LAB-Secretome DB


LAB-Secretome DB A comparative analysis of the predicted secretomes of Lactic Acid Bacteria

Protein with distant homolog in non-LAB species

GI:116332903
NCBI info	116332903	Gene:	-	Synonym:	LVIS_0233
SCL:	@Secretory(released) (with CS)	Length	613	COG	-
Species:	Lactobacillus_brevis_ATCC_367	Location	247737..249578	Strand:	+
Product:	Predicted protease
Sequence:	MKKMGLIVTSLVVGLICFGGIQGQAAKLVTVATPYRQSRLQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQS SATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFS DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATG GSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRS GRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGL GTVNFEKLARSYQ

Protein Domain structure of 116332903 (Scale up the web page to see more details)

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Distant Homologs of 116332903 in the non-LAB species

Alignment	GI	Species	Product	Length	Eval	Identities	Positives
Show aligned area	15893913	Clostridium acetobutylicum ATCC 824	periplasmic aspartyl protease	625	2e-91	0.35	0.54
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKI V++DIV+K + L Q T S +++ YL+ +F+ F S + LT Y +A +++ + L++ G INKAF V LK A Y GK VTIDIVIKLQNKSELQQYINDTVTPKSSNYRRYLSVAEFKKSFAPKSKQINELTEYLKAFGIKSEVYQDNLIVTATGTADQINKAFNVELKHASYKGKNF QFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVP SK+ P+LPK++A I ++G+++ + T K P + K + +P+ +K Y+ L +G G +++GI++ FW+Q G+ HASKKQPKLPKKIADNILCILGLSSYSSYTTKTVKVPNEFKPSNSNGPLSLNPSDLIKHYNVQPLYKNGASGKNESIGIVTLAEFNPNDAYSFWKQEGIK TTGR-LETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMN T R ++ G + G+D DET LD EQ+G +AP+A+V VY A +D G++DAF EN+ +S SWG SE+++ L T Y + N TDKRRIKVINVDGGS----GNDGADETTLDVEQSGALAPKAEVNVYVAPNTDPGFVDAFANVINENKCHQISASWGESEDLISYLVSQGQETKGYAEAFN TLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIE--ADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILL L Q A QGIS F A+GD+GAY S+ + P E D PADSP++TA GG+TL + T SV V +ER WG D + + L L QLFMQAAAQGISMFAAAGDSGAYD---SKENTPPSYELSVDNPADSPYITAAGGTTLAWQGTVKE-TSVKVDKERAWGWDYLYPAFDADGLYSSGK---L EELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGP-----------KLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVA ++ GGG S+++ TP YQ+G++GVN + K TA P+ GP +++ G +GRN PD+ +ADP TGY++Y N +GGTS VA DKYFVGGGGGFSKIFDTPDYQKGISGVNRFTGVKQWTASNPQ-GPLLLNVTRDAAQQIVTGKDTGRNVPDISMDADPYTGYNVY-MNGEMSSIGGTSIVA PQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRL-DAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSY PQ A + A++N + + ++G WNPQ+Y AQ+ +SP L D ++N N++Y G +YNQA GLG + KL S+ PQLAGLCALINDNNNTQVGFWNPQIYKFAQSSNSPLNPLNDTGSSNDNIFYTATKGTIYNQATGLGIPDIAKLNASF
Show aligned area	217979554	Methylocella silvestris BL2	Peptidase S53 propeptide	626	3e-51	0.31	0.46
VKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLK +K +A +S+ + L+PR +L A+ T D F +LTPQQF AKFG S+A +++ + L+ A +R G A I AF V+L MKSLASSSEISVTVALRPRDPNGAEELLSALTTPDDPQFHKFLTPQQFAAKFGPSAADVAKVIATLKGYGLRVEQATP-FTLRATGTPAKIESAFHVSLH T--ARYHGKKIQFSKQAPRLP----KQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPT---------------KFLKQYHASNLATSGQQGAG G +S AP P VA I +VG+ + K+PA++ + ++ + F + Y L +G G G QFDVPAQGGAAAYSYHAPATPPTAPDAVAGLISGIVGLDTKPHFRPHVQKAPAELSAVEGQQQQSGNPSLINPLGSLTVADFAQYYDVKPLYAAGVAGNG QTVGIISFGHVPTAAIKHFWRQAGVP-TTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLS +T+GII+ + + H+W + G+ + R+ G + DET LD EQ+G +AP A++ VY A ++ + DAF A +N A ++S+S RTLGIITLANFTPSDAFHYWTRVGLAVASNRMTLVNIDGGPGAPSDVSGSDETTLDVEQSGGLAPGARMIVYLAPNTNQAFFDAFAKAVNDNTADTVSVS WGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG---ISVNVTR WG E + + + +++LL Q A+QG S F A+GD GAY + + G+ D+PA P +TA GG+TL K+ F + +NV + WGAWEGFDQSTG--------FTNSLHSLLVQAAVQGQSFFAAAGDDGAYDVDRAIGVQAGGVTVDYPASDPAITAAGGTTLAGKQAFTVNGRPLVINVAK ERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAV-GPKSGPK--LIHGYR-----SGRNYPDVVANAD ER WG D + L PI + GGG+S ++G P YQ T RK + G K+ K + G R GRN PD+ ANAD ERVWGWDYLDPVCKKRKLD----PIDCGIFSVGGGGGVSIVFGIPDYQ-------TVTKRKGAVPIPGIKTSAKGETVQGARLPAGFQGRNVPDISANAD PITGY--DIYSKNSGWE---LMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYAL--AQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNF P TGY D S G+ GGTS VAPQF + A++ + R+GL N LY+L A + + N +Y G G Y+ AAG G ++ PNTGYSMDYTSNIHGFRTTTFNGGTSFVAPQFNGVTALLCQKANSRLGLINNPLYSLVRANAGKKAGGPIRSIATGDNWFYKGAQG--YSPAAGAGVLDV EKLA KLA TKLA
Show aligned area	34498974	Chromobacterium violaceum ATCC 12472	periplasmic aspartyl protease	635	1e-50	0.28	0.45
LQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKA +Q L V++ A + +++ I L R ++ V+T S ++ +LTP +FRA++ + A+ +++ +A L + LL +V G AT+ KA VQDLGKVEQAAPAQKLTVTIALSLRDRDAAARYLQEVHTPSSPNYHKFLTPSEFRARYAPTEASLAKVAARLQAAGLSVKRIGSTLL-QVSGPAATVQKA FAVNLKTARYHGKKIQFSKQAPRLPKQVAQP------IRAVVGVTNLMIAKSLTTKSPAQVK-------------HLTAKRSPTKFLKQYHASNLATSGQ F + + + +Q + P + + P ++AV+G+ + + + P+ ++ + K + T + Y+ + L G FGAEVHVFQ-NKSVVQGAAARYTAPVRASTPGIDLSDVQAVIGLDSRPHFRPHLRQLPSHLQASMDKSASAVTNGNAPGKWTVTDLARHYNITPLYNKGI QGAGQTVGIISFGHVPTAAIKHFWRQAGVPTT-GRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASS G G T+GI++ + +W G+ T RL G + D ET LD EQ+G IAP AK+ VY A + G++DAF A N A + HGQGATIGIVTLASFTPSDAFQYWSSIGLATDPNRLTVVDIDGGPGAPSDDGGSSETTLDVEQSGGIAPDAKIIVYQAPNTTQGFVDAFAKAIESNAADT LSLSWGLSENILRDLNRDHLLTPLYGDIMNT------LLAQGAIQGISTFVASGDTGAYGQNLSESSAMPG----IEADFPADSPWVTATGGSTLPIKKT LS+SWG E + + + P+ G N L Q A+QG + F ASGD+GAY +++ ++ +P + D PA+ ++TA G +T+P T LSVSWGEWEWFDQ---QSQAVNPVNGKSANVLQTYHDLFLQAALQGQTMFAASGDSGAY--DVNRAAPLPQYNKVLSVDSPANQQFITAAGATTVPTTLT FAPG---ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYL--TAVGPKSGPKLIHGYRSGRNY F P + + + ER WG D + G + K P+ GGG+S G P YQ + G+ A + L ++ P + GRN FHPNGKEMKIKIPTERAWGWD-YLNGLCK---ALGKDPVACGTFPVGDGGGVSSFIGRPFYQNWLPGMQNSPAGQQLVDSSQNPPQVIATLPANFKGRNV PDVVANADPITGYDIY--SKNSGWELM---GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDH---------SPFTRLDAATNNGNLYYVGQP PD+ N DP TGY +Y S +G+ + GGTS VAPQ A + A++N R+GL N LY L T H +P + A N G + G PDISMNGDPETGYVVYYTSSKTGFSIQTNNGGTSFVAPQLAGITALLNQSLGGRLGLLNFSLYGLVATGHGYQGFGRHGAPLRDITAGNNWGYNAHRG-- GKVYNQAAGLGT---VNFEKLARSY Y+QA G+G N + R Y ---YDQATGVGAPDVANLDAALRRY
Show aligned area	134292248	Burkholderia vietnamiensis G4	kumamolisin	528	5e-26	0.28	0.41
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G + AF+V L+ + + P LP ++ + AV+G+ + A+ P A+ + F AS GAG VVVLSGTIQQFEAAFSVKLERFEHRAIGQYRGRTGPIALPDELGDAVTAVLGLDSRPQARPHFRLRPP---FKPARGAAVTFTPVQLASLYGFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + I+ G AA I ++R G+ L G G+ S D E ALD E AG IAP AK+ VY A SD G++ A A + NR S QCIAIVELGGGYRAADIAQYFRGLGIDKPPTLVDVNVGTGRNAPTGEASGPDGEVALDIEIAGAIAPAAKIAVYFAPNSDAGFIQAVNAAVTDKTNRPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + ISISWGGPEAIWQAQS---------AHAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + A GGG+S ++ P +QQG+ R L + R PDV +A P TGY++ SEVAWNDE--------------------SAGGGAGGGGVSTMFDVPTWQQGLNVARVDGGRAPL----------------AKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + +MGGTSAVAP +AA+ A +N+ G NP LY L T N Y PG ++ GLG+ + KLA AVAGTP-AVMGGTSAVAPLWAALIARINAASGTSAGWINPVLYKHPDA-------LRDITKGSNGTYAAAPG--WDACTGLGSPDGAKLA
Show aligned area	50120389	Pectobacterium atrosepticum SCRI1043	putative protease	539	7e-26	0.30	0.43
GHVATINKAFAVNLKTARYHGKKIQFSKQAP--RLPKQVAQPIRAVVGVTNLMIAKS-LTTKSP-AQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQT G I +AF V+L ARY K F ++ LP+ + + AV+G+ + L P + + + +P + + YH GAGQ GTAGQIEQAFRVSL--ARYDHKNGAFRGRSGGIYLPEYLQGVVVAVLGLDERLATDCCLRMNRPFSNAEMRPSGYTPLELAEHYHFPE-----HDGAGQC VGIISFG---HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDET-------ALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AE +GII G +P ++H++++ GV ++ GGA DSD E +D E AGT+AP AK+ VY A +D G+L+A A + IGIIELGGGYRLPQ--LEHYFKRMGV-NPPQIVDVCVGGARNAPASLDSDKEVNPIDIEVQMDIEIAGTLAPAAKIVVYFAPNTDAGFLEAINAAIHDEK NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGI N S +S+SWG SE+ T + N A GI+ VASGD GA + + G+ +FPA SP+V A GG+ L +KT NAPSVISISWGSSES---------KWTAQSLRVYNQAFQTAAALGITVCVASGDQGA------KDGELHGLHVNFPASSPYVLACGGTRL--QKTM---- SVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPI E TW H +A+GGG+S+ + P +Q G++ + Y H R PDV NADP -----EETTW---------HSRD-------------GSATGGGVSQYFALPGWQLGLSLADKYGG----------------HHPLQHRGVPDVSGNADPE TGYDIYSKNSGWELMGGTSAVAPQFAAMAAVM TGY I N ++GGTSAVAP +A + A M TGYLI-EVNGREGVVGGTSAVAPLWAGLLARM
Show aligned area	117928668	Acidothermus cellulolyticus 11B	cell wall binding repeat 2-containing protein	1073	1e-25	0.26	0.41
AAKLVTV-ATPYRQSRLQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANN A +VTV A P + Q L + + +++VL+ R + L + V S ++ +LTP QF+ +FG ++ + +T FR LQ T+A AQPVVTVGAAPTPPADAQFLGPISGAQTGTVIQVNVVLRSRDSLGLDRFMAEVTNPHSPEYRHFLTPGQFQRRFGPTTQAINDVTAAFRNLGLQRTSA-L GLLIRVKGHVATINKAFAVNLKTARYHGKKI-QFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK--SPAQVKHLTAKRS------------------ G ++ G +A + A + R H +I + + AP+LP VA+ I +VG+ +L A + +P +V +A + GSVLGFSGSLAQFSSALHIGFARYRLHSGRIARINTAAPQLPVSVARYISGIVGLDDLARAAPAIPRHAAPTRVPVWSAGTAATPGSSTSCLSTSPTNAY --PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFS P + + Y L T G GAG TV + F ++ I F + G+ T ++ T G + E ALD E +AP A ++VY + YLPDQLARYYGLDTLFTVGALGAGVTVALPEFEPFLSSDIAAFNQCFGLTATPQVVTVDGGAGSGP-----GSGEAALDIETVAALAPSATIKVYEGP-N DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMP-----GIEADFPADSPW G L + + + +S+SW L E L YG + + Q +G + ASGD G+ G + + P + + PA P GAGILSVYNAIANDATVNIVSVSWLLCEAD---------LPSGYGASLRAIFQQMVAEGQTPLAASGDWGSAGCYPDITPSYPNGGNTALSVETPASFPE VTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLI VT GG++LP ++ T E W G P +GGGIS L+ P +Q +A A+ T G +G VTGVGGTSLP---------DLSGTSEVAWAGACTDGSGGSSP--------------CGTGGGISALWTMPTWQVPLA----ITAQSSGTPCGAPAGTYC- HGYRSGRNYPDVVANADPITGYDIY---------SKNSGWELMGGTSAVAPQFAAMAAVMNSD-RSQRMGLWNPQLYALAQTDHSPFTRLDAATNN R PDV A+ADP GY IY + N G+ ++GGTSA AP +AA+ A ++S R Q+ G N LY L + F + + N+ ------REVPDVSASADPSHGYVIYWTYVDPVTSTSNPGFYVIGGTSAAAPLWAALLADISSSCRPQQWGSINSTLYGLVGAGITLFRDITSGNND
Show aligned area	189352623	Burkholderia multivorans ATCC 17616	pseudomonalisin	579	3e-25	0.25	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T + + LK R L QLA VN S ++ YLTP++F A + + A + Y R + + A N LL+ +G T+ AF +L ELAAGETTDVVVSLKLRNADQLKQLARDVNRPGSARYRQYLTPERFLADYAPTEAQVKSVVDYLRKSGFVNIEVAPNRLLVSARGTAGTVKTAFNTSLVR ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF +Y G+ + ++P+ + + +V+G+ N+ A L + ++ + L A + + K++ AT AG TVGII+ G V +K F FQYAGRSGFANASTAQVPRALGDVVGSVLGLQNVARAHPMLRIGNVSKPQTLAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVSQTLQDLKRF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPR----AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNR G T KT G T DD D + D + + K+ Y A + + G AF A ++N A +++S G E D N ASSNGYATVATQTVKTNGTGTSGSYADDPDGQGEWDLDSQSIVGAAGGQVGKLVFYMADLNAPGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANA DHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQH D L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G DGTL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGANYTVSWPASSPHVLAIGGTTLYTTSAGA------FSSETVWNEGLDSNGK--- PLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVA A+GGG+S L P +Q G S R PDV +A TG IY+ + + GTS A --------------LWATGGGVSTLLPAPAWQSG-----------------------------SNRRLPDVSFDAAQSTGAYIYNYGQ-LQQIRGTSLAA PQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ P F A + + +G LY + S R D + NNG Y G ++ G G++N L + Q PIFTGFWARLLAANGTGLGFPAANLYRAIPANPS-LVRYDVVSGNNGYQGYGYTAGTGWDYPTGFGSLNIANLNKLIQ
Show aligned area	161521202	Burkholderia multivorans ATCC 17616	peptidase S53 propeptide	579	3e-25	0.25	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T + + LK R L QLA VN S ++ YLTP++F A + + A + Y R + + A N LL+ +G T+ AF +L ELAAGETTDVVVSLKLRNADQLKQLARDVNRPGSARYRQYLTPERFLADYAPTEAQVKSVVDYLRKSGFVNIEVAPNRLLVSARGTAGTVKTAFNTSLVR ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF +Y G+ + ++P+ + + +V+G+ N+ A L + ++ + L A + + K++ AT AG TVGII+ G V +K F FQYAGRSGFANASTAQVPRALGDVVGSVLGLQNVARAHPMLRIGNVSKPQTLAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVSQTLQDLKRF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPR----AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNR G T KT G T DD D + D + + K+ Y A + + G AF A ++N A +++S G E D N ASSNGYATVATQTVKTNGTGTSGSYADDPDGQGEWDLDSQSIVGAAGGQVGKLVFYMADLNAPGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANA DHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQH D L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G DGTL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGANYTVSWPASSPHVLAIGGTTLYTTSAGA------FSSETVWNEGLDSNGK--- PLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVA A+GGG+S L P +Q G S R PDV +A TG IY+ + + GTS A --------------LWATGGGVSTLLPAPAWQSG-----------------------------SNRRLPDVSFDAAQSTGAYIYNYGQ-LQQIRGTSLAA PQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ P F A + + +G LY + S R D + NNG Y G ++ G G++N L + Q PIFTGFWARLLAANGTGLGFPAANLYRAIPANPS-LVRYDVVSGNNGYQGYGYTAGTGWDYPTGFGSLNIANLNKLIQ
Show aligned area	146304135	Metallosphaera sedula DSM 5348	peptidase S8 and S53, subtilisin, kexin, sedolisin	1271	5e-25	0.32	0.46
DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLL---TPLYGDIMNTLLAQGAIQGISTFVASGDT D ETALD E +AP A V A S +A +++ A +S+SWGL EN++ TP Y ++ A G +GIS F +SGD DVETALDVEAVHAMAPYAHVIAVVASNSGSALFEAVDLVVSQDLAQVVSMSWGLPENLIGASGFYAYFQGSTPNY-PYLDYYFALGTAEGISFFASSGDN GAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQ GAYG L+ + +FPA SP+VTA GG++L + T G N T+G F + P Q+ + + + +SGGG+S L+ P YQ GAYGGTLTSYGGV-----NFPASSPFVTAVGGTSLYVNST--SGSLENKDANVTYG---FETAWGVLP-QYFEPGV----TSVSSGGGMSTLFPAPWYQN GVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDH +YL A S R PDV A+A+P TG IY++ E++GGTS +P +A + A ++S ++ +GL NP LY + -----------QYLNA--------------SYREVPDVSADANPYTGLVIYAEGVE-EVIGGTSLASPLWAGVTADLDSQLNESLGLLNPILYWIYSNST SPF--TRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ S T N Y G YN GLGT N+ L ++ + STLYSQAFHQVTVGFNGIYTATSG--YNMVTGLGTPNYPGLLKAVK
Show aligned area	53716275	Burkholderia mallei ATCC 23344	serine protease, kumamolysin	524	7e-25	0.27	0.42
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ +Y G+ + LP ++ + AV+G+ + A+ P L A+ + A+ LVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDIT-----LPDELHGIVTAVLGLDDRPQARPHFRLRPT---FLPARAPAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L + G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQQYFGGLGLARQPKLVDVSVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T +++L A G++ ASGD G+ L + + DFPA SP+V A GG+ L PG TNRPSVVSISWGAAEAN---------WTSQSIQAFDSVLQSAAALGVTVCAASGDDGS-NDGLQDGTN----HVDFPASSPYVLACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV + P QGIR--SEVVWNDE-------------------------AAGGGVSAVFDVPQWQSGLSAT---------LAQGGGASP------LAKRGVPDVAGDVSP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY+++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + +NG Y PG ++ GLG+ + K+ ATGYEVFVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHDI-----SVGDNGA--YAATPG--WDACTGLGSPDGAKV
Show aligned area	189353828	Burkholderia multivorans ATCC 17616	kumamolisin	529	1e-24	0.27	0.41
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG-LLIRVKGHVATINKAFAVNLKTARYHGKK + + I+L+ ++ L L + + D Q+ L+ F +F S + + R L + ++ + G + AF V L+ +H IHVTIMLRRQEEGQLDTLLQRLASGDPQAKP--LSRDAFAQRFSASPDDIRKTEDFARRHQLTVDRVDPAESVVVLSGTIKQFETAFGVTLERFEHHAIG IQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-IKHFWRQAGVPT + P LP ++ + AV+G+ + A+ P K S T F AS GAGQ + I+ G AA I ++ G+ T QYRGRSGPIALPDELGDAVTAVLGLDSRPQARPHFRLRPP-FKPARGAASVT-FTPPQLASLYGFPAGDGAGQCIAIVELGGGYRAADIARYFSGLGIKT TGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDI RL G GD + D E ALD E AG IAP A + VY A SD G++ A A +N+ S +S+SWG E I + + PPRLVDVNVGTGRNTPTGDPNGPDGEVALDIEIAGAIAPAATIAVYFAPNSDAGFIQAVNAAVNDTKNKPSVISISWGGPEAIWQAQS---------AQA MNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILL N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + E W + FNRVLQAAAAQGITVCAASGDSGS-GDGLQDGTD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR--SEVAWNDE-------------------- EELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMN A GGG+S L+ P +Q G++ +R L + R PDV +A P TGY++ + +MGGTSAVAP +AA+ A +N ASGGGAGGGGVSTLFDLPAWQHGLSLTRADGSRAPL----------------AKRGVPDVAGDASPQTGYEVSVAGTP-AVMGGTSAVAPLWAALIARIN SDRSQRMGLWNPQLY + G NP LY AAAGTSAGWINPTLY
Show aligned area	161519990	Burkholderia multivorans ATCC 17616	peptidase S53 propeptide	529	1e-24	0.27	0.41
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG-LLIRVKGHVATINKAFAVNLKTARYHGKK + + I+L+ ++ L L + + D Q+ L+ F +F S + + R L + ++ + G + AF V L+ +H IHVTIMLRRQEEGQLDTLLQRLASGDPQAKP--LSRDAFAQRFSASPDDIRKTEDFARRHQLTVDRVDPAESVVVLSGTIKQFETAFGVTLERFEHHAIG IQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-IKHFWRQAGVPT + P LP ++ + AV+G+ + A+ P K S T F AS GAGQ + I+ G AA I ++ G+ T QYRGRSGPIALPDELGDAVTAVLGLDSRPQARPHFRLRPP-FKPARGAASVT-FTPPQLASLYGFPAGDGAGQCIAIVELGGGYRAADIARYFSGLGIKT TGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDI RL G GD + D E ALD E AG IAP A + VY A SD G++ A A +N+ S +S+SWG E I + + PPRLVDVNVGTGRNTPTGDPNGPDGEVALDIEIAGAIAPAATIAVYFAPNSDAGFIQAVNAAVNDTKNKPSVISISWGGPEAIWQAQS---------AQA MNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILL N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + E W + FNRVLQAAAAQGITVCAASGDSGS-GDGLQDGTD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR--SEVAWNDE-------------------- EELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMN A GGG+S L+ P +Q G++ +R L + R PDV +A P TGY++ + +MGGTSAVAP +AA+ A +N ASGGGAGGGGVSTLFDLPAWQHGLSLTRADGSRAPL----------------AKRGVPDVAGDASPQTGYEVSVAGTP-AVMGGTSAVAPLWAALIARIN SDRSQRMGLWNPQLY + G NP LY AAAGTSAGWINPTLY
