LAB-Secretome DB


LAB-Secretome DB A comparative analysis of the predicted secretomes of Lactic Acid Bacteria

Protein with distant homolog in non-LAB species

GI:116333525
NCBI info	116333525	Gene:	-	Synonym:	LVIS_0884
SCL:	@N-terminally anchored (with CS)	Length	226	COG	-
Species:	Lactobacillus_brevis_ATCC_367	Location	912304..912984	Strand:	-
Product:	N-acetylmuramoyl-L-alanine amidase
Sequence:	MKRWWKATWCIIIVLTVVVVTGQALTATAATKAVKPRVNRTVKAPTKHQYILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFYNPK QDIVKDTLTYHKGSYKLNRHATVVMFHLDAAGGHGGHVIIHKRRPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRT DMAHIRKNIGKIAKADIEAITYGNIR

Protein Domain structure of 116333525 (Scale up the web page to see more details)

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Distant Homologs of 116333525 in the non-LAB species

Alignment	GI	Species	Product	Length	Eval	Identities	Positives
Show aligned area	70726749	Staphylococcus haemolyticus JCSC1435	amidase (peptidoglycan hydrolase)	464	1e-18	0.37	0.53
ILVMGHGAG----DSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFYNPK---QDIVKDTLTYHK-------GSYKLNRHA---TVVMFHLDAAG- +LV GHG G D GA NG E F R++++P+++KY K H+ V Y K QD+ +DTL + G Y + ++ +V FHLDAA LLVAGHGKGAYSNDPGAVANGYNERDFNRKNIIPKVKKYLEKSGHN-VVLYGGKSMNQDLYQDTLYGQRVGNYSDYGLYWVKKNVKPDVIVEFHLDAASP -GHGGHVIIHKRRPTAR-DKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKNIGKIAKADIEAI GGHVII+ + P DK ++ + K VG R G + R DL N NV K ++Y L+E GFIT++ DM +I ++ K EAI QASGGHVIINNQYPADNIDKAISSALDKTVGKIR---GVTARNDLLNANVAGKLNLNYRLVELGFITSKKDMNYINDHLDSFTKRIAEAI
Show aligned area	148267347	Staphylococcus aureus subsp. aureus JH9	CHAP domain-containing protein	470	3e-18	0.35	0.50
TATAATKAVKPRVNRTVKAPTKHQYILVMGHGAG----DSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTF--YNPKQDIVKDTLTYHK-GSYKLN TA AVKP + K + +LV GHG G D GA NG E F R++++P+++KY V ++ + + + QD+ +DTL + G+YK TANKLRSAVKPV--KQDKLSKGKKIMLVAGHGIGAYSNDPGAVANGENERDFNRKNIIPRVKKYLESVGNTVLLYGGNSMNQDLYQDTLYGQRVGNYKDY ---------RHATVVMFHLDAAG--GHGGHVIIHKRRPTAR-DKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIR + ++ FHLD+A GGHVII R P DK L+ + K VG R G + R DL N NV ++Y LIE GFIT+ D+ +I+ GMYWIKSEVKPDAIIEFHLDSASPQASGGHVIISDRFPADDIDKALSSALDKTVGKIR---GVTPRGDLLNANVSADLNLNYRLIELGFITSTKDLNYIK KNIGKIAKADIEAI N+ K EAI NNLDSFTKRIAEAI
Show aligned area	150393399	Staphylococcus aureus subsp. aureus JH1	CHAP domain-containing protein	470	3e-18	0.35	0.50
TATAATKAVKPRVNRTVKAPTKHQYILVMGHGAG----DSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTF--YNPKQDIVKDTLTYHK-GSYKLN TA AVKP + K + +LV GHG G D GA NG E F R++++P+++KY V ++ + + + QD+ +DTL + G+YK TANKLRSAVKPV--KQDKLSKGKKIMLVAGHGIGAYSNDPGAVANGENERDFNRKNIIPRVKKYLESVGNTVLLYGGNSMNQDLYQDTLYGQRVGNYKDY ---------RHATVVMFHLDAAG--GHGGHVIIHKRRPTAR-DKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIR + ++ FHLD+A GGHVII R P DK L+ + K VG R G + R DL N NV ++Y LIE GFIT+ D+ +I+ GMYWIKSEVKPDAIIEFHLDSASPQASGGHVIISDRFPADDIDKALSSALDKTVGKIR---GVTPRGDLLNANVSADLNLNYRLIELGFITSTKDLNYIK KNIGKIAKADIEAI N+ K EAI NNLDSFTKRIAEAI
Show aligned area	88195229	Staphylococcus aureus subsp. aureus NCTC 8325	petidoglycan hydrolase, putative	484	3e-18	0.36	0.48
ATAATKAV-KPRVNRTVKAPTKHQYILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL-------TYHKGSY ATA +AV KP+ + +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT G Y ATAKKQAVIKPK-----------KIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNNKDYGLY KLNRHA--TVVMFHLDAAG--GHGGHVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN-- + H V+ HLDAAG GGHVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN WVKSHGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYD ------IGKIAKADIEAITYGNIR G I I + GN++ LYSKLIAGAIHGKPIGGLVAGNVK
Show aligned area	49483674	Staphylococcus aureus subsp. aureus MRSA252	amidase	484	8e-18	0.37	0.49
ILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL----TYHKGSYKL-----NRHATVVMFHLDAAG--GHGG +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT +K Y L + V+ HLDAAG GG MLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGG HVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN--------IGKIAKADIEAITYGNIR HVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN G I I + GN++ HVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVK
Show aligned area	57652578	Staphylococcus aureus subsp. aureus COL	prophage L54a, amidase, putative	484	9e-18	0.37	0.49
ILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL----TYHKGSYKL-----NRHATVVMFHLDAAG--GHGG +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT +K Y L + V+ HLDAAG GG MLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGG HVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN--------IGKIAKADIEAITYGNIR HVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN G I I + GN++ HVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVK
Show aligned area	151221981	Staphylococcus aureus subsp. aureus str. Newman	phage amidase	484	9e-18	0.37	0.49
ILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL----TYHKGSYKL-----NRHATVVMFHLDAAG--GHGG +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT +K Y L + V+ HLDAAG GG MLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGG HVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN--------IGKIAKADIEAITYGNIR HVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN G I I + GN++ HVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVK
Show aligned area	151220525	Staphylococcus aureus subsp. aureus str. Newman	amidase	484	9e-18	0.37	0.49
ILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL----TYHKGSYKL-----NRHATVVMFHLDAAG--GHGG +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT +K Y L + V+ HLDAAG GG MLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGG HVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN--------IGKIAKADIEAITYGNIR HVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN G I I + GN++ HVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVK
Show aligned area	161509661	Staphylococcus aureus subsp. aureus USA300_TCH1516	bacteriophage amidase	484	9e-18	0.40	0.52
ILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL----TYHKGSYKL-----NRHATVVMFHLDAAG--GHGG +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT +K Y L + V+ HLDAAG GG MLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGG HVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN HVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN HVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKN
Show aligned area	87160059	Staphylococcus aureus subsp. aureus USA300	phiSLT ORF484-like protein, lysin	484	9e-18	0.40	0.52
ILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL----TYHKGSYKL-----NRHATVVMFHLDAAG--GHGG +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT +K Y L + V+ HLDAAG GG MLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGG HVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN HVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN HVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKN
Show aligned area	21283109	Staphylococcus aureus subsp. aureus MW2	truncated amidase	484	1e-17	0.36	0.48
ATAATKAV-KPRVNRTVKAPTKHQYILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL-------TYHKGSY ATA +AV KP+ + +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT G Y ATAKKQAVIKPK-----------KIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNNKDYGLY --KLNRHATVVMFHLDAAG--GHGGHVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN-- K + V+ HLDAAG GGHVII + DK + VIK +G R G + R DL N NV + I+Y L E GFITN+ DM I+KN WVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEININYRLSELGFITNKKDMDWIKKNYD ------IGKIAKADIEAITYGNIR G I I + GN++ LYSKLIAGAIHGKPIGGLVAGNVK
Show aligned area	49485860	Staphylococcus aureus subsp. aureus MSSA476	amidase	484	2e-17	0.36	0.48
ATAATKAV-KPRVNRTVKAPTKHQYILVMGHGAGDSGARGNGTTEATFLRQHLLPQLRKYAIKVKHSQVTFY---NPKQDIVKDTL-------TYHKGSY ATA +AV KP+ + +LV GHG D GA GNGT E F+R+++ P + KY H +V Y + QD+ +DT G Y ATAKKQAVIKPK-----------KIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGH-EVALYGGSSQSQDMYQDTAYGVNVGNNKDYGLY --KLNRHATVVMFHLDAAG--GHGGHVIIHKR-RPTARDKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRKN-- K + V+ HLDAAG GGHVII + DK + VIK +G R G + R DL N NV + ++Y L E GFITN+ DM I+KN WVKSQGYDIVLEIHLDAAGENASGGHVIISSQFNADTIDKSIQDVIKNNLGQIR---GVTPRNDLLNVNVSAEINMNYRLSELGFITNKKDMDWIKKNYD ------IGKIAKADIEAITYGNIR G I I + GN++ LYSKLIAGAIHGKPIGGLVAGNVK
Show aligned area	57867532	Staphylococcus epidermidis RP62A	prophage, amidase, putative	463	3e-15	0.34	0.47
AATKAVKPRVNRTVKAPTKHQYILVMGHGAG----DSGARGN--GTTEATFLRQHLLPQLRKYAIKVKHSQVTFYNP---KQDIVKDTL-------TYHK ++ A+ + +P + +LV GHG G D G E F+RQ ++P + KY +K V Y QD+ +DT T SSNNAIVRAAKNVLPSPKPMKVLLVAGHGKGAYSNDPGVVNTELDICERDFVRQKIVPNVAKY-LKQAEVNVQLYGGSTMNQDMYQDTRYGVNLGDTKRY GSYKLNRHA--TVVMFHLDAAG--GHGGHVIIHKRRPTAR-DKRLAQVIKKYVGLNRAYHGYSYRTDLKNCNVLRKRGIDYSLIETGFITNRTDMAHIRK G Y R +V FHLDAA GGHVII + D+RL +VI KYVG R G R +L N NV +Y L+E GFITN+TD+ +I + GMYWAARQGFDQIVEFHLDAASPQASGGHVIIDNNVYQDKIDERLHKVIDKYVGTIR---GIDKRDNLLNANVSADLNQNYRLVELGFITNKTDVRNIER NIGKIAKADIEAITYGNI ++ K EAI GN+ HLEAFTKEMAEAIV-GNV