGTVVNTATDEDGKQFYTITTPDENVFYLVIDLQREQDNVYFLNAVTEKDLLALAEKSEDT P--QTDAIPDPEPACICTEQCAAGEVNTACPVCTLTRKDCTGKAPVTDTETEPDEKPEKTKSGGSGTLILVLLVALAAGGAGYYFKIYKPKKDLD--DAE +T + PEP E N+ + ++T TEP++K + ++++ GGAGYYFKIY+PK++ + EENETAVVSTPEP-----------ESNSETDI---------SSETSSETSTEPEQKSDTQMLLLVLAVVVI------GGGAGYYFKIYRPKQEQAALAED DFDELTGGDEEETVNEDEDVDAQEETRQTGDEEPA +FDE +E ++ + E TG++E A EFDEYEADPYDEQEDDTPPWEVDGEESDTGEDEDA
Show aligned area	150391673	Alkaliphilus metalliredigens QYMF	hypothetical protein Amet_3978	259	3e-06	0.27	0.41
NPATTTATKPAAGTGSAKPSASASAAPDEET-----DTTPRDPIPLTPDGQATVLDNATGEDGKEFYTIQTPDENVFYLIIDNQRDTENVYFLNAVTEAD N + ATK GS S + P + T D ++P+ L ++F + +T VF+LIID+ + +NV L V E D NAINSLATKQHTAQGSVIESTNVEGQPYDLTLLSDEDKAGKNPLEL-----------------RQFVSFETKSGKVFHLIIDHSQSVDNVKMLTEVGEQD LMALAVKEDDTP---QTDAIP-DPEPACICTEQCAAGEVNTACPVCTLTRKDCTGKAPVTDTETEPDEKPEKTKSGGSGTLILVLLVALAAGGAGYYFKI L+ L + + + D + D +P +E + EVN E E P K+ S LI++++ ++ AG AG+YFKI LLNLIEENAEVALILKQDVLENDKKPISTQSELNPSFEVN------------------------ELTEVPVGEKNNSS--LIIIIVASVLAGAAGWYFKI YKPKKDLDDAEDFDE YKPK+ E+ DE YKPKQSTTYDEEVDE
Show aligned area	119775587	Shewanella amazonensis SB2B	1,4-alpha-glucan branching enzyme	841	3e-05	0.41	0.55
KQKPSTGQTQPPATTAPVT----STTPAPTTPATSATTPPTTPTTNPATTTATKPAAGTGSAKPSASASAAPDE K KP T +T+P T PVT STT A S T P T P+T P+TT +TKP+A + + PS +A ++ KAKPGT-KTKPVTQTKPVTKAKASTTDNAPAKAKSGTKPSTKPSTKPSTTPSTKPSAKSVAKAPSNAAKTKAED
Show aligned area	126699468	Clostridium difficile 630	putative cell surface protein	523	8e-05	0.26	0.46
DGKEFYTIQTPDENVFYLIIDNQRDTENVYFLNAVTEADLMALAVKEDDTPQTDAIPDPEPACICTEQCAAGEVNTACPVCTLTRKDCTGKAPVTDTETE D ++F T T + F+LII++ D+E V L V+E DL+ + E P+ + + + +++ E DARQFVTFTTKNGKTFHLIINHDEDSEKVMLLTEVSEDDLLNMV--EKKAPEKEIVKE-------------------------------------ESQKE PDEKPEKTKSGGSGTLILVLLVALAAGGAGYYFKIYKPKKD--LDDAEDFDELTGGDEEETVNE ++ +K +S +GT ++++LV A GAGYYFK+ K K+D L+ E+ D+ + EE+ NE EPKQVKKEESSNTGTYLILILVVAGALGAGYYFKVIKKKEDKELEGFEEEDDDFFSEAEESENE
Show aligned area	126697991	Clostridium difficile 630	putative cell surface protein	513	3e-04	0.25	0.41
SATTPPTTPTTNPATTTATKPAAGTGSAKPSASASAAPDEETDTTPRDPIPLTPDGQATVLDNATGEDGKEFYTIQTPDENVFYLIIDNQRDTENVYFLN +A P + + + G A + A A+ E D ++ D + D ++F T QT + FYLII++ D+ENV L TAKAPANNSQDSSMGSASKSVNTNKGVASSPSKARASVTENKDNANKEYPIHHGDSSDNKETDQYSADARQFITFQTKNGKTFYLIINHDEDSENVMLLT AVTEADLMALAVKEDDTPQTDAIPDPEPACICTEQCAAGEVNTACPVCTLTRKDCTGKAPVTDTETEPDEKPEKTKSGGSGTLILVLLVALAAGGAGYYF V+E DL+ + V++ + P+ + + + PV + E +P++K EK+ G T I++LLV A GAGYYF EVSEDDLLNM-VEKKEAPKQEVVKE---------------------------------EPVKE-EVKPEKKDEKSNLG---TYIILLLVVGGALGAGYYF

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