Show aligned area	170737348	Burkholderia cenocepacia MC0-3	peptidase S53 propeptide	529	1e-24	0.29	0.41
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G +A AF+V L+ + + P LP + + AV+G+ + A+ P A + F AS GAG VVVLSGTIAQFEAAFSVKLERFEHRSIGQYRGRSGPIALPDDLGDAVTAVLGLDSRPQARPHFRFRPPFKPARGA--AAVTFTPIQLASLYDFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + II G AA I+ ++R G+ T +L G G+ + D E ALD E AG IAP AK+ VY A SD G++ A A + N+ S QCIAIIELGGGYRAADIQQYFRGLGITTPPKLVDVNVGTGRNAPTGEPNGPDGEVALDIEIAGAIAPAAKIAVYFAPNSDAGFIQAVNAAVTDKTNQPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + ISISWGGPEAIWQAQS---------AQAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E TW + A GGG+S L+ P +QQG+ + L + R PDV +A P TGY++ SEVTWNDE--------------------ASGGGAGGGGVSALFDLPAWQQGLKVARADGSTTPL----------------AKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + +MGGTSAVAP +AA+ A +N+ G NP LY H R +NG Y G ++ GLG+ N +LA SVAGTP-AVMGGTSAVAPLWAALIARINAANGASAGWINPVLY-----KHPGALRDITKGSNGT--YAAASG--WDACTGLGSPNGAQLA
Show aligned area	115359386	Burkholderia ambifaria AMMD	peptidase S8 and S53, subtilisin, kexin, sedolisin	529	1e-24	0.29	0.42
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G + AF+V L+ + + P LP ++ + AV+G+ + A+ P K S T F AS GAG VVVLSGTIQQFEAAFSVKLERFEHRSIGQYRGRSGPIALPDELGDVVTAVLGLDSRPQARPHFRLRPP-FKPARGATSVT-FTPPQLASLYGFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + I+ G A I+ ++R G+ + G NGD + D E ALD E AG IAP AK+ VY A SD G++ A A + NR S QCIAIVELGGGYRATDIQQYFRGLGIDKPPTVVDVNVGTGRNTPNGDANGPDGEVALDIEIAGAIAPAAKIAVYFAPNSDAGFIQAVNAAVTDKTNRPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + ISISWGGPEAIWQAQS---------AHAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E TW D A GGG+S ++ P +Q+G+ A+ S L + R PDV +A P TGY++ SEITWNDD--------------------AAGGGAGGGGVSTMFDVPAWQKGLT-----------VALADGSSRPL-----AKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA S +MGGTSAVAP +AA+ A +N+ G NP LY H R +NG Y G ++ GLG+ + KLA -SIAGTPAVMGGTSAVAPLWAALIARINAAAGASAGWINPVLY-----KHPGALRDITKGSNGT--YAAASG--WDACTGLGSPDGAKLA
Show aligned area	170735986	Burkholderia cenocepacia MC0-3	peptidase S53 propeptide	577	2e-24	0.26	0.39
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYF-RACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T ++ + LK R L QLA VN S ++ YLT +QF A + + A + Y ++ A N LLI G T+ AF +L ELAAGETTNVVVSLKLRNAAQLKQLARDVNRPGSAHYRQYLTHEQFLANYAPTDAQVQSVVDYLHKSGFTNVEVAPNRLLISASGTAGTVKTAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF Y G+ + ++P+ + + +V+G+ ++ A+ L + A+ + L A + + K++ AT AG TVGII+ G V +K F FEYAGRSGFANTSTAQVPRALGDVVGSVLGLQSVARARPLLRIGNVAKPQALAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVSQTLQDLKQF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPR-AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH G T KT G + D E LD++ G+ + K+ Y A + + G AF A ++N A +++S G E D N D TSSNGYGTVSTQTVKTNGTGGSYTDDQDGQGEWDLDSQSIVGSAGGQVGKLVFYMADLNAAGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANADG LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G TL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVLAIGGTTLYTTSAGA------FSNETVWNEGLDSNGK----- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQ A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS AP ------------LWATGGGVSTILPAPSWQSG-----------------------------SNRQLPDVAFDAAQSTGAYIYNYGQ-LQQIGGTSLAAPI FAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKL F A + + +G YA + H R D + NNG Y + G ++ G G++N L FTGFWARLLAANGTGLGFPASNFYADIPS-HPSLVRYDVVSGNNGYQGYGYKAGTGWDLTTGFGSLNIANL
Show aligned area	116692021	Burkholderia cenocepacia HI2424	peptidase S8 and S53, subtilisin, kexin, sedolisin	577	2e-24	0.26	0.39
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYF-RACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T ++ + LK R L QLA VN S ++ YLT +QF A + + A + Y ++ A N LLI G T+ AF +L ELAAGETTNVVVSLKLRNAAQLKQLARDVNRPGSAHYRQYLTHEQFLANYAPTDAQVQSVVDYLHKSGFTNVEVAPNRLLISASGTAGTVKTAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF Y G+ + ++P+ + + +V+G+ ++ A+ L + A+ + L A + + K++ AT AG TVGII+ G V +K F FEYAGRSGFANTSTAQVPRALGDVVGSVLGLQSVARARPLLRIGNVAKPQALAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVSQTLQDLKQF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPR-AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH G T KT G + D E LD++ G+ + K+ Y A + + G AF A ++N A +++S G E D N D TSSNGYGTVSTQTVKTNGTGGSYTDDQDGQGEWDLDSQSIVGSAGGQVGKLVFYMADLNAAGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANADG LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G TL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVLAIGGTTLYTTSAGA------FSNETVWNEGLDSNGK----- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQ A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS AP ------------LWATGGGVSTILPAPSWQSG-----------------------------SNRQLPDVAFDAAQSTGAYIYNYGQ-LQQIGGTSLAAPI FAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKL F A + + +G YA + H R D + NNG Y + G ++ G G++N L FTGFWARLLAANGTGLGFPASNFYADIPS-HPSLVRYDVVSGNNGYQGYGYKAGTGWDLTTGFGSLNIANL
Show aligned area	107026787	Burkholderia cenocepacia AU 1054	peptidase S8 and S53, subtilisin, kexin, sedolisin	577	2e-24	0.26	0.39
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYF-RACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T ++ + LK R L QLA VN S ++ YLT +QF A + + A + Y ++ A N LLI G T+ AF +L ELAAGETTNVVVSLKLRNAAQLKQLARDVNRPGSAHYRQYLTHEQFLANYAPTDAQVQSVVDYLHKSGFTNVEVAPNRLLISASGTAGTVKTAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF Y G+ + ++P+ + + +V+G+ ++ A+ L + A+ + L A + + K++ AT AG TVGII+ G V +K F FEYAGRSGFANTSTAQVPRALGDVVGSVLGLQSVARARPLLRIGNVAKPQALAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVSQTLQDLKQF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPR-AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH G T KT G + D E LD++ G+ + K+ Y A + + G AF A ++N A +++S G E D N D TSSNGYGTVSTQTVKTNGTGGSYTDDQDGQGEWDLDSQSIVGSAGGQVGKLVFYMADLNAAGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANADG LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G TL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVLAIGGTTLYTTSAGA------FSNETVWNEGLDSNGK----- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQ A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS AP ------------LWATGGGVSTILPAPSWQSG-----------------------------SNRQLPDVAFDAAQSTGAYIYNYGQ-LQQIGGTSLAAPI FAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKL F A + + +G YA + H R D + NNG Y + G ++ G G++N L FTGFWARLLAANGTGLGFPASNFYADIPS-HPSLVRYDVVSGNNGYQGYGYKAGTGWDLTTGFGSLNIANL
Show aligned area	206564318	Burkholderia cenocepacia J2315	serine-carboxyl peptidase	529	3e-24	0.29	0.42
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G + AF+V L+ + + P LP ++ + AV+G+ + A+ P A + F AS GAG VVVLSGTIRQFETAFSVKLERFEHRSIGQYRGRSGPIALPDELGDAVTAVLGLDSRPQARPHFRFRPPFKPARGA--AAVTFTPIQLASLYDFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + II G AA I+ ++R G+ T +L G G+ + D E ALD E AG IAP AK+ VY A SD G++ A A + N+ S QCIAIIELGGGYRAADIQQYFRGLGITTPPKLVDVNVGTGRNAPTGEPNGPDGEVALDIEIAGAIAPAAKIAVYFAPNSDAGFIQAVNAAVTDKTNQPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + ISISWGGPEAIWQAQS---------AHAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E TW + A GGG+S L+ P +QQG+ K A G S P + R PDV +A P TGY++ SEVTWNDE--------------------ASGGGAGGGGVSALFDLPAWQQGL---------KVARADG-SSTP------LAKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + +MGGTSAVAP +AA+ A +N+ G NP LY L T N Y G ++ GLG+ N +LA SVAGTP-AVMGGTSAVAPLWAALIARINAAAGASAGWINPVLYKHPDA-------LRDITKGSNGTYAAASG--WDACTGLGSPNGAQLA
Show aligned area	134293094	Burkholderia vietnamiensis G4	sedolisin	579	3e-24	0.25	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T + + LK R L QLA VN + + YLT +QF A + + A + Y R + + A N LL+ G T+ AF +L ELAAGETADIVVSLKLRNAAQLKQLARDVNRPGNAHYGQYLTHEQFLADYAPTEAQVKSVVDYLRKSGFVNIEVAPNRLLVSAHGTAGTVKTAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF +Y G+ + ++P+ + + +V+G+ N+ A+ L + A+ + L A + + K++ AT AG TVGI++ G V +K F FQYAGRAGFANASTAQVPRALGDVVGSVLGLQNVARARPMLRIGNVAKPQALAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIVTIGGVSQTLQDLKQF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPR----AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNR G T KT G T DD D + D + + K+ Y A + + G AF ++N A +++S G E D N TSSNGYGTVATQAVKTNGTGTSGSYSDDQDGQGEWDLDSQSIVGSAGGQVGKLVFYMADLNAAGNTGLTQAFNRVVSDNTAKVINVSLGWCET---DANA DHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQH D L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G DGTL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGSNYTVSWPAASPHVLAIGGTTLYTTSAGA------FSNETVWNEGLDGNGK--- PLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVA A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS A --------------LWATGGGVSTILPAPAWQSG-----------------------------SNRRLPDVSFDAAQSTGAYIYNYGQ-LQQIGGTSLAA PQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ P F A + + +G + YA ++ S R D + NNG Y G ++ G G++N L + Q PIFTGFWARLLAANGTGLGFPAARFYARIPSNPS-LVRYDVVSGNNGYQGYGYTAGTGWDYPTGFGSLNVTNLNKLIQ
Show aligned area	206562812	Burkholderia cenocepacia J2315	putative pepstatin-insensitive carboxyl proteinase	577	6e-24	0.25	0.39
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYF-RACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T ++ + LK R L QLA VN S ++ YLT +QF A + + A + Y ++ A N LL+ G T+ AF +L ELAAGETTNVVVSLKLRNATQLKQLARDVNRPGSAHYRQYLTHEQFLANYAPTDAQVKSVVDYLHKSGFTNVEVAPNRLLVSASGTAGTVKAAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF Y G+ + ++P+ + + +V+G+ ++ A+ L + A+ + L A + + K++ AT AG TVGII+ G V +K F FEYAGRSGFANTSTAQVPRALGDVVGSVLGLQSVARARPMLRIGNVAKPQALAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVAQTLQDLKQF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPR-AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH G T KT G + D E LD++ G+ + K+ Y A + + G AF A ++N A +++S G E D N D TSSNGYGTVSTQTVKTNGTGGSYTDDQDGQGEWDLDSQSIVGSAGGQVGKLVFYMADLNAAGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANADG LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G TL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGANYTVSWPASSPHVLAIGGTTLYTTSAGA------FSNETVWNEGLDSNGK----- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQ A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS AP ------------LWATGGGVSTILPAPSWQSG-----------------------------SNRQLPDVSFDAAQSTGAYIYNYGQ-LQQIGGTSLAAPI FAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKL F A + + +G YA + H R D + NNG Y + G ++ G G++N L FTGFWARLLAANGTGLGFPAGNFYADIPS-HPSLVRYDVTSGNNGYQGYGYKAGTGWDLTTGFGSLNIANL
Show aligned area	78063010	Burkholderia sp. 383	sedolisin	577	7e-24	0.25	0.39
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYF-RACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T ++ + LK R L QL+ VN S ++ YLT QF A + + A + Y ++ + A N LL+ +G T+ AF +L ELAAGETTNVVVSLKLRNAAQLKQLSRDVNRPGSAQYRQYLTHAQFLANYAPTEAQVKSVVDYLHKSGFVNVEVAPNRLLVSARGTAGTVKTAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSL-----TTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-- Y G+ + ++P+ + + +V+G+ ++ A+ L +K A P +F Y+A+ + T+ AG TVGII+ G V FEYAGRAGFANTSTAQVPRALGGVVGSVLGLQSVAHARPLLHIGNVSKPQALAAGTATGHYPKEFPGLYNATGVPTA----AGVTVGIITIGGVSQTLQD IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPR-AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDL +K F G T +T G + D E LD++ G+ + K+ Y A + + G AF A ++N A +++S G E D LKQFTSSNGYSTVSTQTVQTNGSGGTYTDDQDGQGEWDLDSQSIVGSAGGKVGKLVFYMADLNASGNTGLTQAFNQAVSDNTAKVINVSLGWCET---DA NRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYH N D + D + A QG + V+SGD G Y N +PA SP V A GG+TL + A + E W + G NADGTI-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVVAIGGTTLYTTSSGA------FSNETVWNEGLDGNGK- QHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSA A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS ----------------LWATGGGVSTILPAPSWQSG-----------------------------SNRQLPDVSFDAAQSTGAYIYNYGQ-LQQIGGTSL VAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKL AP F + A + + +G + YA ++ S R D + NNG Y G ++ G G++N L AAPIFTGLWARLLAANGTGLGFPAGKFYADIPSNPS-LVRYDVVSGNNGYQGYGYNAGTGWDYTTGFGSLNIANL
Show aligned area	116693373	Burkholderia cenocepacia HI2424	peptidase S8 and S53, subtilisin, kexin, sedolisin	529	7e-24	0.29	0.41
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G +A AF+V L+ + + P LP + + AV+G+ + A+ P A + F AS GAG VVVLSGTIAQFEAAFSVKLERFEHRSIGQYRGRSGPIVLPDDIGDAVTAVLGLDSRPQARPHFRFRPPFKPARGA--AAVTFTPIQLASLYDFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + II G AA I+ ++R G+ T +L G G+ + D E ALD E AG IAP AK+ VY A SD G++ A A + N+ S QCIAIIELGGGYRAADIQQYFRGLGITTPPKLVDVNVGTGRNAPTGEPNGPDGEVALDIEIAGAIAPAAKIAVYFAPNSDAGFIQAVNAAVTDKTNQPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA S +V GG+ L PG + ISISWGGPEAIWQAQS---------AQAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSSYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E TW + A GGG+S L+ P +QQG+ + L + R PDV +A P TGY++ SEVTWNDE--------------------ASGGGAGGGGVSALFDLPAWQQGLKVARADGSTTPL----------------AKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + +MGGTSAVAP +AA+ A +N+ G NP LY H R +NG Y G ++ GLG+ N +LA SVAGTP-AVMGGTSAVAPLWAALIARINAANGASAGWINPVLY-----KHPGALRDITKGSNGT--YAAASG--WDACTGLGSPNGAQLA
Show aligned area	107025445	Burkholderia cenocepacia AU 1054	peptidase S8 and S53, subtilisin, kexin, sedolisin	529	7e-24	0.29	0.41
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G +A AF+V L+ + + P LP + + AV+G+ + A+ P A + F AS GAG VVVLSGTIAQFEAAFSVKLERFEHRSIGQYRGRSGPIVLPDDIGDAVTAVLGLDSRPQARPHFRFRPPFKPARGA--AAVTFTPIQLASLYDFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + II G AA I+ ++R G+ T +L G G+ + D E ALD E AG IAP AK+ VY A SD G++ A A + N+ S QCIAIIELGGGYRAADIQQYFRGLGITTPPKLVDVNVGTGRNAPTGEPNGPDGEVALDIEIAGAIAPAAKIAVYFAPNSDAGFIQAVNAAVTDKTNQPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA S +V GG+ L PG + ISISWGGPEAIWQAQS---------AQAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSSYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E TW + A GGG+S L+ P +QQG+ + L + R PDV +A P TGY++ SEVTWNDE--------------------ASGGGAGGGGVSALFDLPAWQQGLKVARADGSTTPL----------------AKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + +MGGTSAVAP +AA+ A +N+ G NP LY H R +NG Y G ++ GLG+ N +LA SVAGTP-AVMGGTSAVAPLWAALIARINAANGASAGWINPVLY-----KHPGALRDITKGSNGT--YAAASG--WDACTGLGSPNGAQLA
Show aligned area	115358052	Burkholderia ambifaria AMMD	peptidase S8 and S53, subtilisin, kexin, sedolisin	579	2e-23	0.25	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T + + LK R L QLA VN + ++ YLT +QF A + + A + Y R + + A N LL+ G T+ AF +L ELAAGETTDIVVSLKLRNAAQLKQLAHDVNRPGNAHYRQYLTHEQFLAGYAPTEAQVKSVVDYLRKSGFVNIDVAPNRLLVSAHGTAGTVKTAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF Y G+ + ++P + + +V+G+ N+ A+ L + A+ + L A + + K++ AT AG TVGII+ G V ++ F FEYAGRSGFANASTAQVPHALGDVVGSVLGLQNVARARPMLRIGNVAKPQALAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVSQTLQDLRQF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPR----AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNR G T KT G T DD D + D + + K+ Y A + + G AF A ++N A +++S G E D N TSSNGYGTVTTQTVKTNGTGTSGSYSDDQDGQGEWDLDSQSIVGSAGGQVGKLVFYMADLNAAGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANA DHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQH D L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G DGTL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGGNYTVSWPAASPHVLAIGGTTLYTTSAGA------FSNETVWNEGLDGNGK--- PLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVA A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS A --------------LWATGGGVSSILPAPSWQSG-----------------------------SNRQLPDVSFDAAQGTGAYIYNYGQ-LQQIGGTSLAA PQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ P F A + + +G YA ++ S R D + NNG Y G + G G++N L + Q PIFTGFWARLLAANGTGLGFPAGNFYADIPSNPS-LVRYDVVSGNNGYQGYGYSAGSGRDLTTGFGSLNIANLNKLIQ
Show aligned area	70606919	Sulfolobus acidocaldarius DSM 639	hypothetical protein Saci_1147	1275	2e-23	0.31	0.44
DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLT----PLYGDIMNTLLAQGAIQGISTFVASGD D ETALD E A +AP AK+ + + S A + +S+SWGLSEN+ + + P Y ++ A G +GI+ F +SGD DIETALDVEAAHAMAPYAKINLVVSSDSGPTLYAAVDYVVTQKLGDVVSMSWGLSENLFAASGFYYFINGQPFPNY-PYLDYYFALGTAEGITFFASSGD TGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQ TGAYG +L+ A FPA SP+VTA GG+TL + S E W Y ++ T +SGGG S + P YQ TGAYGDSLTTYGG-----ASFPATSPFVTAVGGTTLYL--------SSGKAYETAWS---VLPQYFEYAG------------TVSSGGGYSTFFPRPWYQ QGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTD GV +N+ S R PDV A+A+P TG++I S E++GGTS +P +A M A + S + +GL NP LY + + DGV--INS-----------------------SFRAVPDVAADANPYTGFNITVLGSE-EIIGGTSLASPLWAGMLADIISQLGRPIGLLNPILYWIYKNP HSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ T N + +PG YN GLGT N +L + Q ALYQESFHQITLGYNGEFYAKPG--YNLVTGLGTPNVGELLNAIQ
Show aligned area	116619713	Solibacter usitatus Ellin6076	kumamolisin	515	2e-23	0.28	0.41
IRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQT + + G VA +N+AF L+ R + A +P V VVGV L T+ + T + + A GAGQT VMLSGTVANMNEAFGTQLRLYRCPHGIFRSRTGALLVPANVGN---IVVGVFGLDTRPQAATRFRRLLAVGPRAAGDTSYTPEAVAKLYGFPAGNGAGQT VGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATV-MDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAEN--RASSLSL V II G TA + ++++ G+ T GG + + +D E LD E G IAP A + VY A +D G+LDA TTA ++ + S +S+ VAIIELGGGYRTADLNTYFQKLGIATPSVTAAGVDGGLNQPAGDPNSADGEVLLDIEVVGAIAPGAHIVVYFAPNTDQGFLDAITTAVHDSVHKPSVVSI SWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRER SWG E+ LT + A+ G++ ASGD G+ ++ A DFPA SP V GG+ L + VT+E SWGGPESSW----TAQALTQF-----DQAFQDAAVMGVTVCCASGDDGS-----ADGVADGAAHVDFPASSPNVLGCGGTRLESN-------AGKVTKEV TWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK W ASGGG+S + P YQ G + N+ + GR PDV +ADP TGY IY VWNA---------------------GPGNGASGGGVSETFPLPSYQVGANVPVSVNSTGF-----------------KGRGVPDVSGDADPGTGYQIYVD NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLG + GGTSAVAP +AA+ A++N + +G N +LY+ A+ + LD + + Y G PG ++ GLG GRD-AVFGGTSAVAPLWAALIAILNQQTGKPVGRINDKLYSAAKAKKA---LLDITSGDNGAYKAG-PG--WDPCTGLG
Show aligned area	172062849	Burkholderia ambifaria MC40-6	peptidase S53 propeptide	579	2e-23	0.25	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A +T + + LK R L QLA VN + ++ YLT +QF A + + A + Y R + + A N LL+ G T+ AF +L ELAAGETTDIVVSLKLRNAAQLKQLAHDVNRPGNAHYRQYLTHEQFLAGYAPTEAQVKSVVDYLRKSGFVNIEVAPNRLLVSAHGTTGTVKTAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF Y G+ + ++P + + +V+G+ N+ A+ L + A+ + L A + + K++ AT AG TVGII+ G V ++ F FEYAGRSGFANASTAQVPHALGDVVGSVLGLQNVARARPLLRIGNVAKPQALAAGTATGHYPKEFPGLYNATGVPTAAGVTVGIITIGGVSQTLQDLRQF WRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPR----AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNR G T KT G T DD D + D + + K+ Y A + + G AF A ++N A +++S G E D N TSSNGYGTVTTQTVKTNGTGTSGSYSDDQDGQGEWDLDSQSIVGSAGGQVGKLVFYMADLNAAGNTGLTQAFNRAVSDNTAKVINVSLGWCET---DANA DHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQH D L D + A QG + V+SGD G Y N +PA SP V A GG+TL A + E W + G DGTL-----DAEEQIFTTAAAQGQTFSVSSGDEGVYECNNRGYPDGGNYTVSWPAASPHVLAIGGTTLYTTSAGA------FSNETVWNEGLDGNGK--- PLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVA A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS A --------------LWATGGGVSSILPAPSWQSG-----------------------------SNRQLPDVSFDAAQGTGAYIYNYGQ-LQQIGGTSLSA PQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ P F A + + +G YA ++ S R D + NNG Y G + G G++N L + Q PIFTGFWARLLAANGTGLGFPAGNFYADIPSNPS-LVRYDVVSGNNGYQGYGYSAGSGRDLTTGFGSLNIANLNKLIQ
Show aligned area	78061222	Burkholderia sp. 383	peptidase S8 and S53, subtilisin, kexin, sedolisin	538	3e-23	0.29	0.42
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G + AF V L+ + + P LP + + AV+G+ + A+ P K + F AS GAG VVVLSGTIQQFEAAFGVKLERFEHQSIGQYRGRSGPIALPDDLGDAVTAVLGLDSRPQARPHFRLRPP-FKPARGGAAGVTFTPIQLASLYGFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + II G AA I+ ++R G+ T L G GD S D E ALD E AG IAP AK+ VY A SD G++ A A ++ N+ S QCIAIIELGGGYRAADIQQYFRGLGITTPPTLVDVNVGTGRNTPTGDPSGPDGEVALDIEIAGAIAPAAKIAVYFAANSDAGFIQAVNAAVSDTTNKPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + ISISWGGPEAIWQTQS---------AQAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E TW + A GGG+S L+ P +QQG+ + S P + R PDV +A P TGY++ SEVTWNDE--------------------AAGGGAGGGGVSTLFDLPAWQQGLT----------VARADGSSAP------LAKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMN + +MGGTSAVAP +AA+ A +N SIAGTA-TVMGGTSAVAPLWAALIARIN
Show aligned area	126457317	Burkholderia pseudomallei 1106a	kumamolisin	529	3e-23	0.28	0.42
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ +Y G+ + LP ++ + AV+G+ + A+ P L A+ + A+ LVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDIT-----LPDELHGIVTAVLGLDDRPQARPHFRLRPT---FLPARAPAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L + G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQQYFGGLGLARQPKLVDVSVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T +++L A G++ ASGD G+ L + + DFPA SP+V A GG+ L PG TNRPSVVSISWGAAEAN---------WTSQSIQAFDSVLQSAAALGVTVCAASGDDGS-NDGLQDGTN----HVDFPASSPYVLACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV +A P QGIR--SEVVWNDE--------------------AAGGGATGGGVSAVFDVPQWQSGLSAT---------LAQGGGASP------LAKRGVPDVAGDASP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY+++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + +NG Y PG ++ GLG+ N K+ ATGYEVFVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHDI-----SVGDNGA--YAATPG--WDACTGLGSPNGAKV
Show aligned area	187919482	Burkholderia phytofirmans PsJN	Peptidase S53 propeptide	519	5e-23	0.27	0.44
IRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRL--PKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQV-KHLTAKRSPTKFLKQYHASNLATSGQQG + + G +A AFAV L+ +H QF + + P + ++AV+G+ + A+ + P Q + +P + YH G VLLSGTIAQFQDAFAVKLEHYEHHTSG-QFRGRTGTISVPDDLHGVVQAVLGLDDRPQARPHFRIRPPFQAARGHQVSFTPPQLASLYHFPQ-----GDG AGQTVGIISFGHVPTAA-IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRA GQ VGII G A+ +K ++ GV + ++++ + GD + D E LD E G IAP A++ VY + SD G++DA + A + N+ GGQCVGIIELGGGYNASDLKSYFASLGVASP-KVKSVGVDQGSNQPTGDPNGPDGEVTLDIEIVGAIAPGAEIAVYFTQNSDAGFIDAVSRAVHDTTNKP SSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVN S +S+SWG E+ T N++L A G++ ASGD+G+ + G + DFPA SP+V A GG++L T + SVISISWGGPESN---------WTSQSLQAFNSVLQSAATLGVTVCAASGDSGS------SDGSGSGDQVDFPASSPYVLACGGTSLTASGT-------S VTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGY ++ E W A+GGG+S+ + P +Q+G++ +T +K L GR PDV +A P+TGY ISHEAVWND---------------------GAQGGATGGGVSQAFPVPVWQKGLSATSTKGGKKAL----------------GGRGVPDVAGDASPVTGY DIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + + ++GGTSAVAP +AA+ A +N+ + Q G NP+LY + T N + PG ++ GLG+ N +K+A SVLIDGTQ-TVVGGTSAVAPLWAALIARINAAKGQPAGFINPKLYKATGA-------CNDITQGNNGSFAASPG--WDACTGLGSPNGQKVA
Show aligned area	186473846	Burkholderia phymatum STM815	peptidase S53 propeptide	519	6e-23	0.25	0.43
VKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG--LLIRVKGHVATINKAFAVN V + +T+ + +VL+ + + +Q+ + + + LT ++ +FG ++L + F A H + + + + G + +AF V VAQCDPSETIEVVVVLRRKNEQQFAQMMKTIEAGAAGARP--LTREELEQRFGALPEDIAKL-KAFAAQHGLSVVREDASARTVVLSGRIEQFQQAFDVQ LKTARYHGK-KIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGH-VPTAAI L+ + + + A +P ++ + AV+G+ + A+ + P Q +S + F AS G+GQ +GI+ G TA + LQHYEHQSMGRFRGRTGAISVPDELHGVVTAVLGLDDRPQARPHFRIRPPFQPAR---AQSASSFTPLQLASLYRFPQGDGSGQCIGIVELGGGYRTADL KHFWRQAGV--PTTGRLETKTTGGATVMD-NGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASSLSLSWGLSENILRDLN ++ GV P + +G D NG D E LD E AG +AP A + VY SD G++DA + A + N+ S +S+SWG E+ DSYFSSLGVGSPKVVAVGVDQSGNQPTGDPNGPDG--EVTLDIEIAGALAPAATIAVYFTTNSDAGFIDAVSQAVHDRTNQPSVISISWGAPES------ RDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQ + T +N +L A G++ ASGD+G+ S+ DFPA SP+V A GG++L G V E W ---MWTAQSMKALNDVLQSAAAIGVTVCAASGDSGS-----SDGVGDGRDHVDFPASSPYVLACGGTSL-------QGSGRTVAHEVVWND--------- HPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAV A+GGG+S + P +Q+G++ ++ LT GR PDV +A P+TGYD+ + ++GGTSAV ------------GSNGGATGGGVSGAFPVPAWQEGLSTSAAQGGQRALT----------------GRGVPDVAGDASPLTGYDVIVDGNN-TVIGGTSAV APQFAAMAAVMNSDRSQRMGLWNPQLY AP +AA+ A +N + +G NP+LY APLWAALIARINGAKGAPVGFVNPKLY
Show aligned area	83716631	Burkholderia thailandensis E264	serine protease, kumamolysin	622	7e-23	0.27	0.41
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ RY G+ + LP ++ + AV+G+ + A+ P A+ + + A+ LVVLTGTIAQFEAAFGVKLERFEHRTVGRYRGRTGDIT-----LPDELRDVVTAVLGLDDRPQARPHFRLRPT---FQPARGAAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQRYFSGLGLAQQPKLVDVNVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATLAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T N +L A G++ VASGD G+ L + + DFPA SP+ A GG+ L PG TNRPSVVSISWGAAEAS---------WTSQSIQAFNRVLQSAAALGVTVCVASGDDGS-NDGLQDGAN----HVDFPASSPYALACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV +A P QGIR--SEVVWNDE--------------------AAGGGATGGGVSTVFDAPQWQSGLSAT---------LARGGGAAP------LAKRGVPDVAGDASP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + N Y PG ++ GLG+ + K+ ATGYEVLVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHD-------VSVGENGAYAATPG--WDACTGLGSPDGAKV
Show aligned area	116623072	Solibacter usitatus Ellin6076	peptidase S8 and S53, subtilisin, kexin, sedolisin	951	8e-23	0.27	0.42
QTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLL-IRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRL Q L+ L A S + +LTP+Q+ +FG S+ +++T + +LQ TA G + + G + +AF V++ +G+ + P L QQADLANLLAAQQDPASPEYHHWLTPEQYADRFGASADDVAKITAWLAQHNLQVTAVGRGRMSVTFTGTAGDVEQAFQVSMHRYSVNGRNHFANTAEPSL PKQVAQPIRAVVGVTN-LMIAKSLTTKSPAQVKHLTAK----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETK P + IR++ G+ + LM +S+ ++ + ++ +P Y+ L +G G GQ + I V A I+ F + G T + + PAAMEPAIRSIHGLHDFLMKPRSVVHRAAVDPNYTSSSGNHYLAPDDIGTIYNVKALWNAGYDGTGQKIAIAGQTQVDVADIQKFRAKFGQTTP---DPQ TTGGATVMDNGDDSDD--ETALDAEQAGTIAPRAK-VRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQG D G DD E LD E AG +AP+A + VY+ +D+ +DA A +N A LS+S+GL E + L D LL M T Q MMLVPNTKDPGVSKDDLGEADLDLEWAGAVAPQATLLYVYS---NDV--MDAVLYAIDQNLAPVLSVSYGLCEP--QTLKSDMLL-------MQTWAQQA AIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEEL---TA QG++ A+GD+G S + D PAD P VT GG+T + A G N T + G +I + + A NAQGMTWINAAGDSGGADCVTGSSGNGAALAVDSPADIPEVTGIGGTTF----SEAAGQYWNATNSASGGS----------ATAYIPETVWNDSTSGSPA ASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPI-TGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMN---- A GGG S ++ P +Q G+ GV P +G RN PD+ NA GY +YS + GGTSA P FA + A++N AGGGGASTVFTQPTWQTGL-GV-------------PSNG---------ARNVPDISLNASAEHDGYLVYSGGQ-LSVYGGTSAGTPAFAGITALLNHYLV ---SDRSQRMGLWNPQLYALAQTDHSPFTRLDAATN-----------NGNLYYVGQP-GKVYNQAAGLGTVNFEKLARSYQ + + +G NP+LYALAQ F + A N N G P G+ Y+ A+GLG+++ L ++ ATGAQNAAGVGNVNPRLYALAQAGAGVFHDVTAGDNIITVTCGQRARNCTPGTYGYPAGQGYDLASGLGSIDAYNLVTTWH
Show aligned area	76817289	Burkholderia pseudomallei 1710b	kumamolisin	577	8e-23	0.27	0.42
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ +Y G+ + LP ++ + AV+G+ + A+ P L A+ + A+ LVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDIT-----LPDELHGIVTAVLGLDDRPQARPHFRLRPT---FLPARAPAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L + G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQQYFGGLGLARQPKLVDVSVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T +++L A G++ ASGD G+ L + + DFPA SP+V A GG+ L PG TNRPSVVSISWGAAEAN---------WTSQSIQAFDSVLQSAAALGVTVCAASGDDGS-NDGLQDGTN----HVDFPASSPYVLACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV +A P QGIR--SEVVWNDE--------------------AAGGGATGGGVSAVFDVPQWQSGLSAT---------LAQGGGASP------LAKRGVPDVAGDASP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY+++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + +NG Y PG ++ GLG+ + K+ ATGYEVFVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHDI-----SVGDNGA--YAATPG--WDACTGLGSPDGAKV
Show aligned area	163841893	Renibacterium salmoninarum ATCC 33209	pseudomonapepsin precursor	597	9e-23	0.24	0.40
RLQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG-LLIRVKGHVATIN R+ H + ++ ++ + L P L L VN S ++ +LT ++ A+F + A + +A L A G + G+V+ + RVSHSQRLDAAPAQQQRTIKVSLAPHNVAILDALLANVNDPASPQYRHFLTSAEYAARFAPTQAEVDSVAAVLKAKGLSIDAVGPGNHYVSASGNVSQLQ KAFAVNLKTARYHGKKIQFSKQAP--RLPKQVAQPIRAVVGVTNL-MIAKSLTTKSP-------AQVKHLTAKRS-------PTKFLKQYHASNLATSGQ F NL R F+ ++P+ +A I V G+T+ I + + K+P + K +T K S P + Y+ ++++ + Q NLFKTNLSQYRDSQTGTDFTGADSDVKVPQSLAGLITDVSGLTDEGKILRPASYKAPVDAATLQTEAKAVTDKGSGVKGGFTPKELNSGYNTASISGAAQ QGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSL GAGQT+ ++ F + + + Q + + GG D G E LD + +AP+A + Y A +D +D +T +N+AS + -GAGQTIALVEFSGHKQSHVTTYNTQYNISAATLQDVNVDGGPGTPDEGQG---EVGLDIQVLHAVAPKASILNYQAPNTDAADIDLYTAIINDNKASIV SLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTR S SWG +EN + H+ ++ + Q QG + ASGD GA + + A + D P+ P VT GG+ L I SSSWGNAEN---QSTQSHITA------LSNIFKQATAQGQTILSASGDHGASDDWSNNNDAK--LTVDSPSSDPNVTGVGGTRLSIDSNTG--------- ERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIY W G+ + Y + + A+GGG+S + P +Q G AGVNT R+ PD+ + A Y IY --AWAGEAVWNDYVKSG----------DTWRGATGGGVSTFFARPSWQTG-AGVNTSQKRQ----------------------VPDISSAAAEFQ-YSIY SKN---------SGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLW--NPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKV-----YNQAAGLGTVN S+N GW GTSA AP A A++++ +G NP +Y A + S F + + TN+ VG+ +++A G G+ N SENYDSNGNDLGEGWSASAGTSAAAPLNAGFLALVSNQGGGSVGFGNVNPAIYKAAAANPSAFHDITSGTNS----IVGKSSSYAVTAGFDKATGWGSPN F F F
Show aligned area	53722583	Burkholderia pseudomallei K96243	kumamolisin	529	9e-23	0.27	0.42
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ +Y G+ + LP ++ + AV+G+ + A+ P L A+ + A+ LVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDIT-----LPDELHGIVTAVLGLDDRPQARPHFRLRPT---FLPARAPAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L + G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQQYFGGLGLARQPKLVDVSVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T +++L A G++ ASGD G+ L + + DFPA SP+V A GG+ L PG TNRPSVVSISWGAAEAN---------WTSQSIQAFDSVLQSAAALGVTVCAASGDDGS-NDGLQDGTN----HVDFPASSPYVLACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV +A P QGIR--SEVVWNDE--------------------AAGGGATGGGVSAVFDVPQWQSGLSAT---------LAQGGGASP------LAKRGVPDVAGDASP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY+++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + +NG Y PG ++ GLG+ + K+ ATGYEVFVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHDI-----SVGDNGA--YAATPG--WDACTGLGSPDGAKV
Show aligned area	126445010	Burkholderia pseudomallei 668	serine protease, kumamolysin	529	2e-22	0.27	0.42
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ +Y G+ + LP ++ + AV+G+ + A+ P L A+ + A+ LVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDIT-----LPDELHGIVTAVLGLDDRPQARPHFRLRPT---FLPARAPAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L + G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQQYFGGLGLARQPKLVDVSVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T + +L A G++ ASGD G+ L + + DFPA SP+V A GG+ L PG TNRPSVVSISWGAAEAN---------WTSQSIQAFDRVLQSAAALGVTVCAASGDDGS-NDGLQDGTN----HVDFPASSPYVLACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV +A P QGIR--SEVVWNDE--------------------AAGGGATGGGVSAVFDVPQWQSGLSAT---------LAQGGGASPLV------KRGVPDVAGDASP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY+++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + +NG Y PG ++ GLG+ + K+ ATGYEVFVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHDI-----SVGDNGA--YAATPG--WDACTGLGSPDGAKV
Show aligned area	126446539	Burkholderia mallei NCTC 10247	serine protease, kumamolysin	529	3e-22	0.27	0.42
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ +Y G+ + LP ++ + AV+G+ + A+ P L A+ + A+ LVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDIT-----LPDELHGIVTAVLGLDDRPQARPHFRLRPT---FLPARAPAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L + G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQQYFGGLGLARQPKLVDVSVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T +++L A G++ ASGD G+ L + + DFPA SP+V A GG+ L PG TNRPSVVSISWGAAEAN---------WTSQSIQAFDSVLQSAAALGVTVCAASGDDGS-NDGLQDGTN----HVDFPASSPYVLACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV + P QGIR--SEVVWNDE--------------------AAGGGATGGGVSAVFDVPQWQSGLSAT---------LAQGGGASP------LAKRGVPDVAGDVSP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY+++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + +NG Y PG ++ GLG+ + K+ ATGYEVFVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHDI-----SVGDNGA--YAATPG--WDACTGLGSPDGAKV
Show aligned area	124381732	Burkholderia mallei NCTC 10229	serine protease, kumamolysin	529	3e-22	0.27	0.42
LIRVKGHVATINKAFAVNLK------TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSG L+ + G +A AF V L+ +Y G+ + LP ++ + AV+G+ + A+ P L A+ + A+ LVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDIT-----LPDELHGIVTAVLGLDDRPQARPHFRLRPT---FLPARAPAVTYTPPQLAALYDFPP QQGAGQTVGIISFG--HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE- GAGQ + I+ G + P A I+ ++ G+ +L + G GD S D E ALD E AG IAP A + VY A+ SD G++ A A + GDGAGQCIAIVELGGGYRP-AEIQQYFGGLGLARQPKLVDVSVGAGRNAPTGDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDT -NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG NR S +S+SWG +E T +++L A G++ ASGD G+ L + + DFPA SP+V A GG+ L PG TNRPSVVSISWGAAEAN---------WTSQSIQAFDSVLQSAAALGVTVCAASGDDGS-NDGLQDGTN----HVDFPASSPYVLACGGTRLDA----LPG ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP + E W + A+GGG+S ++ P++Q G++ A G + P + R PDV + P QGIR--SEVVWNDE--------------------AAGGGATGGGVSAVFDVPQWQSGLSAT---------LAQGGGASP------LAKRGVPDVAGDVSP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TGY+++ + +MGGTSAVAP +AA+ A +N+ G NP+LY A H + +NG Y PG ++ GLG+ + K+ ATGYEVFVAGTS-TVMGGTSAVAPLWAALVARINAAAGSPAGWINPKLYRNAGALHDI-----SVGDNGA--YAATPG--WDACTGLGSPDGAKV
Show aligned area	83717912	Burkholderia thailandensis E264	serine protease	562	4e-22	0.24	0.39
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRA-CHLQATAANNGLLIRVKGHVATINKAFAVNLKT ++A + + + LK R + L +A V+ S ++ Y+T QF + + + A ++ Y R + A N +L+ +G T+ +AF +L ELASGEATHVVVSLKLRNAEQLKAVARNVSDPHSSQYRQYITSAQFLSNYAPTKAQVKQVVDYLRKNGFVDIRVAPNRMLVSARGSAGTVKQAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTT-KSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHF Y G+ + ++P+ + + +V+G+ N+ A+ LT + A+ L + + + ++ A AT A TVGI++ G V A ++ F FEYAGRAGFANASTAQVPRALGDIVGSVLGLQNVARARPLTKIGAIAKPLSLASGTATGHYPSEFPALYNATGVPNAANTTVGIMTIGGVSQALSDLQQF WRQAGVP--TTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPR----AKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDL G P +T ++T +GG D DD + + D + + ++ Y A S + G AF A ++N A +++S G E D TSANGYPDVSTQTVQTNGSGG----DYSDDQEGQGEWDLDSQSIVGAAGGQVGQLIFYMADLSASGNTGLTQAFNQAVSDNTAKVINVSLGWCET---DA NRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYH N D L+ + Q QG + V+SGD G Y N +PA SP V A GG+TL + A + E W + G NADGTLSA-----EEQIFTQAVAQGQTFAVSSGDEGVYECNNRGYPDGSNYSVSWPASSPHVLAIGGTTLYTSSSGA------FSNETVWNEGLDGNGK- QHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSA A+GGG+S + P +Q G S R PDV +A TG IY+ + +GGTS ----------------LWATGGGVSTILPNPSWQSG-----------------------------SNRKLPDVSFDAAQSTGAYIYNYGQ-LQQIGGTSL VAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ AP F A + S +G + Y T H+ R D + NNG Y K ++ G G++N L + Q SAPIFTGFWARLLSANGASLGFPAARFYHSIPT-HASLVRYDVTSGNNGYQGYGFTASKGWDYPTGWGSINISNLNQLIQ
Show aligned area	27375805	Bradyrhizobium japonicum USDA 110	peptidase	401	8e-22	0.30	0.43
GQQGAGQTVGIISFGHV-----PTAA------IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDA G+ GAGQ + II + PT A ++ F+++AG+P GGA ++D E LD E AG IAP A++ VY A + G++DA GETGAGQCIAIIELNDIDQKGHPTGAGYKTSDLRTFFKKAGIPMPQIAPASVDGGAN-KPGHSEADGEVVLDIEVAGAIAPGARIVVYFAPNTTNGFIDA FTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLP A A + S +S+SWG E D + + D +N + A G++ VASGD G+ + P ADFPA SP+ A GG+ L VKAAVHDAARKPSVISISWGGPE--------DEDGSQQFVDGLNEAIRDAAAMGVTVCVASGDNGSADMG-EDWDGKP--HADFPASSPFALACGGTNLK IKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYP AP + +E W G A GGG+S ++ P YQ A PKS + GR P -----APNGHI---QEVVWNG---------------------GTQGGAGGGGVSVVFPRPAYQA--------------HAHVPKSP-----SHSVGRGVP DVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQR----MGLWNPQLYALAQTDHSPFTRLDAATNN--GNLYYVGQPGKVYNQAAG DV +ADP TGY I+ G +GGTSAVAP A + A +N +++ +G NP +Y A F + N+ G+L+ + + G ++ +G DVAGDADPATGYQIFLNGVG-TTIGGTSAVAPLMAGLIARINEATTKKFGKTVGFINPLIY--ASHAQGVFRDITVGNNDITGDLHGMYKAGPGWDACSG LGTVN LG N LGVPN
Show aligned area	53722755	Burkholderia pseudomallei K96243	sedolisin	582	8e-22	0.24	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRA-CHLQATAANNGLLIRVKGHVATINKAFAVNLKT +VA + + + LK R + L +A VN S ++ Y+T QF A + + A ++ Y R + A N +L+ +G T+ +AF +L EVASGEATHVVVSLKLRNAEQLKAVARNVNDPHSSQYRQYITSAQFLANYAPTEAQVKQVIAYLRKNGFVDIHVAPNRMLVSARGTAGTVKQAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLT-----TKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-- Y G+ + ++P+ + + +V+G+ N+ A+ LT K A P++F Y+A+ + T+ A TVGII+ G V A FEYAGRAGFANASTAQVPRALGDIVGSVLGLQNVARARPLTKIGAIAKPLALASGTATGHYPSEFPALYNATGVPTA----ANATVGIITIGGVSQALSD IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ--AGTIAPRAKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDL ++ F P +T G + + E LD++ ++ Y A + G AF A ++N A +++S G E D LQQFTSANSYPDVSTQTIQTNGSGGNYSDDQEGQGEWDLDSQSIVGAAGGQLGQLIFYMADLDASGNTGLTQAFNQAVSDNAAKVINVSLGWCET---DA NRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYH N D L+ + Q QG + V+SGD G Y N +PA SP V A GG+TL + A + E W + G NADGTLSA-----EEQIFTQAVAQGQTFAVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVLAIGGTTLYTTSSGA------FSNETVWNEGLDGNGK- QHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSA A+GGG+S + P +Q G S R PD+ +A TG IY+ + +GGTS ----------------LWATGGGVSTILPNPSWQSG-----------------------------SHRKLPDISFDAAQSTGAYIYNYGQ-LQQIGGTSL VAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ AP F A + S +G + Y T H+ R D + NNG Y + ++ G G++N L + Q SAPIFTGFWARLLSANGTGLGFPAARFYHSIPT-HASLVRYDVTSGNNGYSGYGYKASTGWDYPTGWGSINISNLNQLIQ
Show aligned area	172064179	Burkholderia ambifaria MC40-6	peptidase S53 propeptide	533	8e-22	0.29	0.41
LIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAP-RLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAG ++ + G + AF+V L+ + + P LP ++ + AV+G+ + A+ P A + F AS GAG VVVLSGTIQQFEAAFSVKLERFEHRAIGQYRGRSGPIALPDELGDVVTAVLGLDSRPQARPHFRLRPPFRPARGA--TSVTFTPPQLASLYGFPAGDGAG QTVGIISFGHVPTAA-IKHFWRQAGV--PTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASS Q + I+ G A I+ ++R G+ P T TG T + + D E ALD E AG IAP AK+ VY A SD G++ A A + NR S QCIAIVELGGGYRATDIQQYFRGLGIDKPPTVVDVNVGTGRNTPTGDANGPDGEVALDIEIAGAIAPAAKIAVYFAPNSDAGFIQAVNAAVTDKTNRPSV LSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVT +S+SWG E I + + N +L A QGI+ ASGD+G+ G L + + DFPA SP+V GG+ L PG + ISISWGGPEAIWQAQS---------AHAFNRVLQAAAAQGITVCAASGDSGS-GDGLQDGAD----HVDFPASSPYVLGCGGTQLDA----LPGQGIR-- RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E TW + A GGG+S ++ P +Q+G+ A+ S L + R PDV +A P TGY++ SEVTWNDE--------------------AAGGGAGGGGVSTMFDVPAWQKGLT-----------VALADGSSRPL-----AKRGVPDVAGDASPQTGYEV YSKNSGWELMGGTSAVAPQFAAMAAVMN---SDRSQRMGLW-NPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA S +MGGTSAVAP +AA+ A +N S + W NP LY H R +NG Y G ++ GLG+ + KLA -SIAGTPAVMGGTSAVAPLWAALIARINAAASAAAGASAGWINPVLY-----KHPGALRDITKGSNGT--YAAASG--WDACTGLGSPDGAKLA
Show aligned area	76817576	Burkholderia pseudomallei 1710b	sedolisin	582	9e-22	0.24	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRA-CHLQATAANNGLLIRVKGHVATINKAFAVNLKT +VA + + + LK R + L +A VN S ++ Y+T QF A + + A ++ Y R + A N +L+ +G T+ +AF +L EVASGEATHVVVSLKLRNAEQLKAVARNVNDPHSAQYRQYITSAQFLANYAPTEAQVKQVVAYLRKNGFVDIHVAPNRMLVSARGTAGTVKQAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLT-----TKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-- Y G+ + ++P+ + + +V+G+ N+ A+ LT K A P++F Y+A+ + T+ A TVGII+ G V A FEYAGRAGFANASTAQVPRALGDIVGSVLGLQNVARARPLTKIGAIAKPLALASGTATGHYPSEFPALYNATGVPTA----ANATVGIITIGGVSQALSD IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ--AGTIAPRAKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDL ++ F P +T G + + E LD++ ++ Y A + G AF A ++N A +++S G E D LQQFTSANSYPDVSTQTIQTNGSGGNYSDDQEGQGEWDLDSQSIVGAAGGQLGQLIFYMADLDASGNTGLTQAFNQAVSDNAAKVINVSLGWCET---DA NRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYH N D L+ + Q QG + V+SGD G Y N +PA SP V A GG+TL + A + E W + G NADGTLSA-----EEQIFTQAVAQGQTFAVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVLAIGGTTLYTTSSGA------FSNETVWNEGLDGNGK- QHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSA A+GGG+S + P +Q G S R PD+ +A TG IY+ + +GGTS ----------------LWATGGGVSTILPNPSWQSG-----------------------------SHRKLPDISFDAAQSTGAYIYNYGQ-LQQIGGTSL VAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ AP F A + S +G + Y T H+ R D + NNG Y + ++ G G++N L + Q SAPIFTGFWARLLSANGTGLGFPAARFYHSIPT-HASLVRYDVTSGNNGYSGYGYKASTGWDYPTGWGSINISNLNQLIQ
Show aligned area	126445423	Burkholderia pseudomallei 668	sedolisin	562	1e-21	0.24	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRA-CHLQATAANNGLLIRVKGHVATINKAFAVNLKT +VA + + + LK R + L +A VN S ++ Y+T QF A + + A ++ Y R + A N +L+ +G T+ +AF +L EVASGEATHVVVSLKLRNAEQLKAVARNVNDPHSSQYRQYITSAQFLANYAPTEAQVKQVVAYLRKNGFVDIHVAPNRMLVSARGTAGTVKQAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLT-----TKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-- Y G+ + ++P+ + + +V+G+ N+ A+ LT K A P++F Y+A+ + T+ A TVGII+ G V A FEYAGRAGFANASTAQVPRALGDIVGSVLGLQNVARARPLTKIGAIAKPLALASGTATGHYPSEFPALYNATGVPTA----ANATVGIITIGGVSQALSD IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ--AGTIAPRAKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDL ++ F P +T G + + E LD++ ++ Y A + G AF A ++N A +++S G E D LQQFTSANSYPDVSTQTIQTNGSGGNYSDDQEGQGEWDLDSQSIVGAAGGQLGQLIFYMADLDASGNTGLTQAFNQAVSDNAAKVINVSLGWCET---DA NRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYH N D L+ + Q QG + V+SGD G Y N +PA SP V A GG+TL + A + E W + G NADGTLSA-----EEQIFTQAVAQGQTFAVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVLAIGGTTLYTTSSGA------FSNETVWNEGLDGNGK- QHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSA A+GGG+S + P +Q G S R PD+ +A TG IY+ + +GGTS ----------------LWATGGGVSTILPNPSWQSG-----------------------------SHRKLPDISFDAAQSTGAYIYNYGQ-LQQIGGTSL VAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ AP F A + S +G + Y T H+ R D + NNG Y + ++ G G++N L + Q SAPIFTGFWARLLSANGTGLGFPAARFYHSIPT-HASLVRYDVTSGNNGYSGYGYKASTGWDYPTGWGSINISNLNQLIQ
Show aligned area	126456903	Burkholderia pseudomallei 1106a	sedolisin	562	1e-21	0.24	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRA-CHLQATAANNGLLIRVKGHVATINKAFAVNLKT +VA + + + LK R + L +A VN S ++ Y+T QF A + + A ++ Y R + A N +L+ +G T+ +AF +L EVASGEATHVVVSLKLRNAEQLKAVARNVNDPHSSQYRQYITSAQFLANYAPTEAQVKQVVAYLRKNGFVDIHVAPNRMLVSARGTAGTVKQAFNTSLVH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLT-----TKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-- Y G+ + ++P+ + + +V+G+ N+ A+ LT K A P++F Y+A+ + T+ A TVGII+ G V A FEYAGRAGFANASTAQVPRALGDIVGSVLGLQNVARARPLTKIGAIAKPLALASGTATGHYPSEFPALYNATGVPTA----ANATVGIITIGGVSQALSD IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ--AGTIAPRAKVRVYTAKFS---DIGWLDAFTTAFAENRASSLSLSWGLSENILRDL ++ F P +T G + + E LD++ ++ Y A + G AF A ++N A +++S G E D LQQFTSANSYPDVSTQTIQTNGSGGNYSDDQEGQGEWDLDSQSIVGAAGGQLGQLIFYMADLDASGNTGLTQAFNQAVSDNAAKVINVSLGWCET---DA NRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYH N D L+ + Q QG + V+SGD G Y N +PA SP V A GG+TL + A + E W + G NADGTLSA-----EEQIFTQAVAQGQTFAVSSGDEGVYECNNRGYPDGSNYTVSWPASSPHVLAIGGTTLYTTSSGA------FSNETVWNEGLDGNGK- QHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSA A+GGG+S + P +Q G S R PD+ +A TG IY+ + +GGTS ----------------LWATGGGVSTILPNPSWQSG-----------------------------SHRKLPDISFDAAQSTGAYIYNYGQ-LQQIGGTSL VAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAAT-NNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ AP F A + S +G + Y T H+ R D + NNG Y + ++ G G++N L + Q SAPIFTGFWARLLSANGTGLGFPAARFYHSIPT-HASLVRYDVTSGNNGYSGYGYKASTGWDYPTGWGSINISNLNQLIQ
Show aligned area	118473419	Mycobacterium smegmatis str. MC2 155	kumamolisin	550	1e-21	0.26	0.40
VKGHVATINKAFAVNLKTAR-YHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK-----RSPTKFLKQYHASNLATSGQQG V+G A + AF V++ R G++ S Q P +P +P+R+ V ++ + + ++HL A+ +P L Y+ LA G G VEGPPADMAAAFEVDIHDYRGRRGQEFYASPQQPSIP----EPVRSEVTEVGRILGYTPYRMNTPDLQHLPAEVPDRGLTPQLLLNTYNLRGLAEQGYTG AGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAK--------FSDIGWLDAFTTAFAE GQT+ I +F A + + +P R GG G ET +D + A IAP A+ V A+ + IG + KGQTIVIFAFDGFDQADLDTYADTFDLP---RFTPILVGGQPSTPRG-----ETTMDLQVAHAIAPDARKVVVNARPTVQGDGAYEKIGQMLEDADRQFP NRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY----GQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTF S S+ WG D L+T + + LA +G + F ASGD GQ+ S + I D A P +T GG+TL GAVWSFSIGWGC----------DKLITAADLAPVRSALAAAHTRGTTAFNASGDLAGLECKGGQDWSSAPGDDDIGLDSVASLPEITDVGGTTL------ APGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVAN + T + W + + + PL + +GGG+S L+ P +QQG + + A++ LT PD+ A ------STTADGAWLAE---QAWFDVPL------------SQGTGGGVSALFDRPDWQQGFSAPDDGGAQRRLT--------------------PDIAAV ADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMN----SDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFE ADP TG I N + GGTS AP +A +AAVMN ++ + +G NP LY +A+ +P T GN PG Y+ GLGT + E ADPFTGVKIVLNNQVL-VGGGTSQAAPLWAGIAAVMNQYLVANGGRAIGDLNPMLYQIARG--APLPAFRDVTLGGNAVATAGPG--YDLVTGLGTPDTE KLARS L ++ NLVKN
Show aligned area	91778133	Burkholderia xenovorans LB400	kumamolisin	519	2e-21	0.28	0.43
GHVATINKAFAVNLKTARYH-GKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS-LTTKSPAQ-VKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTV G +A AFAV L+ +H + + +P + + AV+G+ N A+ + P Q + +P + YH G G+ V GTIAQFQNAFAVKLEHYEHHTAGQFRGRTGTISVPDDLHGVVEAVMGLDNRPQARPHFRIRPPFQPARGHQVSFTPPQLASLYHFPQ-----GDGGGECV GIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS--DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAE--NRASSLSL GII G TA +K ++ GV + G+ +GD + D E LD E G IAP AK+ VY + SD G++DA + A + N+ + +S+ GIIELGGGYDTADLKSYFASLGVASPTVKSVGVDQGSN-QPSGDPNGPDGEVTLDIEIVGAIAPGAKIAVYFTQNSDAGFIDAVSRAVHDTTNKPTVISI SWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRER SWG E+ T N +L A G++ ASGD+G+ A G + DFPA SP+V A GG+ L T +++ E SWGGPESN---------WTSQSLQAFNGVLQSAAALGVTVCAASGDSGS------SDGASGGDQVDFPASSPYVLACGGTNLTASGT-------SISHEA TWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK W ASGGG+SR + P +Q+G++ + + L SGR PDV +A P+TGY + VWND---------------------GAEGGASGGGVSRAFPVPAWQKGLSATASSGGKTAL----------------SGRGVPDVAGDASPVTGYSVLID NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + ++GGTSAVAP +AA+ A +N+ + Q G NP+LY +P D N N + G ++ GLG+ N +K+A GTQ-TVVGGTSAVAPLWAALIARINAAKGQPAGFINPKLY------RTPGVCNDITQGN-NGSFAASAG--WDACTGLGSPNGQKVA
Show aligned area	94969662	Acidobacteria bacterium Ellin345	serine protease, kumamolysin	553	3e-21	0.30	0.43
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENR--ASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY E +D E A +AP A + VY A ++ G A A + +S+SWG +E + D R L LL A +GI+ +SGD GAY EVTMDIEVAAALAPGAHLVVYMAPPTEQGLYKALDAAIHDTPPLVDVVSISWGEAELYVSDAYRKSL---------TQLLEDAAARGITVCASSGDNGAY GQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVA +++ + +FPA SP V A GG+T+ +++ GI +E W + G H AA+GGG+S + P +Q DDPPNQTLCV-----NFPASSPLVLACGGTTI---ASYSSGIQ----KEVVWNCGV--HGIH-----------------AATGGGVSEHFPLPTWQDA-- GVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPF K P +GYR GR PDV A ADP G +I + G TSAV P +AA+ A N +R G P+LY LA+++ SPF ----------------KLVPASANGYR-GRGVPDVAAVADPHNGCEILVRGIRCSSFG-TSAVVPFWAALIARCNQALGKRSGQIQPKLYELAKSESSPF TRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL A N +Y G +N GLG + +L R---AILEGDNFFYRAAAG--WNPCTGLGAPDGSRL
Show aligned area	15921996	Sulfolobus tokodaii str. 7	hypothetical protein ST1692	1177	4e-21	0.28	0.44
TKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS-DDETALDAEQAGTIAPRAKVRVYTAKFS T LK Y+A+ L T+G+ G T+GI+ F PT + +F + +P+ E K G + + E +LD E + +AP+A + +Y A TWLLKAYNATVLNTTGE---GYTIGILDFYGDPTIVQQLAYFDKIYNLPSPSSFEIKYIGPSCPFGGLLSGWNLEISLDVEVSHAMAPKASIILYVAN-P DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATG ++ E++ + LS SWG+ E+ + D N +L+T +Y MN A G+++GI+ ++GD G G + S P FP+ SP+VTA G NLPLPAVLAKIVQEDKVNVLSQSWGIPESEIVD-NPANLMT-VYE--MNLYYALGSLEGITFLASTGDVGGSGYSTS-----PIGSVTFPSTSPFVTAIG GSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRS G+T T+ I++N + +T + F Y + S GGIS L+ P YQ + NTY GTT-----TY---ITLNGSAYQTAWSNYGFIPYFTN--------------YGGSTGGISVLFVKPWYQFYIPTPNTYP---------------------Y GRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGL GR PD+ NA+ G + + L+GGTS +P FA + ++ + GL NP LY L + ++ T N+ +V + G YN GL GRMVPDISLNANLFPGIQVVFPGNITYLIGGTSEASPLFAGLLTLVMQKDNMTFGLINPLLYYLGEKYYN--EAYFPITFGYNIPWVAKYG--YNLVTGL GTVNFEKLA G N ++A GAPNIGEIA
Show aligned area	78062414	Burkholderia sp. 383	sedolisin-B	644	5e-21	0.24	0.40
HVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVN HV + + + + +VLK R L VN S S+ YLTP QF+A+F + A + + + +A T ++N LI G+ + + F + HVTPLELSQPLHVTVVLKNRNADQLDTFLRDVNQPGSASYHKYLTPAQFKARFSPTDAQVAAVVAHLKANGFSNITVSDNNTLIAADGNAGNVQRGFQAS LKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK---SPAQVKHLTAKRS---------PTKFLKQYHASNLATSGQQGAGQTVGIIS +K Y GK + + A +P + + +V+G+ N + L + S A ++ +K + PT F K Y AS L + TVGII+ IKRFNYRGKPVYANDSAALIPASLGPVVDSVLGLQNAAVPHRLLHRFAPSAAVEPNVVSKNATAGSQVGHQPTDFAKIYDASGLPAA----TNTTVGIIT FGHVPT--AAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSL +G + A + F + AG+ T G T+ D+GD E LD++ GT ++ Y+A +D A+ A +N+A+ + WGDMTQTIADLNTFTQNAGLATVNT-AVVAGGSGTLADDGDPG--EWDLDSQDIIGTSGGVKQLIFYSAINGDSNDSGLTDATLTAAYNKAVTDNKATVI SLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGS ++S GL E N D L + + Q QG V++GD G Y + S A PG + PA SP+V A GG+ NVSLGLDETA---ANSDGSLAA-----DDAVFKQAVAQGQVFSVSAGDAGVYQWSTSPQGA-PGYIGTYNGTSVKTTINLSKYSVSSPASSPYVVAVGGT TLPIKKTFAPGISVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSG +++ T TW G+ ++ +G L +P+ A+GGG+S P +Q G + ------------TLSTTGTTTWAGETVWNEGVAYADLDSNGNPVDNAVRIWATGGGVSAFETAPSWQTAALGSTV-----------------------TK RNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGL R PDV +A TG I +L+GGTS +P F A + S + +GL Y T+ S + + N + + Y + G ++ G RVLPDVAFDAAQATGAYIVINGQTNQLVGGTSLASPIFVGGWARVESANNNSLGLPTSAFYQGLPTNTSLLHDVTSGNNGYSSHGYTAKAG--WDDDTGF GTVNFEKLARS G+++F K++ S GSLDFAKVSAS
Show aligned area	78048290	Xanthomonas campestris pv. vesicatoria str. 85-10	kumamolisin-like protease	523	6e-21	0.27	0.41
LTPQQFRAKFGQSSATTSRLTRYFRACH---LQATAANNGLLIRVKGHVATINKAFAVNLK-----TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTN LT +F +F +SAT + F A + ++ A++G +I ++G V AF V+L+ RY G+ S +P+ + + AV+G+ LTRAEFSERFA-ASATDLQAVADFAARYGLTMEHAHADSGNVI-LEGTVQQCEAAFQVSLRDYVDGAMRYRGRTGPVS-----IPQTLGGIVTAVLGLDA LMIAKSL------TTKSPAQVKHLTAKRSPTKFLKQYHASNLAT----SGQQGAGQTVGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDN A++L T SP ++ S + QY LA G GQ +GII G A + ++ Q VP ++ G + RPQAQTLPSAPEATASSPPALQATAPAGSEDGPIMQYTPPQLAQLYGFPEHDGQGQCIGIIVLGGGYARAQMAAYFAQLRVPMPTLVDVLLPGATNTVSR GD-DSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVA G+ D+D E +D + AG IAP AK+ VY A +D G+L+A A AE+ +++SWG +E+ TP N A+ GI+ +A GNADADVEAQMDIQIAGAIAPGAKLVVYFAPNTDNGFLEAINAAIHDAEHSPGVIAISWGFTES---------QWTPQSRQAYNCAFQAAALMGITVCIA SGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTP +GD GA S PG+ FPA SP+V A GG+ L ++ + E+ W A GGG S + P AGDDGA-------SDGQPGLNVCFPASSPFVLACGGTRLQ--------VTADSATEQAW---------------------------ANGGGGESSFFARP KYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTS +Q KYL + + + R PDV ANAD TGY + S N +MGGTS AWQ------------KYLRITDARHQSRQL----GMRGVPDVAANADAQTGYYL-SINGQPAVMGGTS
Show aligned area	77748661	Xanthomonas axonopodis pv. citri str. 306	peptidase	523	5e-19	0.25	0.40
LTPQQFRAKFGQSSATTSRLTRYFRA--CHLQATAANNGLLIRVKGHVATINKAFAVNLK-----TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNL T +F +F +A + + + ++ A++G +I ++G V AF V+L+ RY G+ S +P+ + + AV+G+ FTRAEFSERFAAGAADLQAVADFAASYGLRIEHAHADSGSVI-LEGTVQQCEAAFQVSLRDYIDGAMRYRGRTGPVS-----IPQALGGIVTAVLGLDAR MIAKSLTTKS------PAQVKHLTAKRSPTKFLKQYHASNLAT----SGQQGAGQTVGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNG A++L + P ++ S + QY LA G GQ +GII G + ++ Q VP ++ G + G PQAQTLPSAPEASASLPPAIQPTAPADSRDGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYARDQMTAYFAQLRVPMPTLVDVLLPGATNAVSRG D-DSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVAS + D+D E +D + AG IAP AK+ +Y A +D G+L+A A AE+ +++SWG +E+ TP + A+ GI+ +A+ NADADVEAQMDIQIAGAIAPGAKLVMYFAPNTDNGFLEAINAAIHDAEHSPGIIAISWGFTES---------QWTPQSRQAYDCAFRAAALMGITVCIAA GDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPK GD GA S PG+ FPA SP+V A GG+ L ++ + E+ W A+ GGG SR + P GDDGA-------SDGQPGLNVCFPASSPFVLACGGTRLQ--------VTADSANEQAW---------------------------ASGGGGESRFFARPA YQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTS +Q + + + + L R PDV ANAD TGY + S N +MGGTS WQNNLRLTDAQHQSRQLRM----------------RGVPDVAANADAQTGYYL-SINGQPAVMGGTS
Show aligned area	126447458	Burkholderia mallei NCTC 10247	serine protease, subtilase family protein	798	8e-19	0.24	0.40
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANGFGDITVSANNKLIFAQGNASNAERGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK-SPAQ--------VKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L + +PA K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGI N D L + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------ SVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP +++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TLSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQ ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S STGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	121596647	Burkholderia mallei SAVP1	serine protease, subtilase family protein	766	9e-19	0.24	0.40
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANDFGDITVSANNKLIFAQGNASNAERGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK-SPAQ--------VKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L + +PA K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGI N D L + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------ SVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP +++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TLSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQ ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S STGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	15898960	Sulfolobus solfataricus P2	peptidase related protein	1077	1e-18	0.27	0.41
SRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVG--VTNLMIAKSLTTKSPAQVKHLTAKRS S+ R ++ AT+ N +I G V+ + KA +GK+ +P +P + V+G +T+L++ K T + Q A + SKTLSQLRQSNISATSYMN--VILASGTVSQLEKALNGKFYVYELNGKRFFEFFGSPVIPNAI------VIGTNITSLILNKPTTLYNVTQAVAYNALK- PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSD--DETALDAEQAGTIAPRAKVRVYTAK P++ L Y+ S L G G +GI+ F P ++ F +Q +P + G A +NG + E +LD E A IAP A + +Y A PSQLLYAYNISWLHAHNITGKGTAIGILDFYGNPYIQQQLQEFDKQYNIPNPPFFKIVPIG-AYNPNNGISTGWAMEISLDVEYAHVIAPDAGIVLYVAN FSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQ---GAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPW +I ++ + +S S+G+ E L D L PL +N+L+ + G ++GIS ASGD G G N + P FPA P+ -PNIPLPAIIAYIVQQDEVNVVSQSFGIPE-----LYVDLGLIPL--SYVNSLMYEYWLGEVEGISFAAASGDAGGNGYNYFLA---PQGSVIFPASIPY VTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLI V A GGS++ I N T E W G E + AS GG S L+ P YQ VLAVGGSSVYIGG--------NKTMETAWSG---------------------ESVLGASTGGYSTLFPAPWYQDS------------------------- HGYRSGRNYPDVVANADPITG-YDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVY +G+R PDVVA+A+P TG + +Y N + L+GGTS P + + +M ++G NP LY L T S + + N YYV NGFRV---VPDVVADANPYTGAFILYYYNQTY-LVGGTSLATPIVSGIIDLMTQSYG-KLGFVNPFLYELRNT--SALSPIGFGYNTP--YYVNS--SEL NQAAGLGTVN N GLG++N NPVTGLGSIN
Show aligned area	124382298	Burkholderia mallei NCTC 10229	serine protease	766	1e-18	0.24	0.40
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANGFGDITVSANNKLIFAQGNASNAERGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK-SPAQ--------VKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L + +PA K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGI N D L + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------ SVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP +++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TLSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQ ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S STGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	126456407	Burkholderia pseudomallei 1106a	serine protease, subtilase family protein	766	2e-18	0.24	0.40
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANGFGDITVSANNKLIFAQGNASNAERGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK-SPAQ--------VKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L + +PA K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGI N D L + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------ SVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP +++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TLSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQ ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S STGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	116624687	Solibacter usitatus Ellin6076	peptidase S8 and S53, subtilisin, kexin, sedolisin	1233	2e-18	0.25	0.39
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGL-LIRVKGHVATINKAFAVNLKTARYHGKKIQFS ++LKP K+L+ A S ++ +L+P+QF +FG ++ +++ + + L+A G I G + + +GK + LILKP--AKSLAAFLAAQQIPGSPEYRQFLSPEQFADRFGLTTDDLTKVVGWLESQGLKADRIARGRNAITFSGTAEQAARTLKTEFHRYQVNGKMHFAA KQAPRLPKQVAQPIRAVVGVTNLMI---AKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGR P +P+ + + G+ + + A T + VK P Y+ L +G G GQ + I+ + + I+ F +Q +P AAEPSIPEALGDVVAGFTGLDDFKLESNALRSTLRPQYTVKSGDHYLVPDDLATIYNLKPLYQAGIDGTGQKIAIVGESDIDLSDIRAFRQQFNLPAGTD LETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAK-VRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLA G +N + E LD E AG IA AK V VY+ LDA A EN A LS+S+G E + + +A PVQILVGDDPGFNN---TWFEADLDIEWAGAIARGAKIVYVYSNSV-----LDAVQYAVDENVAPVLSMSYGSCE--------------AFNQVEFRAVA QGAI-QGISTFVASGDTGAY--GQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEEL Q A+ QGI+ VASGD GA + A G A FPA P VTA GG+T N R W G L +I P + QQAVAQGITFLVASGDHGAAECDRYTQTPQASKGFNASFPATLPEVTAVGGTTF------------NEGSGRYWASGNDANG--ASALSYI--PEVAWND TA------ASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAA TA A+GGG S L+G P +Q G +GV AR + PDV +A + S + L+GGTSA P FA + A TASIGDVEATGGGASILFGKPYWQVG-SGVPNDKAR----------------------DIPDVSLSASAEHDPYLISYFGDFYLVGGTSASTPAFAGIVA VMNSDRSQR-------MGLWNPQLYALAQTDHSPFTRL----------DAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSY ++N ++ + +G NP LY AQ F + + N N + G Y+ GLG+V+ KL ++ LLNQNQLSKGTISKPGLGNINPNLYRQAQAGDGSFHDITGGDTMIPCVQGSPNCVNGQMGLRAGTGYDLVTGLGSVDANKLINNW
Show aligned area	126445251	Burkholderia pseudomallei 668	pseudomonalisin	766	2e-18	0.24	0.39
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANGFGDITVSANNKLIFAQGNASNAEHGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK-SPAQ--------VKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L + +PA K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY-----------------GQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGIS N D L + + Q QG V+SGD G Y G ++ ++ PA SP+V A GG+ + -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGAPGYVGTYSGGKVTTKISLAKYSVSSPASSPYVVAVGGT------------T VNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPI ++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A LSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQS TGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S TGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	76819123	Burkholderia pseudomallei 1710b	sedolisin-B	766	3e-18	0.24	0.39
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANGFGDITVSANNKLIFAQGNASNAEHGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK-SPAQ--------VKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L + +PA K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGI N D L + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------ SVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP +++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TLSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQ ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S STGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	53716839	Burkholderia mallei ATCC 23344	serine protease	644	4e-18	0.24	0.39
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANDFGDITVSANNKLIFAQGNASNAERGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLT---------TKSPAQVKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L ++ A K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGI N D L + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------ SVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP +++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TLSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQ ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S STGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	126450809	Burkholderia mallei NCTC 10247	serine protease	633	6e-18	0.25	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTPGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTLTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL I +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSIDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	124384594	Burkholderia mallei NCTC 10229	serine protease	633	6e-18	0.25	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTPGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTLTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL I +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSIDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	121601326	Burkholderia mallei SAVP1	serine protease	633	8e-18	0.25	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTPGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTLTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL I +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSIDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	53723722	Burkholderia mallei ATCC 23344	serine protease	633	8e-18	0.25	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTPGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTLTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL I +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSIDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	126439415	Burkholderia pseudomallei 668	serine protease	633	1e-17	0.24	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T+ S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTSGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTPTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSTDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	53722994	Burkholderia pseudomallei K96243	sedolisin-B	644	1e-17	0.24	0.39
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + A + + +A T + N LI +G+ + F LK Y GK + + IVLKSRNEAQLDSLVREVNQPGSANYRKYLTPEQFKARFAPTDAQVRAVVAHLKANGFGDITVSANNKLIFAQGNASNAEHGFHTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLT---------TKSPAQVKHLTAK-----RSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L ++ A K+ TA PT F + Y+AS L + TVGII++G + A + DSAALVPASLSPVVESVLGLQSAAVPHRLIHRGTPADARIQTDAITKNATASGTQTGHQPTDFAQIYNASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA--------KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILR F R AG+P + G T+ D+GD E LD++ GT ++ Y A ++ A+ A +N A +++S G E TFTRNAGLPNVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTAAYNKAVTDNVAKVINVSLGEDEAA-- DLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGI N D L + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ -ANSDGSLAA-----NDAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------ SVNVTRERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP +++ + TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TLSTSGTTTWAGETVWNEGLAYADVSSSGQPLDNAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQ ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS TG + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S STGAYLVINGQPNQLVGGTSLASPIFVGGWARVESANGNGLGLPTSAFYQGLPGNPSLVHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	120406859	Mycobacterium vanbaalenii PYR-1	kumamolisin	534	1e-17	0.27	0.39
QSSATTSRLTRYFRACHLQATAANNGLLIR---------VKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTK QS T+ LT R L A + L +R V+G + +AF V+++ Y G+ Q +P P V + +RA V +++ QSIEFTASLTDRSRPTALIDWARDRSLSVRWRPGDDWVVVEGSPDAVTQAFDVSVRD--YRGRMGQLFYASPHQPA-VPEHLRAEVSEMGRILSFIPHRM S-PAQVKHLTAKRS--PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTI S P + R P L Y+A +LA +G G G T+ + +F + + F G+P + + GG+ G E ++D + A I SRPDHIPLNVPDRGLGPDALLNAYNADDLARAGFTGKGITIVVFAFDGFRQSDLDTFTTMFGLP---QFTPEIVGGSPGEPRG-----ELSMDLQVAHAI APRAKVRVYTAK--------FSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY----GQ AP A+ V A+ + IG + T S S+ WG D L+T + + L G + + ASGD GQ APDARKVVVNARPTVEDGGGYRKIGEMLEDTDRRFPGAVWSFSIGWGC----------DKLITAADLAPVRSALRTAQSHGTTAYNASGDLAGMECRGGQ NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV + S + I D A P +T+ GG+TL T A G V+ E+TW + P L+ +GGG+S L+ P +Q+ AG DWSSPPSEQDIGLDSIASLPEMTSVGGTTL---STDADGTWVS---EQTW---------YDVP------------LSQGTGGGVSALFDMPAWQRTAAG- NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNS----DRSQRMGLWNPQLYALAQTDHS AV P+ R PDV A ADP TG I + + GGTS AP +A + AVMN +G NP LY +A+ ----------AVPPERNT-------GKRMTPDVAAVADPFTGVKIVLDDQVL-VGGGTSQSAPIWAGLTAVMNQYLLEHNGTLIGDINPLLYRIAEGAPR PFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ P R T GN PG Y+ GLGT + + L R+ Q PAYR--DVTLGGNAVDNAGPG--YDLVTGLGTPDIDNLVRNLQ
Show aligned area	15922696	Sulfolobus tokodaii str. 7	pseudomonapepsin	1301	2e-17	0.30	0.43
DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWL-DAFTTAFAENRASSLSLSWGLSENILRDLNRDHLL--TPL----YGDIMNTLLAQGAIQGISTFVA D ETALD E IAP A + + S G + +A +E+ A+ S+S+G+ EN + D + P+ Y D A G ++GIS F A DIETALDVETVHAIAPYAHIVLVVP--STPGLIPEAIDYIVSEDLANITSMSFGMIENTIGDTGFYFVFDGVPMPNLPYWDYY---FALGTVEGISFFAA SGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTP SGD GAYG L+ + +PA SP+VT GG++L + T + N T T+G F G+ L F P + S GG S Y P SGDEGAYGGTLTTYGGV-----SYPATSPFVTGVGGTSLYVNVTSGYLSAQNST--TTYG---FETGWSIFNLDF---PFI------GSDGGYSTYYPKP KYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA YQ + G R PDV A+A+P TG IY E++GGTS P +A +AA + S + +GL+N LY + WYQYMINGTT--------------------------RATPDVAADANPYTGLLIYVLGQE-EVIGGTSLSTPIWAGLAADIVSIIHKPLGLFNNILYWIY QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLARSYQ T N Y G YN GLGT +F L ++ + SNSTLYNQAFHQITFGFNGLYSAHSG--YNLVTGLGTPDFYGLLKAVE
Show aligned area	76809593	Burkholderia pseudomallei 1710b	serine protease	633	2e-17	0.24	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTPGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTPTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSTDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	53719751	Burkholderia pseudomallei K96243	peptidase	629	3e-17	0.24	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTPGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTPTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSTDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	126454247	Burkholderia pseudomallei 1106a	serine protease	628	3e-17	0.24	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKK VSL++ + R + L L +T S ++ +LTP +F A++ + + + + R A A N LLI G A + AF LK G++ VSLNLNDEARLDRFLRDL----HTPGSAAYGRHLTPAEFAAQYAPTPQQVALVEAHLRRAGFRDIEVAPNRLLISATGTAAAVKTAFNTRLKRFTLEGRR IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAK----------------------RSPTKFLKQYHASNLATSGQQGAGQTVGIIS + ++ A ++P ++ + + AV+G+ N +A++ ++ AK P +F + Y A + T+ Q TVG+I VYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGAVGGAKASLAARASDASAAASGAPVLTGHDPLEFSRIYRAGSTPTASQT----TVGVIM FGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG G + F +AG+ T+T G+ DN S+ D A+ G + + SDI A+ A +N A +++S G AGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYSDNSGLSEWDMDSQAIVGAAGGAVKGLVLYAAPSMLLSDI--TSAYNRAVVDNVAKVINVSLG LSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGISVNVT + E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL +T ++ VCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSTDRT-----TLAYA RERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI E W + G + + L A+GGG SR P +Q+ V G + R PDV +AD +G + GEVAWNEGLQPIGVYDAYGSYDGTRRLW-----ATGGGYSRSEAAPAWQRSVLGASA-----------------------KARALPDVAFDADGRSGAHV YSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALA Y N E GGTS AP F + A + SD R+G LY A YV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYA
Show aligned area	94967481	Acidobacteria bacterium Ellin345	protease	1207	7e-17	0.24	0.39
QTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQAT-AANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRL Q L + A +T S + +L + K+G S T+ + + + + AN+ + G VA + AF + G + Q ++ QNTALEAVIKAEHTPGSAKYHHWLKASEIATKYGVSEPDTTAVRGWLASQGFEVKHVANSRRFVVFSGTVAQVEAAFHTQMHQYELSGNSFIANSQEVQI PKQVAQPIRAVVGVTNL-------MIAKSLTTKSPAQVKHLTAKR--SPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGR P +A +R VV +T+ ++ K+ K Q+ + +P F Y+ + L +G GAGQ++ I++ + + + F GV PAALAPVVRGVVRLTSTPKNNNVKIVGKAAFDKEKGQITFTNGEHAITPADFATIYNLNPLYQAGINGAGQSIAIVARSDIYSRDVFDFMSIFGV----- LETKTTGGATVMDNGDD------SDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENR-ASSLSLSWGLSENILRDLNRDHLLTPLYGDI + GG NGDD SD E LD A IAP A + ++ + +D +N A +S S+ E + P+ + ----SFGGFYYTINGDDPGYVSGSDVEATLDLTWAAAIAPGATPNIVISQSNFADGVDISAAFIVDNNLAPVMSTSFSSCE---------QQMGPVGTEF MNTLLAQGAIQGISTFVASGDTGAYGQNL--SESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFF----KGYHQHPLQFI +L AQ A +GI+ V+S D+G G +L S + A G+ + A +P+ A GG+ T P + T + T + K +++ + YYSLWAQAAAEGITAVVSSDDSGGAGCDLPGSGTFAQNGLAVNALASTPFNVAVGGTQF--DDTADPSKYWSSTNDSTTKASVLSYIPEKAWNESSIDSG KHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI----YSKNSGWELMGGTSAVAP + A GGG+S L+ P++Q G GV P G R+ PDV A GY + ++ G +GGTSA AP NVSLW------AGGGGVSTLWTKPEWQIG-TGV-------------PADGM---------RDLPDVSLTAAGHDGYVLCFGGSCESGGIYTVGGTSASAP QFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATN-----NGNLYYVGQPGKVYNQAAGLGTVNFEKLARSY FAA+ A++N G N +Y LA F N NG G Y+ A GLG+ + L ++ AFAAIMALVNQQTGSPQGNPNYVIYQLAAQHPEFFHDTTVGDNKVPDMNGEFTVGYSTGVGYDLATGLGSFDANSLVTNW
Show aligned area	116624689	Solibacter usitatus Ellin6076	peptidase S8 and S53, subtilisin, kexin, sedolisin	1226	1e-16	0.26	0.39
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGL-LIRVKGHVATINKAFAVNLKTARYHGKKIQFS ++LKP +L+ S + +L +F +FG SSA +++ + ++ L+ G I G A + F + G+ + VLLKP--DSSLNDFLANQQLPGSPDYHRFLNSDEFGQRFGLSSADLAKVVSWLQSEGLKVDEVARGRHWITFSGTAAQAARTFHTEFHRFQVEGRMHFGN KQAPRLPKQVAQPIRAVVGVTNLM--IAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRL P +P + + G+ + +A+ L + H SP F Y+ S L +G G GQ + I ++ ++ F G+P AGEPAIPAALESVVGGFTGLDDFATHVARPLPQTNLIGGAH---GLSPDDFATIYNISPLYAAGIDGTGQKIAIAGEVNLNLTDVRSFRNTFGLPANDP- ETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAK-VRVYTAKFSDIGWLDAFTTA---FAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTL + G ++N ++ E LD E AG +A AK V VY A D FT A +N A LS+S+G E + I DVILVGRDPGVNN--NALLEADLDVEYAGAVARNAKIVYVYAA--------DVFTAARYAIDQNLAPVLSVSFGACE--------------AFSQISYRA LAQGA-IQGISTFVASGDTGAYGQNLSESSAMP----GIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPIL +AQ A QGI+ VASGD GA +S +P G A FPAD P VT+ GG+ N R W + L +I VAQQANAQGITFLVASGDLGA--ATCDHASPVPQASKGAHASFPADLPEVTSVGGTMF------------NEGDSRYWSNNS--TASTASALSYIPEVAW LEELTAAS----GGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWEL--MGGTSAVAPQFA E + +S GGG S+ + P +Q AG + R R+ PDV + G+D Y L +GGTSA AP FA NESASLSSLTSGGGGPSQYFSKPFWQ---AGPGVPDDRF--------------------RDTPDVALAS--ALGHDPYLVMWRGSLVAVGGTSAAAPAFA AMAAVMNSDRSQR-------MGLWNPQLYALAQTDHSPFTRLDAATN------------NGNLYYVGQPGKVYNQAAGLGTVNFEKLARSY + A++N R +G NP LY LAQ+D F + + N NG+L Y PG Y+ A GLG+V+ KL + GIVALLNQSLVGRNLLARPGLGNINPALYRLAQSDKDAFHDITSGDNFVPCVQGSADCVNGSLGYAAGPG--YDMATGLGSVDAAKLVAKW
Show aligned area	15922823	Sulfolobus tokodaii str. 7	pseudomonapepsin	1288	1e-16	0.24	0.38
LVTVA-TPY-RQSRLQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGL L+TVA T Y ++L + + + + V + + + L A AV+ S + +L Q F + + +Y + + LLTVAQTQYIPPTQLNGFHKIGSLPSNEKVIFTVYIPLKNLGLLYYYAYAVSNPSSTLYHHFLNKTQIEKLF-YPTTEYEHVLQYLKENGFNILFTASDS LIRVKGHVATINKAFAVNLKTARYHGKKIQFSK--QAPRLPKQVAQPIRAVVGV---TNLMIAKSLTT--KSPAQVKHLTAKRSPTKFLKQYHASNLATS +I +G VA I VN A Y + + P+LP V + T L+ KSL ++ Q + A PT K Y+ + L + IIVAEGSVAQIENTLGVNY--AVYSNGSLTYYTVYGVPKLPVYVVSNNLTTIFFNHPTTLITQKSLEKFYQTVNQTFSIEA-YWPTALQKVYNLTFLFNN GQQGAGQTVGIISFGHVPTAA--IKHFWRQAGVPTTGRLETKTTG------GATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTT G +G T+GI+ F P A + +F G+P G G G E +LD E A T+AP A + +Y A ++ + GYKGQNYTIGILDFYGDPYIAQQLAYFDEITGLPNPPNFTIVPIGPYNPNLGILTGWAG-----EISLDVEIAHTMAPEANITLYIAN-PNLPLSAVISY AFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTF ++++ LS S+ + E+ N + + + + + A G +GI+ +SGD G G S P +P+ SP+V A GG+T I+ IVSQDKVDVLSQSFSIPESSFSSFNGELFYSCVV--LTDEYYAMGVTEGITFLASSGDAGGSGY-----SNGPIGTVGYPSVSPYVIAVGGTTTYIQ--- APGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVAN P S T +G F Y S GGIS + P YQ ++ TY +GR PDV AN FPNGSYYQTAWSNYGFVPNFINY------------------GGSTGGISIVEPKPWYQSSLSTPVTYP---------------------NGRETPDVSAN ADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLAR AD G I + + GGTS +P A + S ++++GL P LY +A+ T N+ + G YN G GT+NF +LA ADVFPGIYIVCPGNVTAITGGTSEASPLTAGALVTVMSYLNKKLGLITPTLYMIAENSSLYNKVFYPITFGYNIPWTTNYG--YNLVTGWGTINFGELAT SYQ + Q TLQ
Show aligned area	83717441	Burkholderia thailandensis E264	serine protease	669	1e-16	0.24	0.41
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFS IVLK R L L VN S +++ YLTP+QF+A+F + + + +A T + N LI +G+ + + F LK Y GK + + IVLKSRNEAQLDALVREVNQPGSANYRKYLTPEQFKARFAPTDGQVRAVVAHLKANGFGDITVSANNKLIFAQGNASNAERGFRTTLKRFSYRGKAVYAN KQAPRLPKQVAQPIRAVVGVTNLMIAKSLT---TKSPAQVKHLTAKRS-----------PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIK A +P ++ + +V+G+ + + L T + A+++ T ++ PT F + Y AS L + TVGII++G + A + DSAALVPASLSPFVESVLGLQSAAVPHRLIHRGTPAGARIQTDTITKNAAASSSQVGHQPTDFAQIYGASGLPAA----TNTTVGIITWGDMTQTIADLN HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTA---KFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRD F + AG+P+ + G T+ D+GD E LD++ GT ++ Y A +D G +A TA A N+A + ++ ++ ++ D TFTQNAGLPSVNTAVVAGSSG-TLADDGDPG--EWDLDSQTIIGTSGGVKQLIFYAAVNGDSNDSGLTNATLTA-AYNKAVTDDVAKIINVSLGEDEAAS HLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADF------------------PADSPWVTATGGSTLPIKKTFAPGISVNVT + L + + + Q QG V+SGD G Y + S A PG + PA SP+V A GG+ +++ + NSDGSLAAN--DAVFKQAVAQGQIFSVSSGDAGVYQWSTSPYGA-PGYVGTYSGGKVTTKINLAKYSVSSPASSPYVVAVGGT------------TLSTS RERTWGGD-IFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYD TW G+ ++ +G + P+ A+GGG+S P +Q G + + R PDV +A TG GTTTWAGETVWNEGLAYADVSGSGQPLDSAVRLWATGGGVSGYEAAPSWQTAALGSSV-----------------------TKRVVPDVAFDAAQATGAY IYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKLARS + +L+GGTS +P F A + S +GL Y + S + + N N Y Y + G ++ G G+++F K++ S LVINGQANQLVGGTSLASPIFVGGWARVESANGNSLGLPTSAFYQGLPGNPSLIHDVTSGNNGYNSYGYSAKSG--WDDDTGFGSLDFAKVSAS
Show aligned area	83718906	Burkholderia thailandensis E264	serine protease	694	1e-16	0.23	0.39
AKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAAN-NGLLIRVKGHVATINKAFAVNLKTAR A + V + + L L + L ++T S ++ LTP +F A+ + + + + R + + N LLI G A + AF LK APGEPVRVVVSLNLNDEAKLDRFLLDLHTPGSAAYGRPLTPAEFTARHAPTPQQVALVEAHLRRAGFRDIEVSPNRLLISATGTAAAVKTAFNTRLKRFT YHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRS----------------------PTKFLKQYHASNLATSGQQGAGQT G+++ ++ A ++P ++ + + AV+G+ N +A++ ++ AK S P +F + Y A T+ T LEGRRVYANQDAAQVPAELGRIVGAVLGLDNATLARTYNRQAAVTGTVGGAKASLAARASDATAAASGTPVLTGHDPLEFSRIYRAGATPTASLT----T VGIISFGHVPTAA--IKHFWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSL VG+I G + F +AG+ T+T G+ DN S+ D A+ G + + SDI +A+ A A+N A + VGVIMAGDAAPVLRDLDTFAAKAGLARVAATVTRTGPPGSDYNDNSGLSEWDMDSQAIVGAAGGEVKGIVFYAAPSMLLSDI--TEAYNRAVADNVAKVI SLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEA------DFPADSPWVTATGGSTLPIKKTFAPGI ++S G+ E R + + QG + VA+GD GAY ++S S G+ A PA SP+V A GG+TL KT NVSLGVCEADARASGTQA--------ADDRIFKSAVAQGQTFVVAAGDAGAYECSVSRVSGGQGVPARSNYSVSEPATSPYVVAVGGTTLSTDKT----- SVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPI ++ E W + G + + L A+GGG S+ P +Q+ V G + R PDV +AD TLAYAGEVAWNEGLQPIGVYDAYGSYDGTQRLW-----ATGGGYSKNEAVPAWQRSVLGASART-----------------------RALPDVAFDADGR TGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA +G +Y N E GGTS AP F + A + SD R+G LY ++ + R + +NG+ Y + G ++ G G+++ A SGAHVYV-NGRTEQWGGTSLAAPIFTGIWARVQSDNGNRLGFPLASLYRYVPSNRA-LARDVKSGHNGSGGYGYKAGAGWDPVTGFGSLDVANFA
Show aligned area	117928870	Acidothermus cellulolyticus 11B	physarolisin II	658	2e-16	0.26	0.38
MKKMGLIVTSLVVGLICFGGIQGQAAKLVTVATPYR----QSRLQHLYHVKKVAK---KKTVSLDIVLKPRQ-TKTLSQLALAVNTTDSQSFKGYLTPQQ ++++ ++ + +G++ I AA L A+P R SR L H + + + V I L P L+ ALAV+T S + +L+P + VRRLTIVAAASSLGVV----ISSFAAPLAAHASPARSPVPHSRPGWLTHARDLGRAPATAAVQARIYLAPNGGLDALAARALAVSTPGSADYGHFLSPAE FRAKFGQSSATTSRLTRYFRACHLQATAAN-NGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGV--TNLMIAKSLTTK + A+FG + AT +TR+ + L T + + + G VA +AF V++ + G+ +Q P +A + AV G+ T ++ +L YFAEFGTTDATVRAVTRWLTSSGLTVTGVEAHNRYLDITGSVAAAERAFGVHIHAYSHDGQTVQAPDDTLTTPADLADDVLAVDGIDTTPNIVRPAL--- SPAQVKHLTAKRSPTKFLKQ------YHASNLAT-----SGQ------------------------QGAGQTVGIISFGHVPTAAI---KHFWRQAGVP- + V + A P + Y+ LAT +GQ G G TVGI PT A + R P AAGAVPYRGAPIPPPAGFRNAAPCSSYYGEKLATDLPSFNGQALPYAVCGYVGAQFRSAYEGATTLDGTGITVGITDAYASPTIAADAATYAVRNGDRPY TTGRLETKTTGGATVMDNGDDSD--DETALDAEQAGTIAPRAKVRVYTAKFS-DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDI G+L T D S E LD E +A AK+R Y + D LDAF E R +S SWG E +H T L APGQLTQSLPRTFTNTKLCDASGWFGEETLDVEAVHAMAQGAKIRYYASSSCLDRDLLDAFARINDEARVQIVSNSWGAVEQ------SEHRSTIL---A MNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILL QGA++GIS +SGD+G E ++ + D+PA P+VTA GG+ I T + E WG + + L YEQAFLQGAVEGISYVFSSGDSG------DEVASSGTKQTDYPASDPFVTAVGGTATAIDATG------RLAWETGWG--TYRYALAPDGTAWSSSGTFL EELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITG--------------YDIYSKNSGWELMGGTS SGGG S ++ P YQQG+ T G R PDV +AD TG YD Y +GGTS ----YGSGGGESTVFAQPIYQQGI------------TPAG-------------ARGVPDVAMDADVTTGMLVGQTQAFPDGTYYDQYR-------IGGTS AVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQT AP FA M A+ +GL NP +Y A T LAAPLFAGMTALTFQHARGGVGLLNPTIYRNAGT
Show aligned area	94969465	Acidobacteria bacterium Ellin345	peptidase S8 and S53, subtilisin, kexin, sedolisin	1251	3e-16	0.23	0.38
IVLKPRQTKTLSQLALAVNTTDSQS--FKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGL-LIRVKGHVATINKAFAVNLKTARYHGKKIQ ++L P + + AL + DS S F +LTP +F +FG S + + + + L +G I G V+ + K FA + + +GK+ LLLAPTTQQDAAAKALVKDLHDSSSPNFHKWLTPAEFGKRFGVSENDAAAVRTWLESNGLTVHEVADGRRFIVFSGSVSQVEKTFATEMHSYSRNGKEFI FSKQAPRLPKQVAQPIRAVVGV------TNLMIAKSL---TTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQ + ++P +A ++ VV + + + K + T + + +P F K Y+ L +G G GQT+ I+ G++ + +++F ANASEIKIPAALAPVVKGVVRLHSDPPKSQAYMGKKVHWDPTSGQWEGGDGSHYLAPADFAKIYNLDPLYKAGIDGTGQTIAIVGRGNIFLSDVQNFRTL AGVPTTGRLETKTTGGATVMDNGDDSDD------ETALDAEQAGTIAPRAKVR--VYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH +P ++ NGD+ + E LD +G +AP A ++ V + FSD G + N A +S S+GL E FNLPVND---------PEIIVNGDNPGETSGDVPEATLDVTWSGAVAPNAHIKFVVSQSNFSD-GVDVSAAYIVDHNLAPVMSTSFGLCEA--------- LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYG--QNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQH TP+ N L Q A QGI++FV++GD G G + + A G+ A +P+ A GG+ T P T + T G YFTPVQNAFYNALWQQAAAQGITSFVSAGDNGGAGCDEPGGGTYAFNGLNVSGLASTPYNVAVGGTQF--DDTDDPTKYWASTSDPTTGAS--------- PLQFIKHPILLEELTA-------ASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI-----YSKNS L +I + E A GG+S LY P +Q + R PD+ A GY + S ALGYIPEKVWNESSNDPNSPGLWAGSGGVSSLYKQPDWQTVSTSITG-----------------------GMRALPDISLTAAQHDGYLVCLFQNCSYGE GWELMGGTSAVAPQFAAMAAVMNSDR-SQRMGLWNPQLYALAQTD---HSPFTRLDAATNNGNLYYVGQPG-KVYNQAAGLGTVNFEKLARSY + + GGTSA +P A + A++N Q G+ N Y LA T H + + +Y VG Y+ A GLG+ + L ++ YFYVFGGTSASSPAAAGIMALVNQKMGGQPQGMANYVFYKLASTPGVFHDTTVGDNKVPDASGMYTVGYDAVSGYDLATGLGSFDANALVNNW
Show aligned area	186471674	Burkholderia phymatum STM815	peptidase S53 propeptide	534	8e-16	0.25	0.39
KGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG-LLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNL--- + YLT ++ + G S + + + L+ + G + ++G + + AF +++ + + + LP+++++ + V G RKYLTHEELAEQHGASKEDLDMIEHFAQQHDLKVAHRSAGERAVVLQGRLGDLLGAFHADVQMYHHAAGTYRGRRGEISLPQELSKIVTGVFGFDTRPKH ---MIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDET KS P + A T F K+Y+ G GQT+GII G + + F+++ GVPT D D E REPHRQKSAAQNGPGNGNGVAA----TVFAKRYNFP----PQLDGTGQTIGIIELGGGYRRSDLNAFFKEIGVPTPQVSSVSIDHAGNHPSTPDSDDGEV ALDAEQAGTIAPRAKVRVYTA-KFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYG LD E AG +AP+AK VY A D G+LDA + A +E + S +S+SWG E ++ D Y + L A A GI+ ASGD G MLDIEVAGAVAPKAKYVVYFAPNIGDQGFLDAISAAVHDSERKPSVISISWGSPE-----VSTDEQGLKAY----HELFAAAASLGITVCAASGDHGT-- QNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAG NL I + PA V GG+ + R+ W F Q A+GGG+S + P YQ+ AG ANLDAGHWDGKIHVNHPACDDLVLGCGGT------------QITGGRDVVWNDGTPFNVNVQ------------GGGGWATGGGVSAAFPVPAYQKN-AG VNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANA-DPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPF ++ P I +GR PD+ +A + T D S GGTSAVAP AA+ A +N +++ +G NP LYA A F ID----------------PVSIDSGTAGRGVPDIAMSATNYFTRVDTSEGPS-----GGTSAVAPLMAALVAQLNQGKAKNVGFLNPFLYANASK--GIF TRLDAATNN-GNLYYVGQPGKVYNQAAGLGT + + TN N Q ++ GLGT NDVTSGTNAIKNTIKGYQAASGWDACTGLGT
Show aligned area	111222088	Frankia alni ACN14a	peptidase (partial match)	991	1e-15	0.27	0.40
QQFRAKFGQSSATTSRLTRYFRACHLQATAANN--GLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTT +QF A+ G + + L R F A H + +++ G V + +AF V L + G + +P+++A + AV+G+ + RQFAARHGARAQDLAAL-RLFAAEHDLDVVEEHQPARTVKLAGSVGQMGRAFRVRLDRWEHPGGWYRGRTGPVHIPEELAGVV-AVLGLDD--------- KSPAQVKHLTAKRSPTKFLK----QYHASNLATSGQ---QGAGQTVGIISFG---HVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETAL PA H + SP + +++A+ LA G GQTV I+ FG +P A +W G T ++ + + GA D ET L -RPALRTHHRHRPSPGPDARGADSRFYATALAARDHYPATGGGQTVAILEFGGGYSLPDLAT--YWSAIG-HTPPQVSSISVDGAANSPGSDGGSVETML DAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRAS--SLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNL D +AP+A+ VY A + G++DA+ A + S ++SLSWG +E TP + +L A+ GI+ T + G + DIAILSAVAPQARQAVYVAPNTSAGFVDAYLAAIHDTVTSPCAISLSWGSAE---------QNWTPAAISALEDVLHTAALFGITC------TCSSGDDG SESSAMPGI-EADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVN S G+ AD+PA SPW+ A GG+TL +T E W SGGGIS L+ P YQ SSDGVHDGLAHADYPASSPWMLACGGTTLV-------RTGQTITDEVVWD---------------------WGGADGNSGGGISDLFDLPDYQAS----- TYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLY T + P P G R GR PDV A G I W ++GGTSAV+P A +AA + R+G +P LY --------TNIPPSINP----GSRIGRGGPDVATAA--ADGTSIVLVGGQWAVIGGTSAVSPMLAGLAAQLTQTLGYRVGHLHPFLY
Show aligned area	206562777	Burkholderia cenocepacia J2315	serine-carboxyl peptidase	610	2e-15	0.24	0.39
SLDIVL--KPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGK S+DIVL R L Q ++T S ++ +LTP QF A++ + + + + R A + A N LL+ G AT+ AF LK +G+ SVDIVLGLNLRNEAQLDQYLRDLHTPGSPHYRQFLTPAQFAAQYAPTDQQVASVVAHLRKAGFVNIVVAPNRLLVSASGTAATVQSAFRTTLKRFTRNGR KIQFSKQAPRLPKQVAQPIRAVVGVTNL-MIAKSLTTKSPAQVKHLT-------AKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKH + + A ++P + + AV+G+ N+ ++ +K +LT +PT+F Y T+ Q TVGIIS G + + + SVYANTDAAQVPNAIGNIVGAVLGLQNVELMHTGAGSKPQGNTSNLTIPAGASAVPHNPTEFSSIYGGDGTPTASQ----TTVGIISEGDLSQTVSDLNT FWRQAGVPTTGRLETKT-TGGATVMDNGDDSDDETALDAEQ-AGTIAPRAK-VRVYTAKFSDIGWLD-AFTTAFAENRASSLSLSWGLSENILRDLNRDH F G+ T KT G++ D D E LD++ GT K V YTA + + A+ A +N A +++S G+ E+ FAANNGLGTISSSIVKTGPSGSSYTDT--DGTVEWNLDSQSIVGTAGGSVKQVVFYTAPSMTLTAITAAYNKAVTDNVAKVINVSLGVCESSAYSTGSQA LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL +T+ Q QG + V++GD GAY + S + + PA SP+V A GG+TL + S V + +W + --------TDDTIFKQAVAQGQTFSVSAGDHGAY-ECASGTPSRSTYTVSEPATSPYVIAVGGTTLFTNTSTNAYNSEIVWNDPSWQPGTVW-------- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELM--------- ++GGG S+ P +Q +T R PDV +AD TG + + + --------------STGGGYSKYEAAPTWQSSTLTGST------------------------KRALPDVGFDADLRTGAILVVNGQTSDTLWGSGYLNNE GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL GGTS AP F + A + S + +G +Y T+ + + + NNG+ Y + ++ G G+VN KL GGTSLAAPIFTGIWARLQSANNNALGFPASSIYKYFPTNAALLHDVTSG-NNGSGTYGYKAKAGWDATTGFGSVNISKL
Show aligned area	70608075	Sulfolobus acidocaldarius DSM 639	hypothetical protein Saci_2374	1074	2e-14	0.25	0.40
GVTNLMIAKSLTT---KSPAQVKHLTAKR-------SPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKHFWRQAGVPTTGRLETKTTGGA G+ L+I+ ++T + P + +LT ++ +P Y+ S L +G G G +GI+ F P + F + + + L+ G GIPGLVISSNITNTLVEKPMNMINLTQEQLQGYSISTPNDIRTAYNVSYLLDNGITGKGVNIGILVFDGNPYIQQELSTFDQLYNITSPPFLDIVPIGPY TVMDNGDDS-DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSE--NILRDLNRDHLLTPLYGDIMNTLLAQGAIQGI D E +LD E A +IAP A + +Y A S++ + +N+ + LS S+G+ E + +L +L + +Y + G GI NPNDGIQSGWALEASLDVEYAHSIAPSAGIVLYVAN-SNLALPEILANIVQDNQVAVLSQSFGIPEIYFLTGELPLSYLQSIMYEYWL------GEALGI STFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISR + +SGD GA G N S P PA P+V A GG++L FA S N T + W G + + +S GG S TFVASSGDAGATGYNFYLS---PMGSQLVPASIPYVLAVGGTSL-----FA---SYNQTYQTAWSG---------------------QSILGSSTGGYSS LYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQ L+ +P YQ + G+ R PDV A ADP TG + N+ ++GGTS +P + + A+ + R+G NP LFPSPYYQS-------------------------LSGF---RKVPDVAALADPYTGVKVVYVNNETVIVGGTSVASPIVSGILALTVQVKG-RLGFINPL LYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVN +Y ++ T ++ N G Y YN GLG +N IYNISNT--PALGKISFGYNGG---YTANSS--YNLVTGLGYIN
Show aligned area	115358023	Burkholderia ambifaria AMMD	peptidase S8 and S53, subtilisin, kexin, sedolisin	534	2e-14	0.23	0.38
SLDIVL--KPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGK S+DIVL R L Q ++T S +K +LTP QF A++ + + + + R A + A N LL+ G ATI AF LK ++G+ SVDIVLGLNLRNEAQLDQYLRDLHTPGSPHYKQFLTPAQFAAQYAPTDQQVASVVEHLRKAGFVNVVVAPNRLLVSASGTAATIKSAFRTTLKRFTHNGR KIQFSKQAPRLPKQVAQPIRAVVGVTNL-MIAKSLTTKSPAQVKHLT-------AKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKH + + A ++P + + AV+G+ N+ ++ +K +LT +PT+F Y T+ Q TVGIIS G + + + SVYANTDAAQVPNAIGGIVGAVLGLQNVELMHTGAGSKPQGNTSNLTIPAGASAVPHNPTEFSSLYGGDGTPTASQ----TTVGIISEGDLSQTVSDLNT FWRQAGVPTTGRLETKT-TGGATVMDNGDDSD---DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLD-AFTTAFAENRASSLSLSWGLSENILRDLNRD F G+ T T G++ D + D ++ G++ +V Y A + + A+ A ++N A +++S G+ E+ FAANNGLGTISSSVVHTGPSGSSYTDTSGTVEWNLDSQSIVGTAGGSV---KQVLFYVAPSMTLTAITAAYNKAVSDNVAKVINVSLGVCESSAYSTGSQ HLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHP +T+ Q QG + V++GD GAY + S + PA SP+V A GG+TL + S V + +W + A--------TDDTIFKQAVAQGQTFSVSAGDHGAY-ECASGKPSRSTYTVSEPATSPYVIAVGGTTLFTNTSTNAYNSEIVWNDPSWQSGTVW------- LQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELM-------- ++GGG S+ P +Q +T R PDV +AD TG + + + ---------------STGGGYSKYEAAPSWQSSSVTGST------------------------KRALPDVGFDADLRTGAILVVNGQTSDTLWGSGYLNN -GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLY-YVGQPGKVYNQAAGLGTVNFEKL GGTS AP F + A + S + +G +Y ++ + + + N Y Y + G ++ G G+VN KL EGGTSLAAPIFTGIWARLQSANNNALGFPASSIYKYFPSNAAVLHDVTSGNNGSGTYGYNAKAG--WDATTGFGSVNISKL
Show aligned area	170736018	Burkholderia cenocepacia MC0-3	pseudomonalisin	610	3e-14	0.23	0.38
SLDIVL--KPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGK S+DIVL R L Q ++T S ++ +LTP QF A++ + + + + R A + A N LL+ G T+ AF LK +G+ SVDIVLGLNLRNEAQLDQYLRDLHTPGSPHYRQFLTPAQFAAQYAPTDQQVASVVAHLRKAGFVNIVVAPNRLLVSASGTAGTVQSAFRTTLKRFTRNGR KIQFSKQAPRLPKQVAQPIRAVVGVTNL-MIAKSLTTKSPAQVKHLT-------AKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKH + + A ++P + + +V+G+ N+ ++ +K +LT +PT+F Y T+ Q TVGIIS G + + + SVYANTDAAQVPNAIGNVVGSVLGLQNVELVHTGAGSKPQGNTSNLTIPAGASAVPHNPTEFSSIYGGDGTPTASQT----TVGIISEGDLSQTVSDLNT FWRQAGVPTTGRLETKT-TGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVY--TAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH F G+ T KT G++ D D E LD++ G K V+ + A+ A +N A +++S G+ E+ FAANNGLGTISSSIVKTGPAGSSYTDT--DGTVEWNLDSQSIVGAAGGSVKQVVFYVAPSMTLTAITAAYNKAVTDNVAKVINVSLGVCESSANSTGSQA LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL +T+ Q QG + V++GD GAY + S + + PA SP+V A GG+TL + S V + +W + --------TDDTIFKQAVAQGQTFSVSAGDHGAY-ECASGTPSRSTYTVSEPATSPYVIAVGGTTLFTNTSTNAYNSEIVWNDPSWQPGTVW-------- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELM--------- ++GGG S+ P +Q +T R PDV +AD TG + + + --------------STGGGYSKYEAAPTWQSSTLTGST------------------------KRALPDVGFDADLRTGAILVVNGQTSDTLWGSGYLNNE GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL GGTS AP F + A + S + +G +Y T+ + + + NNG+ Y + ++ G G+VN KL GGTSLAAPIFTGIWARLQSANNNALGFPASSIYKYFPTNAALLHDVTSG-NNGSGTYGYKAKAGWDATTGFGSVNISKL
Show aligned area	116691988	Burkholderia cenocepacia HI2424	pseudomonalisin	610	3e-14	0.23	0.38
SLDIVL--KPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGK S+DIVL R L Q ++T S ++ +LTP QF A++ + + + + R A + A N LL+ G T+ AF LK +G+ SVDIVLGLNLRNEAQLDQYLRDLHTPGSPHYRQFLTPAQFAAQYAPTDQQVASVVAHLRKAGFVNIVVAPNRLLVSASGTAGTVQSAFRTTLKRFTRNGR KIQFSKQAPRLPKQVAQPIRAVVGVTNL-MIAKSLTTKSPAQVKHLT-------AKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKH + + A ++P + + +V+G+ N+ ++ +K +LT +PT+F Y T+ Q TVGIIS G + + + SVYANTDAAQVPNAIGNVVGSVLGLQNVELVHTGAGSKPQGNTSNLTIPAGASAVPHNPTEFSSIYGGDGTPTASQT----TVGIISEGDLSQTVSDLNT FWRQAGVPTTGRLETKT-TGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVY--TAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH F G+ T KT G++ D D E LD++ G K V+ + A+ A +N A +++S G+ E+ FAANNGLGTISSSIVKTGPAGSSYTDT--DGTVEWNLDSQSIVGAAGGSVKQVVFYVAPSMTLTAITAAYNKAVTDNVAKVINVSLGVCESSANSTGSQA LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL +T+ Q QG + V++GD GAY + S + + PA SP+V A GG+TL + S V + +W + --------TDDTIFKQAVAQGQTFSVSAGDHGAY-ECASGTPSRSTYTVSEPATSPYVIAVGGTTLFTNTSTNAYNSEIVWNDPSWQPGTVW-------- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELM--------- ++GGG S+ P +Q +T R PDV +AD TG + + + --------------STGGGYSKYEAAPTWQSSTLTGST------------------------KRALPDVGFDADLRTGAILVVNGQTSDTLWGSGYLNNE GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL GGTS AP F + A + S + +G +Y T+ + + + NNG+ Y + ++ G G+VN KL GGTSLAAPIFTGIWARLQSANNNALGFPASSIYKYFPTNAALLHDVTSG-NNGSGTYGYKAKAGWDATTGFGSVNISKL
Show aligned area	107026819	Burkholderia cenocepacia AU 1054	pseudomonalisin	610	3e-14	0.23	0.38
SLDIVL--KPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGK S+DIVL R L Q ++T S ++ +LTP QF A++ + + + + R A + A N LL+ G T+ AF LK +G+ SVDIVLGLNLRNEAQLDQYLRDLHTPGSPHYRQFLTPAQFAAQYAPTDQQVASVVAHLRKAGFVNIVVAPNRLLVSASGTAGTVQSAFRTTLKRFTRNGR KIQFSKQAPRLPKQVAQPIRAVVGVTNL-MIAKSLTTKSPAQVKHLT-------AKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKH + + A ++P + + +V+G+ N+ ++ +K +LT +PT+F Y T+ Q TVGIIS G + + + SVYANTDAAQVPNAIGNVVGSVLGLQNVELVHTGAGSKPQGNTSNLTIPAGASAVPHNPTEFSSIYGGDGTPTASQT----TVGIISEGDLSQTVSDLNT FWRQAGVPTTGRLETKT-TGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVY--TAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDH F G+ T KT G++ D D E LD++ G K V+ + A+ A +N A +++S G+ E+ FAANNGLGTISSSIVKTGPAGSSYTDT--DGTVEWNLDSQSIVGAAGGSVKQVVFYVAPSMTLTAITAAYNKAVTDNVAKVINVSLGVCESSANSTGSQA LLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPL +T+ Q QG + V++GD GAY + S + + PA SP+V A GG+TL + S V + +W + --------TDDTIFKQAVAQGQTFSVSAGDHGAY-ECASGTPSRSTYTVSEPATSPYVIAVGGTTLFTNTSTNAYNSEIVWNDPSWQPGTVW-------- QFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELM--------- ++GGG S+ P +Q +T R PDV +AD TG + + + --------------STGGGYSKYEAAPTWQSSTLTGST------------------------KRALPDVGFDADLRTGAILVVNGQTSDTLWGSGYLNNE GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL GGTS AP F + A + S + +G +Y T+ + + + NNG+ Y + ++ G G+VN KL GGTSLAAPIFTGIWARLQSANNNALGFPASSIYKYFPTNAALLHDVTSG-NNGSGTYGYKAKAGWDATTGFGSVNISKL
Show aligned area	48477281	Picrophilus torridus DSM 9790	membrane associated serine protease	1282	7e-14	0.23	0.41
KFLKQ-YHASNLATSGQQGAGQTVGIISFGHVP--TAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS-DDETALDAEQAGTIAPRAKVRVYTAKFS K+L+Q Y+A+ + + G G+GQ++GI+ F P + +F + + + G + + E +LD E + T+AP A + +Y A KYLEQVYNATGMYSMGYNGSGQSIGILDFYGDPFIKEELAYFDHEFNISAPPSFKIVPIGPYYPYEGIETGWAGEISLDVESSHTMAPGANITLYIAN-G DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATG + A + +++R LS S+ + ++ + L + N + A G+ +GI+ +SGD GA G ++ ++ +P+ SP+V A G NCPLSAAISYINSQDRVDDLSQSFSIPDSC-PAIQTSALGYYQCEVVTNIMYAMGSAEGITFSASSGDAGASGYSIGALGSV-----GYPSTSPYVAAVG GSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRS G++ + IS N T +G F+ I S GG+S L P YQ + G + GY GTSTYLDFQGEKLISFNQTAWSNYG--------------FVPPEINY----GGSTGGVSILQPRPYYQDNITGPS---------------------GYPY GRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDH-SPFTRLDAATNNGNLYYVGQPGKVYNQAAG G+ PD+ A G+ + + GGTS +P A + +++ ++G+ +P LY L + D+ + F +D N + G YN G GKMIPDLSFEATVFPGFLYVMPGNETCITGGTSEASPILAGLMTLVDEYNHGKIGMLDPSLYYLGEHDYKNVFIPVDYGYNIPFTAHYG-----YNLVTG LGTVNFEKLARSYQ G++N A +Y+ WGSLNIANFAMAYK
Show aligned area	15922494	Sulfolobus tokodaii str. 7	hypothetical protein ST2167	1082	1e-13	0.25	0.38
LIRVKGHVATINKAFAVNLKTARYHGKKIQF--SKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKR-----SPTKFLKQYHASNLATS +I + I K F T GKKI + S+ + P +V TNL SL P + ++T +P + K Y+ + L VISFQAKAGVIEKLFNGEFVTTTILGKKIYYFVSEGSSSFP--------GIVLATNLT---SLFLSKPNNLVNITQAVAYNMVTPIEIQKAYNITYLLNR GQQGAGQTVGIISFGHVP--TAAIKHFWRQAGVPTTGRLETKTTGGATVMDN-GDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAEN G G+G +GI+ F P ++ F G+P + G D E +LD E A AP A + +Y A + I A ++ GINGSGVNIGILDFEGDPYIYQQLQDFDSIYGLPNPPLFKIVPIGPYNPNDGIASGWALEISLDVEYAHAAAPDAGIILYVANPA-ISIPQAIAYIDQQD RASSLSLSWGLSE--NILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPG S +S SWG+ E +L L +L +Y + G +GI+ ASGD G G N S P P+ P+V + GGSTL EVSVVSQSWGIPEIYFLLGLLPMSYLQAMIYEYWL------GEAEGITFIAASGDAGGNGYNFFLS---PLGSTIVPSSIPYVLSVGGSTLY-------- ISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADP IS N + + W G+ F ++ GG S ++ +P YQ G + R PD+VA+A+P ISGNESYQTAWSGESIF---------------------GSTTGGYSAIFPSPPYQ----------------------------GLKGYRITPDIVADANP ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQT +G I + L+GGTS P A + A + + R+G NP +YAL T YSGVPIVYYYNTTYLVGGTSLATPIVAGIIA-LATQVHGRLGFINPLIYALNGT
Show aligned area	172062824	Burkholderia ambifaria MC40-6	pseudomonalisin	611	1e-13	0.23	0.38
SLDIVL--KPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFR-ACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGK S+DIVL R L Q ++T S +K +LTP QF A++ + + + R A + A N LL+ G ATI AF LK ++G+ SVDIVLGLNLRNEAQLDQYLRDLHTPGSPHYKQFLTPAQFAAQYAPTDQQVASAVAHLRKAGFVNIVVAPNRLLVSASGTAATIKSAFRTTLKRFTHNGR KIQFSKQAPRLPKQVAQPIRAVVGVTNL-MIAKSLTTKSPAQVKHLT-------AKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKH + + A ++P + + AV+G+ N+ ++ +K +LT +PT+F Y T+ Q TVGIIS G + + + SVYANTDAAQVPNAIGGIVGAVLGLQNVELMHTGAGSKPQGNTSNLTIPAGASAVPHNPTEFSSLYGGDGTPTASQ----TTVGIISEGDLSQTVSDLNT FWRQAGVPT--TGRLETKTTGGATVMDNGD---DSDDETALDAEQAGT------IAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENIL F G+ T + + T +G + +G + D ++ + A +AP + TA A+ A ++N A +++S G+ E+ FAANNGLGTISSSVVHTGPSGSSYTDTSGTVEWNLDSQSIVGAAGGSVKQVVFYVAPSMTLTAITA---------AYNKAVSDNVAKVINVSLGVCESSA RDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFK +T+ Q QG + V++GD GAY + S + PA SP+V A GG+TL F + E W YSTGSQA--------TDDTIFKQAVAQGQTFSVSAGDHGAY-ECASGKPSRSTYTVSEPATSPYVIAVGGTTL-----FTNTSTNAYNSEIVW------- GYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELM-- P + ++GGG S+ P +Q +T R PD+ +AD TG + + + ----------NDPSWQQGTVWSTGGGYSKYEAAPSWQSSSLTGST------------------------KRALPDIGFDADLRTGAILVVNGQTSDTLWG -------GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL GGTS AP F + A + S + +G +Y ++ + + + NNG+ Y ++ G G+VN KL SGYLNNEGGTSLAAPIFTGIWARLQSANNNALGFPASSIYKYFPSNAALLHDVTSG-NNGSGSYGYNAKAGWDATTGFGSVNISKL
Show aligned area	48477259	Picrophilus torridus DSM 9790	membrane associated serine protease	1076	2e-13	0.25	0.39
PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFS P++ Y+ + + G G T+ I+ P+ + F G+P G TV ETALD E A IAP A +++ + S PSQIRYAYNINPVYNESIYGNGTTIVIVDAYGDPSINYDVSAFDNLTGLPAVNLTVLYPEG--TVYQENSGWATETALDVEWAHAIAPGASIKLVVSPGS DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATG +DA + + + +SLSWG E+ ++ L I+N + A+ I+ ASGD G+Y + +FPA P+V G GTSLIDAVAYSIYHHLGNIISLSWGEPES---EMGNSEL------KILNNIYKDAALNNITVVAASGDNGSY-------DTTSHLAVNFPASDPYVLGVG GSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRS G L F G V E WGG + ++ SGGG S + P YQ NT+ ++ V +S P LI GVNL----YFKNGEPV----ETAWGG-------------------IANGVSFGSGGGYSSYFKRPYYQDPEDYNNTHRGVPDVSMVAGRSTPVLI----- GRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTD--HSPFTRLDAATNNGNLYYVGQPGKVYNQAA +V N E +GGTS P +A + A+M+ ++ MG NP LY ++ T + FT++ + TN +Y G +N ------IV--------------NGNAEAVGGTSVATPIWAGIIALMDQYMNRSMGFINPVLYQISNTKLYTNAFTQITSGTNG---FYNAHAG--WNPVT GLGT GLGT GLGT
Show aligned area	188577537	Xanthomonas oryzae pv. oryzae PXO99A	peptidase	523	2e-13	0.25	0.40
LTPQQFRAKFGQSSATTSRLTRYFRACHL--QATAANNGLLIRVKGHVATINKAFAVNLK-----TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNL LT F +F S+A + + + L + + A++G +I ++G V AF V L+ T+RY G+ S LP+ + + AV+G+ LTRAAFSERFAASAADLQAVADFAASYGLAVEHSHADSGNVI-LEGTVQQCEAAFHVCLREYVHGTSRYRGRTGPVS-----LPQALTGIVTAVLGLDAR MIAKSLTTKSPAQVKHLTAKRSPTKF------LKQYHASNLAT----SGQQGAGQTVGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNG A++L + A TA P + QY LA G GQ +GII G + ++ Q +P ++ G + +G PQAQTLPSVPDASASLPTATPPPAPASPEDGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYAREQMAAYFAQLRIPMPTLVDVLLPGATNTVSHG D-DSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVAS ++D E +D + AG + P AK+ VY A +D G+L+A A E+ + +SWG +E+ TP + A+ GI+ +A+ TANADVEAQMDIQIAGALVPGAKLVVYFAPNTDNGFLEAINAAIHDTEHAPGIIVISWGFTES---------QWTPQSRQAYDCAFQAAALMGITVCIAA GDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPK GD GA PG+ FPA SP+V A GG+ L ++ + E+ W A GGG SR + P GDDGA-------GDGQPGLNVCFPASSPFVLACGGTRLQ--------VTADSANEQAW---------------------------ANGGGGESRFFARPA YQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTS +Q+ + + + L R PDV ANAD TGY + S N +MGGTS WQKDLRLTDAQQQSRQLRM----------------RGVPDVAANADAQTGYYL-SINGQPAVMGGTS
Show aligned area	15897997	Sulfolobus solfataricus P2	protease related protein	1269	3e-13	0.23	0.39
LQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKA L+ + + + V + I + + L A + S + +L+P + + F + +++ Y ++ Q + +I +KG V + K LKEFREIGTLNANEEVIVTIFVPLKNLDLLYYYASGASNPASPLYHKFLSPHEVQQLF-LPTEEYNQILNYVKSSGFQVIFTASNSVIVIKGTVGQVEKY FAVNLKTARYHGKKIQFSKQA--PRLPKQV-AQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRS---PTKFLKQYHASNLATSGQQGAGQTVGIISFG K A Y + + P++ V + I A+ + T KS Q + T PT K Y+ + +G T+GI+ F LGT--KYAVYSNGSVTYYTNYGYPKINAYVYSSNISAIFFAHPSTLITESTIKSFQQEINQTFPLEGYWPTVLQKVYNVTT------EGENTTIGILDFY HVP--TAAIKHFWRQAGVPTTGRLETKTTG------GATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWG P + +F + G+P G G G E +LD E A IAP+A + +Y A +I ++N+ +LS S+ GDPYIVQQLAYFDKITGLPNPPNFSVVPIGPYNPNLGIVTGWAG-----EISLDVEVAHAIAPKANITLYIAN-PNIPLPAIIAYITSQNKVDTLSQSFS LSENILRDLNRDHLLTPLYGDIM--NTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERT + E++ L L Y I+ + A G+ +GI+ +SGD G G S P +P+ SP+VT+ GG+T+ ++ P S T IPESLFSSLFNGPL---FYSCIILSDEYYALGSAEGITFLASSGDAGGSGY-----SNGPIGTVGYPSTSPFVTSVGGTTVYVQ---FPNGSYYQTAWSN WGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKN +G F+ + + S GG+S + P YQ G+ +TY +G+ P++ ANA+ G I + YG--------------FVPNNVNY----GGSTGGVSIIEPKPWYQWGLPTPSTYP---------------------NGKLIPEISANANVYPGIYIVLPS SGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVN---FEKL + + GGTS +P A + A + S R+GL NP L +A+ + ++ T N+ +V G YN G GT+N FEK+ NTTGITGGTSEASPLTAGVLATIESYTHHRIGLLNPILTYMAENYYGKV--IEPITFGYNIPWVATYG--YNLVTGYGTINAGYFEKI
Show aligned area	122879242	Xanthomonas oryzae pv. oryzae KACC10331	peptidase	523	5e-13	0.25	0.40
LTPQQFRAKFGQSSATTSRLTRYFRACHL--QATAANNGLLIRVKGHVATINKAFAVNLK-----TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNL LT F +F S+A + + + L + + A++G +I ++G V AF V L+ T+RY G+ S +P+ + + AV+G+ LTRAAFSERFAASAADLQAVADFAASYGLAVEHSHADSGNVI-LEGTVQQCEAAFHVCLREYVHGTSRYRGRTGPVS-----IPQALTGIVTAVLGLDAR MIAKSLTTKSPAQVKHLTAKRSPTKF------LKQYHASNLAT----SGQQGAGQTVGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNG A++L + A TA PT + QY LA G GQ +GII G + ++ Q +P ++ G + +G PQAQTLPSVPDASASLPTATPPPTPASPEDGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYAREQMAAYFAQLRIPMPTLVDVLLPGATNTVSHG D-DSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVAS ++D E +D + AG + P AK+ VY A +D G+L+A A E+ + +SWG +E+ TP + A+ GI+ +A+ TANADVEAQMDIQIAGALVPGAKLVVYFAPNTDNGFLEAINAAIHDTEHAPGIIVISWGFTES---------QWTPQSRQAYDCAFQAAALMGITVCIAA GDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPK GD GA PG+ FPA SP+V A GG+ L ++ + E+ W A GGG SR + P GDDGA-------GDGQPGLNVCFPASSPFVLACGGTRLQ--------VTADSANEQAW---------------------------ANGGGGESRFFARPA YQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTS +Q+ + + + L R PDV ANAD TGY + S N +MGGTS WQKDLRLTDAQQQSRQLRM----------------RGVPDVAANADAQTGYYL-SINGQPAVMGGTS
Show aligned area	84624627	Xanthomonas oryzae pv. oryzae MAFF 311018	peptidase	523	5e-13	0.25	0.39
LTPQQFRAKFGQSSATTSRLTRYFRACHL--QATAANNGLLIRVKGHVATINKAFAVNLK-----TARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNL LT F +F S+A + + + L + + A++G +I ++G V AF V L+ T+RY G+ S +P+ + + AV+G+ LTRAAFSERFAASAADLQAVADFAASYGLAVEHSHADSGNVI-LEGTVQQCEAAFHVCLREYVHGTSRYRGRTGPVS-----IPQALTGIVTAVLGLDAR MIAKSLTTKSPAQVKHLTAKRSPTKF------LKQYHASNLAT----SGQQGAGQTVGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNG A++L + A TA PT + QY LA G GQ +GII G + ++ Q +P ++ G + +G PQAQTLPSVPDASASLPTATPPPTPASPEDGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYAREQMAAYFAQLRIPMPTLVDVLLPGATNTVSHG D-DSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAF--AENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVAS ++D E +D + AG + P AK+ VY A +D G+L+A A E+ + +SWG +E+ TP + A+ GI+ +A+ TANADVEAQMDIQIAGALVPGAKLVVYFAPNTDNGFLEAINAAIHNTEHAPGIIVISWGFTES---------QWTPQSRQAYDCAFQAAALMGITVCIAA GDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPK + PG+ FPA SP+V A GG+ L ++ + E+ W A GGG SR + P -------GDDGAGDGQPGLNVCFPASSPFVLACGGTRLQ--------VTADSANEQAW---------------------------ANGGGGESRFFARPA YQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTS +Q+ + + + L R PDV ANAD TGY + S N +MGGTS WQKDLRLTDAQQQSRQLRM----------------RGVPDVAANADAQTGYYL-SINGQPAVMGGTS
Show aligned area	15899285	Sulfolobus solfataricus P2	serine protease	1308	5e-13	0.30	0.45
DETALDAEQAGTIAPRAKVRVYTAKFSDI-GWLDAFTTAFAENRASSLSLSWGLSENILRDLNR-----DHLLTPLYGDIMNTLLAQGAIQGISTFVASG +E ALD E A AP + + + A + + G A +E+ A +S+SWGL IL + + ++ P Y + G+ +GI+ +SG EEVALDVEAAHAAAPYSNILLVVAPSATLEGLFSAIDVVVSEDLAQVVSMSWGLP-GILFGASGFYAVFNGIIFPNY-PYYDYYFELGSAEGITFLASSG DTGAYGQNLSESSAMPGI--EADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTP D GAY +P + A++PA SP+VTA GG++L T + N T +G +I + +PL F + + +SGGG S+L+ P DLGAYND-------LPTVYGSANYPASSPFVTAVGGTSLFANITSGYISTYNSTG--NFGAEI---AWSVNPLYF-----GVIQGGVSSGGGYSQLFPAP KYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWEL-MGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYAL YQ+ V N YR+ PDV A+A+P TG+ IY+ G E+ +GGTS AP +A + A ++ +GL NP LY + WYQRYVTHSN----------------------YRA---IPDVAADANPYTGFTIYA--LGQEVVIGGTSLSAPLWAGIIADIDGIIGHPLGLVNPILYEI AQTD---HSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVN Q H F ++ N YY YN GLG+ N YQNTTLYHQAFHQISLGYNG---YYYANSS--YNLVTGLGSPN
Show aligned area	94970168	Acidobacteria bacterium Ellin345	physarolisin II	672	7e-13	0.28	0.40
YHASNLATSGQQGAGQTVGIISFGHVPT--AAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDS-DDETALDAEQAGTIAPRAKVRVYTA---KFSDIG Y+ + +G G G+T+ II PT A F G+P + G G+ S ET LD E A IAP AK+ + A F D+ YNLWPMYNAGLDGTGETIVIIDAFGSPTIQADANTFSAINGLPALNSTNFQVVGANA---GGNASWAGETTLDVEWAHAIAPNAKIVLEVAPTNSFVDLF WLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGST + A A A +R +S SWG E D L + IM ++ G ST G YG N+S + + +P SP+ TA GG++ Y--AEVDAIANHRGIVISNSWGGFETF-----TDSSLRGAFDFIMMEAISVGIDVNFST-------GDYGDNVS---VLGYADVQYPGSSPFATAVGGTS LPIKKTFAPGISVNVTRERTWGGDI--FFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSG L + T + + WG +I G P P L+E +GGG S +Y P +Q G T R+ L LALTNTKTKTMKF----QTGWGNNITRLVDGTTGAP----DDPPLMEGFIFGAGGGNSNVYTKPSWQVG-----TNQPRRAL------------------ RNYPDVVANADPITGYDIYSKNSG---WELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWN--PQLYALAQTDHSPFTRLDAATN PD+ ADP TG +I SG E++GGTS AP F+ + A+ N + +GL + QLY++ + A N ---PDIAWLADPYTGVEIIQTISGSQYIEVIGGTSLAAPMFSGIWAIANQKANTTIGLGDAASQLYSMPSGSIKDVVPFNTANN
Show aligned area	29832492	Streptomyces avermitilis MA-4680	serine protease	633	7e-13	0.25	0.37
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKI VS + L + L+ A AV+ +S S+ YL+ QQ +A+FG + A + +T + ++ L+ T + + V G VA KAF L GK VSARVYLAGKDAAGLAAYAKAVSDPNSASYGKYLSAQQAQARFGATKAQVAEVTDWLKSAGLKVTGSTQHY-VTVTGDVAAAEKAFGTQLHNYVKGGKTY QFSKQAPRLPKQVAQPIRAVVGVTNL--MIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHV------PTAAIKHFWRQ + + P + + V G+ N + T P V H + S Y+ S +ATS + G+ + G+ A K + RAPAKTASAPAALDGAVLTVTGLDNAPHKATHADTLPPPDAVFHNSGPYS------SYYGSKVATSLPKAYGKKIPYAVKGYTGKQLRAAYGAGKATGKG AGVPTTGRLETKTTGGATVMDNGDDSD----------------------------DETALDAEQAGTIAPRAK-VRVYTAKFSDIGWLDAFTTAFAENRA V T + T G D E LD E +AP+A V V A D LD+ + A VTVAITDAYASPTIASDAATYAGKHGDAKYAKGQLAQVLPSDYTKTEECGAAGWYGEETLDVEAVHAVAPKANIVYVGAASCYDSDLLDSLNKIVDGHLA SSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVN +S SWG D+ + TP + GAI+GI + +SGD G E + + D PA+S WVTA GG++L + K DIVSNSWG-------DIEANE--TPDVAAAYDQTFKLGAIEGIGFYFSSGDNG------DEVANTGTKQVDTPANSAWVTAVGGTSLAVGK------GDK VTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGY E WG + P ++ +GGG S+ P YQ+GV PKS K +G R PD+ A ADP TG+ YQWETGWG--TLKASLSADGKSWTSFP---GAYSSGAGGGTSKTVAQPFYQRGVV---------------PKSLAK-ANGSTPMRTVPDISAIADPNTGF DIYSKNSGWE--------LMGGTSAVAPQFAAMAAVMNSDRSQR-MGLWNPQLY + + + +GGTS AP A + A+ R R +G NP +Y KVGQTQTFPDGTQKYDEYRIGGTSLAAPVIAGVQALAQEQRGGRAIGFANPAIY
Show aligned area	50954460	Leifsonia xyli subsp. xyli str. CTCB07	peptidase	583	7e-13	0.27	0.38
KQYHASNLATSGQQGAGQTVGIISFGHVPTAA--IKHFWRQAGVP--TTGRLETKTTGGATVMDNGDDSD--DETALDAEQAGTIAPRAKVRVYTAKFSD KQ A G +GAG V I++ P A + RQ G P T + V G S +E LD + +AP AK+ + A KQLRAVQQVPDGYRGAGTKVAIVAAFDDPAVAANTDTYSRQMGEPVLTDDQYAHHAPAHPAVSRCGGPSSWTEEQHLDVQAVHAMAPDAKIEYWGADDCT IGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGG + +SLS+G EN+ D D L +N +L A + IS F +SG+ G Y ++ G PA SP++TA GG TAPMFLRILDAVNAGPDVISLSFGSPENL--DTADDRTL-------LNRVLVDAASRNISVFASSGNDGDYS---AQGDHNTGTSVSSPASSPYLTAVGG STLPIKK--TFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYR ++ I K T A + G + G+ SGGG S +Y P +Q+ TA+ SG TSTGIAKDGTIAVEAGWEIQSRFARNGGLIPPGF-----------------AFGSGGGESTVYDRPSWQR--------------TALASHSG-------- SGRNYPDVVANADPITGYDIYSKNSGWELM---GGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVY +GR DV + ADP TG+ +Y + G GG S P A+M A+ + ++GL +P LYALA T P R + GQ G +Y AGRLVRDVASLADPNTGFVVYGPHDGTTAAVSHGGDSLATPMVASMVALAKATTGVKIGLASPALYALAGT---PALRDVTPASAATWSPKGQKGAIY
Show aligned area	146303633	Metallosphaera sedula DSM 5348	peptidase S8 and S53, subtilisin, kexin, sedolisin	1267	1e-12	0.24	0.39
IVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSK I + R L A V+ S + +L+P Q + F SA S + Y + H+ +I V+G + +++ ++ + IYIPLRNLNLLYYYAEQVSNPGSPLYHKFLSPSQVKNLF-YPSAEFSSVMNYLASHHVHVMFTAADSVIVVQGTASQLSQVLGIHYVLMSNGTTYYYTAM QAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKS-------PAQVKHLTAKRSPTKFLKQ---YHASNLATSGQQGAGQTVGIISFGHVP--TAAIKHFWRQ P++P V I + V +L T+S +LTA K + Y+ S+L + G G TVGI+ F P + +F + GTPKVPGIV---ISSNVSALFFSHPSTLFTQSDVNKLRETVNQPNLTAPIEAYKLTELRGVYNVSSLISKGVNGTNYTVGILDFYGDPYIQQQLAYFDKI AGVPTTGRLETKTTG------GATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLL VP G G T G E +LD E A +AP A + +Y A ++ ++++ +LS S+ + + + + + YNVPAPPNFSIIPIGPYDPNLGITQGWAG-----EISLDVESAHAMAPGANIVLYIAN-GNLPLSSVIAEIVSQDKVDTLSQSFSIPDEFIPEFSGSLFY TPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQF + + + A G +GI TF+AS + S SA P +PA SP+VTA GG+T I TF G S NVT +G F QCVV--LTDQYYAMGNAEGI-TFLAS----SGDGGGSGYSAGPLGSVGYPASSPFVTAMGGTTTYI--TFG-GFSFNVTAWSNYG--------------F IKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFA + + S GGIS++ P YQ G+ + PK G+ +G+ PD+ ANAD G I + + GGTS +P A VPPGVNY----GGSTGGISQVEPKPYYQWGL------------------TTPK---GFPNGKEIPDISANADVYPGIYIVCPGNVTAISGGTSEASPLTA AMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLA + ++ ++G NP LY LA+ D+ T N+ +V G YN G G +N + A GLLTLVMQYTHSKLGNINPDLYYLAKADYQ--KAFYPITFGYNIPWVASYG--YNLVTGWGQLNVGEFA
Show aligned area	78063046	Burkholderia sp. 383	pseudomonalisin	610	2e-12	0.22	0.38
SLDIVL--KPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRA-CHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGK S+DIVL R L Q ++T S ++ +LTP QF A++ + + + + R + A N LL+ G ATI AF LK +G+ SVDIVLGLNLRNEAQLDQYLHDLHTPGSPHYRQFLTPAQFAAQYAPTDQQVASVVAHLRKEGFVNIVVAPNRLLVSASGTAATIKSAFRTTLKRFTRNGR KIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSP-AQVKHLT-------AKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFW + + A ++P + + +V+G+ N+ + + P +LT +PT+F Y T+ Q TVGIIS G + + + SVYANTDAAQVPNAIGGVVGSVLGLQNVELMHTGAGSQPQGNTSNLTIPAGASAVPHNPTEFSSIYGGDGTPTASQ----TTVGIISEGDL-SQTVSDLN RQAGVPTTGRLETK--TTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVY--TAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHL A + G + + TG + D E LD++ G K V+ + A+ A +N A +++S G+ E+ TFAANNSLGAISSSIVKTGPSGSSYTDTDGTVEWNLDSQSIVGAAGGSVKQVVFYVAPSMTLTAITAAYNKAVTDNVAKVINVSLGVCESSANSTGSQA- LTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQ +T+ Q QG + V++GD GAY + S + + PA SP+V A GG+TL + S V + +W + -------TDDTIFKQAVAQGQTFSVSAGDHGAY-ECASGTPSRSTYTVSEPATSPYVIAVGGTTLFTNTSTNAYNSEIVWNDPSWQPGTVW--------- FIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELM---------G ++GGG S+ P +Q +T R PDV +AD TG + + + G -------------STGGGYSKYEAAPSWQSSSLTGST------------------------KRALPDVGFDADLRTGAILVVNGQTSDTLWGSGYLNNEG GTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL GTS AP F + A + S + +G +Y ++ + + + NNG+ Y + ++ G G+VN KL GTSLAAPIFTGIWARLQSANNNALGFPASSIYKYFPSNAALLHDVTSG-NNGSGTYGYKAKAGWDATTGFGSVNISKL
Show aligned area	15898872	Sulfolobus solfataricus P2	peptidase, putative	606	4e-12	0.24	0.38
TVATPYRQSRLQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYL--------------TPQQFRAKFGQSSATTSRLTRYFRACH T T QS+ Q+ Y + + + ++P + +A+ +N T+ S + YL TP QFR + S + + L +Y + + TFLTIIAQSQAQYYYIQTSSPQYTIIPGSVFVEPLNSSQTLYIAVLLNFTNLASLQSYLNEIYLSAPQFHHWLTPSQFREYYYPSRSYVNSLIKYLESYN LQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQF----------------SKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTA LQ N GL++ G V I KAF + Y K + + + P LP + + + VVG+ +L Q HL LQFL-GNYGLILVFSGTVGNIEKAFNTYINVYYYPFKNLYWFGLLGIKNIGPFYYYSNNVTPSLPFNIGKYVLGVVGIDSL---DPKVVNVVTQTWHLPM KRSPTKF----------LKQYHASNLA-TSGQQGAGQTVGI--ISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTI ++ + ++QY LA G G G + I + V + I FW+ G+P TG L G T G ++E LDAE +G VKAQSGLVSKAIISPITIEQYFNFTLAYERGYTGGGSNIAIEGVPESFVNVSDIYSFWQLYGIPRTGHLNVIYFGNVTT--GGQSGENE--LDAEWSGAF APRAKVRV-----YTAKFSDIGWLDAFTTAFAEN----RASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLS AP A V + Y +G L + + + +S+S + E+ L P D+++ ++ Q A QGIS ASGD G Y + APAANVTIVFSNGYVGGPQLVGNLLNYYYEYYYMVNYLNPNVISISVTVPESFLA------AYYPAMLDMIHNIMLQAAAQGISVLAASGDWG-YESDHP ESSAMPGIEAD--FPADSPWVTATGG + G +P P+VT+ GG PPNFHIGTYNTIWYPESDPYVTSVGG
Show aligned area	159042150	Caldivirga maquilingensis IC-167	peptidase S53 propeptide	1317	1e-11	0.26	0.41
PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKHFWRQAGVPTTGRLETKTTGGATV-MDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKF PT Y+A+ L G G T+GII F P + F + G+P G + + E +LD E A IAP A + +Y A PTMLQGAYNATALYEMGYYGQNYTIGIIDFFGDPYIVNQLTQFDYETGLPNPPSFNIIPIGPYNPNLGVYNGWAYEISLDVEAAHAIAPEAGITLYVANP S-DIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTA + + + A+ ++ + +S S+G E+IL +N ++ + + A G+++GI TF A+ + + S P +P+ SP+VTA ALPLAAIIAYIVD--QDNVNVVSQSFGFPESILSTVNGPVFYFNVF--LTDEYYALGSVEGI-TFTAA----SGDGGGAGYSNGPIGAVIYPSTSPYVTA TGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGY GG+T I+ P S T ++G FI L+E S GG+S + P YQ G+ N+Y VGGTTTYIQ---LPNGSYYQTAWSSYG--------------FIP----LDENLGGSTGGVSAVEPKPWYQWGITTPNSYPL------------------- RSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAA GR PDV +A P G I + + GGTSA AP A + ++ +GL NP LY++A + + T N+ + G YN --GRMVPDVAMDASPYPGLLIVGPGNTLLITGGTSAAAPLLAGLLTLIMDYVHSSLGLINPALYSIANNTNEYGKAIVPITFGYNIPWTAHYG--YNMVT GLGTVN GLGT+N GLGTIN
Show aligned area	16082015	Thermoplasma acidophilum DSM 1728	xanthomonapepsin related protein	1090	2e-11	0.25	0.42
SPTKFLKQYHASNLATSGQQGAGQTVGII-SFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKF SP + + Y + G G G+T+GI+ +FG I F + +G+P + T + +ET+LD E A AP A++ + + SPAQVYQAYDYQPAFSRGINGMGETIGIVDAFGDPYLNYDIYAFDQLSGLPPVNL--SVIYLNFTGFNLNSHWIEETSLDVEWAHASAPYARIVLVISNN SDIGWL-DAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTA + L A + R + +SLSWG++E+ L + L+ M+++ + + +GI+ ASGD GAY + +FPA SP+V + DTVSALTSALNYMINDVRPNVISLSWGIAED---QLPKTDLIA------MDSIYEEASQEGITIVAASGDNGAY-------DGTGNLTVNFPASSPYVLS TGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVG-PKSGPKLIHG GG +L FA S E WGG + + + SGGG S ++ P +Q + + ++ + P +G +I G VGGVSL-----FA---SNGRFSESAWGG-------------------ISDGKSYGSGGGYSSVFARPVWQDPANYSSQFRGVPDVSMLANPNTGVLMISG YRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTD--HSPFTRLDAATNNGNLYYVGQPGKVYN ++ YD GGTS +P +A + A+M+ ++ +GL +P Y ++ T + FT++ + +N YY +PG +N AKA----------------YD----------AGGTSLASPLWAGIIALMDQATNRSLGLVDPLFYQISNTRLYSNAFTQITSGSNG---YYNARPG--WN QAAGLGT GLGT PVTGLGT
Show aligned area	162448769	Sorangium cellulosum 'So ce 56'	protease	534	4e-11	0.25	0.36
ANNGLLIRVKGHVATINKAFAVNLKTARYH-----GKKIQ-FSKQAPRLPKQVAQPIRAVVGVTNLMI----------AKSLTTKSPAQVKHLTAKRSPT + N LL+ G V N AF L+ GK ++ F P P Q + I GV ++ I S+ + P +V+ +P SKNRLLLEFAGTVEQFNTAFDTELRDFERENPAAGGKPLRTFGALDPLRPPQ--RIIDLASGVISVEIPADTDPLPGEGGSIEEEPPQEVE---LGYTPA KFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYT---AKFSD + + Y L T+G G G +G++ T ++ FWR GV + T D E+ LD + +G +AP A++ Y A+ QIARVYGVEALHTAGHSGQGVKLGVVVGATFKTLDLQSFWRSFGVSRNNPEKVVTA------DPISTRYIESTLDMQWSGVMAPMAELIAYQGPDARTHS IGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGG I L A+ A A S LS S+ E R+ N GA G++ VASGD S+ P D P+ SP+VT GG I--LYAWNEAIAAGEVSVLSTSFAHREETEAQPIREQ---------YNEAARMGAALGMTIVVASGD-----------SSRP----DVPSSSPYVTCVGG STLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSG + L + G V RE W G SG G SR + TP +Q+ V + + TVLEL------GDGGEVAREVAWSG---------------------------SGSGRSRAFDTPWWQESV-----------------------VTDAQGT RNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDR R DV +A Y +Y W+ GGTS AP FA + A +NS R RAVSDVALSASSKFPYWLYFLGE-WDQRGGTSFAAPVFAGLMASVNSHR
Show aligned area	94967129	Acidobacteria bacterium Ellin345	protease-like	1223	1e-10	0.24	0.41
AKKKTVSLD---IVLKP--RQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG-LLIRVKGHVATINKAFAVN A +SLD ++L+P +Q+ L + TDS+++ +LTP+Q+ KFG + A ++T + ++ + + G I V G A + AF AVDSNLSLDRILVLLQPSAKQSDALKLYLDDLQNTDSKNYHQWLTPEQYAQKFGPTDADMQKVTDWLQSHGFKISEVAAGRQWIEVAGTAAQVRTAFNTE LKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTN----------LMIAKSLTTK-------SPAQVKHLTAKRS--------------PTKFLKQYHA + +GK + LP+ ++ +R V+ + N +++++ + K P LT S P K Y IHKYHLNGKDYFANASDVSLPRALSSVVRGVLSLNNFQKRSFTSHGVLVSRGTSGKLQPVAGVVPDSKGKLTVDPSYTLTTGNGSFHFLAPGDLQKIYDE SNLATSGQQGAGQTVGIISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDD-----SDDETALDAEQAGTIAPRAKVR-VYTAKFSDIGWLD + L T G G G ++ I+ ++ + + F + G+ + V+ NG D + E LD E AG AP AK++ V ++ + +D TPLLTDGNNGRGVSIAIVGRTNIELSDVHSFRQIFGL---------SENDPEVLINGTDPGITPDELEADLDLEWAGASAPGAKLKFVTSSSTASTDGVD AFTTAFAENR-ASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMP---GIEADFPADSPWVTATGGS ++R A +S S+G E L P ++L Q A +GI+ FV+SGD GA G + + +P G A +P+ A GG+ LSAAYIVDHRIAPIMSTSYGQCEA---------FLGPSGNAFYSSLWQQAAAEGITAFVSSGDNGAAGCD-PAAYFLPEQYGKMVSGLASTPYNVAVGGT TL L EL
Show aligned area	34497423	Chromobacterium violaceum ATCC 12472	protease	556	2e-10	0.23	0.38
KVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQ-ATAANNGLLIRVKGHVATINKAFAVNLKT ++A ++V + + LK R L L ++ S L+ +F A++ + A ++ + + + A N +LI +G AT AF L ELAAGQSVHVTVTLKLRNKAQLDALTDSLLAGTSHK---TLSHSEFMAQYAPTQAQVQKVVSHLQKSGFRNIKVAPNRMLITAEGSAATAKTAFNATLHH ARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRS-----PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA-- +G+ + A ++P+ + + AV G+ N+ + KS Q S PT F Y+AS+L + + TVGII+ G + FNVNGRSAFANVTAAQVPQSLGDTVLAVHGLQNVHTFHTTLRKSGVQTLASAKTNSVIGHNPTDFPLIYNASSLPPA----SNTTVGIIAEGDLTQTLQD IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDD-----ETALDAEQAGTIAPRA--KVRVYTA-KFSDIGWLDAFTTAFAENRASSLSLSWGLSENIL ++ F AG V++ GD S D E LD++ A A ++ Y A ++ A+ +A ++ A +++S G E LQQFEDSAGYSYVQ---------TNVINAGDASSDTDGVGEWNLDSQDILAAAGGALQQMNFYVATSMTNADITAAYNSAVSDGSAKVINVSLGECE--- RDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFK R D + I T +AQG +ST GD+G+ +E + G +PA SP+V A GG+T+ T + E W G RYAQSDGTIAS-DDQIFQTAVAQGQTFSVST----GDSGS-----AECGSTSG--QSYPATSPYVIAIGGTTVNTSGT------TKYSSETVWNG----- GYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGG +GGG S + P +Q AGV T + K R PDV +ADP +G + S ++ GG ----------------------TGGGPSVVEAAPSWQTK-AGVLTTSKTK--------------------RGVPDVSFDADPNSGALVIVNGSNQQI-GG TSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKL TS AP F A + S + NP +Y + + S + + + N G + ++ A G G++N L TSLAAPLFTGFWARIQSAHGNSLVSPNPAIYQYFKANPSLYHDVTSGNNGGY-----KATASWDYATGWGSLNVANL
Show aligned area	15922948	Sulfolobus tokodaii str. 7	hypothetical protein ST2611	599	2e-10	0.24	0.40
IVTSLVVGLICFGGIQGQAAKLVTVATPYRQSRLQHLYHVKKVAK-KKTVSLDIVLKPRQTKTLSQLALAVNTTDSQS--------------FKGYLTPQ IV LV+ L+ GI V++A +QS + LY+++ + V + ++P T T +A+ +N T+ S F +L+PQ IVGILVLILLMISGI-------VSIA---QQS--EQLYYIQTSSPIYSIVPGSVFVQPLNTSTELYIAVLLNFTNVSSLLNYLNEIYLSPSLFHKWLSPQ QFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQ----------------APRLPKQVAQPIRAVV QFR + S + + L Y + L GL + G+V I KAF + Y K + + Q P LP V + + +V QFREYYYPSQSYINSLVVYLESYGLHYDG-QYGLALVFNGNVGEIEKAFNTYINIYYYPFKDLYWFGQIGITDIGPFYYFSNNVTPSLPYNVGKYVLGIV GVTNLMIAKSLTTKSPAQVKHLTAKRSPTKF--------------LKQYHASNLATS-GQQGAGQTVGI--ISFGHVPTAAIKHFWRQAGVPTTGRLETK G+ SL K + +K K + T+ ++QY LA G G G + I + +V + I FW+ +P TG LE GI------DSLDPKVVSLIKQDAWKLNITRVGQGLISKVVISPLTIQQYFNFTLAYEHGLNGKGSDIAIEGVPECYVNVSDIYAFWKLYNIPRTGSLEVI TTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRV-----YTAKFSDIG-----WLDAFTTAFAENR--ASSLSLSWGLSENILRDLNRDHLLTPLYGD G T G +++E LDAE +G +P A V + Y + +G W + + + N + +S+S + E+ L P D MFGNDT--SGGQSAENE--LDAEWSGAFSPGANVTIVFSDGYVGGVNLVGNLLNYWYEYY---YMVNYLYPNVISISVSVPESYLA------AYYPAMLD IMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEAD-FPADSPWVTATGG +++ ++ Q A +GIS ASGD G + + + +P P+VT+ GG LIHNMMLQAAAEGISVLAASGDWGFESDHPPPNFRIGTYNTIWYPESDPYVTSVGG
Show aligned area	21241323	Xanthomonas axonopodis pv. citri str. 306	proteinase	653	2e-10	0.25	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKI VS D+ L R L L + S + +L+ F+ +FG + A +++ +A H+ T G + V + ++ + FA L G+++ VSFDVHLPSRDQVALDALLADIQDPLSPQYHKWLSAADFQRRFGPAPAQLAQVRAALQAAHM--TVVQQGPTLHVSANADSVERLFAAPLVADLKAGQQV QFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKF------------LKQYHA-----SNLATSGQQ----GAGQTVGIISFG + + AP + GVT + + L PA + P+ LKQ + + + GQQ G+G T+ I+ RLTAAAPLQLPAALR----AKGVTVTGLTRGL---PPAHMNSRLVASDPSNRYGDGTTSYWYNDLKQAYGYPSYQTMVGAPGQQRRLDGSGSTIAILIGS HVPTAAI------KHFWRQAGVPTTGRLETKT-TGGAT--VMDNGDDSDDETALDAEQAGTIAPRAKVRVYT-AKFSDIGWLDAFTTAFAENRASSLSLS V + I +HF R AG L + GA V D + E LD + A AP A V +Y S L + +N A +S S DVLDSDIATMFDHEHFSRYAGNHANPTLYARRYVAGAKPGVQDGNRAAAREATLDVDMALGGAPGAHVLLYVIPDLSIDSILAGYRQIVQDNEADVVSSS WGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY----GQNLSESSA---MPGIEADFPADSPWVTATGGSTLPIKKTFAPGISV +GL E + + T + G + +++ QG QGIS +SGD Q L E + +P +E +PA VTA GG L + FGLCEQVFTAAYNGNDATSILG-LFDSVFKQGNAQGISFVASSGDNAGLECPDTQYLVEGKSGRYIPSVE--WPAADAHVTAVGGGNL-----------L NVTRERTWGGDIFFKGYHQHPLQFIKHP----ILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSG--PKL-IHGYRSGRNYPDVVA ++ + + PLQ + P LL +GGG+S L+ P YQ G T + + L VG G P + +H + G TAYKKGSLDSTYLSESAFADPLQ-AEDPYGVGALLSGGYWGAGGGVSTLFQRPAYQLRALG-GTRTSMRALPDVGMLVGGCPGIAVHPCQQG-------- NADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT + IY + +++ GTS AP+FA++AA++ + R G N LY LA + R N V GK YN GLGT ----TSSVSIYVAGAITKVI-GTSVAAPEFASVAALL-VQKQGRQGNLNDYLYRLAANGPEAYHRGIPGNNGVVSNDVPIAGK-YNYTTGLGT
Show aligned area	94967490	Acidobacteria bacterium Ellin345	peptidase S8 and S53, subtilisin, kexin, sedolisin	1193	2e-10	0.22	0.37
PRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRA--CHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQFSKQA P Q L + + ++ +LTPQQF +FG + + +T++ R+ + + A N +++ H A ++ AF +L + +GK + PAQELELQKYLDDQKNPKATAYHHWLTPQQFGERFGSNGHDVATITQWLRSHGFTIDSVAKGNNVILFSGTH-AQLSAAFHTSLHQYKVNGKLQIANATN PRLPKQVAQPIRAVVGVTNLMI----------------AKSLTTKSPAQVKHLTAKRS-----PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAA P++P +A + + + + + AK +K Q + P F + Y+ L +G G GQ + I + A PQIPAALALAVVGIAKLNDFPLMPMHANFGGVTRHKGDAKWRPSKGAPQFNTKISGSDFFAVGPADFAEIYNVKPLWDAGIDGTGQNIAIAGRSDINPAD IKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVR-VYTAKFSDIGWLDAFTTAFAENR-ASSLSLSWGLSENILRDLNRD + F G+P +L GG GD+ E+ LD E +G IA A + V +A + ++ +N A +SLS+G E L D VDAFRSYFGLPAK-KLNVIYNGGNPGFQFGDEG--ESDLDIEWSGAIAKNATINFVASASTTTSDGVELSAQYIIDNALAPVMSLSYGECEVGLGDAG-- HLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTL----------------PIKKTFAPGISVNVTRE ++N L Q A +GI+ V++GD G+ + + A GI + +P+ A GG+ L P K A + -------NALINELWRQAAAEGITVMVSAGDAGSAACDQGQPFAGYGIAVNGLGSTPYNVAVGGTDLYGTYLNASNYWNATNDPTSKQSAKSYMPELPWN RTWGGDIFFKGYHQHPLQFIKHPILLEE------------------------LTAASGGGISRL---YGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKL + G Y Q + +P E T +SGG + Y P +Q GV G+ R + V +G L NSCGNPQLLAAY-----QSLGYPDKTTEDLCNDVDLAPYVANVVGGGGGASACTNSSGGDPTTCTDGYTKPAWQSGVPGIPADTVRD-IPDVSLFAGSGL ---IHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHS + + PD+ N D +G D+ + GGTS +P FA + A++N + G N LY LA +S WGSFYVFCESDVTPDLACNLD--SGDDVQMLAA-----GGTSFASPAFAGVMALVNQKTNSSQGNANYDLYKLAGKQYS
Show aligned area	197295253	Burkholderia cenocepacia J2315	serine-carboxyl peptidase	411	3e-10	0.26	0.37
IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIKHFWRQAGVPT + F++ +PR P+ A+P + G ++PA + SP + + Y L G G Q V I+ P A ++ F R G+P VSFAQSSPRAPRGFARPPLHLHGAAK---------RNPAGL-------SPQQIRRFYGFDQLPARGYGGDDQVVAIVDAYDNPNVEADLRTFSRTFGLPP TGRLETKTTGGATVMDNGDDSDD----ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENR--------ASSLSLSWGLSENILRDLNRDHL T AT D E++LD + A IAP A++ + A S LD +A A A +S+SWG E + CASPRCFTKVYATADKRPPPPDALWALESSLDVQWAHAIAPNARIVLVEAASSS---LDDLMSAIALATSPAPGGVGAKVVSISWGSGEFLAE------- LTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQ T G + G+S ASGD G GI D+PA SP+V + GG+++ A S E W G -TQFDGQF-------ASANGVSFVAASGDGGN------------GI--DYPAASPYVLSVGGTSI------ATDASGAYAGETAWAG------------- FIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI-----YSKNSGWELMGGTSA SGGG S + P YQ N R ++G R PDV +ADP +G+ + Y+ GW ++GGTSA --------------SGGGQSAVETEPTYQS--------NFRIPSDSLGL-------------RGLPDVAYDADPASGFAVYDSYGYAGQGGWFVVGGTSA VAPQFAAMAAVMNSDR APQ++A+ A+ NS R GAPQWSALIAIANSLR
Show aligned area	146303098	Metallosphaera sedula DSM 5348	peptidase S8 and S53, subtilisin, kexin, sedolisin	600	3e-10	0.23	0.39
LIVTSLVVGLICFGGIQGQAAKLVTVATPYRQSRLQHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTS L+ +SL GL+ +Q Q + + + S L V+ + T+ + I+L +L+ L V ++ YLTP +FR + S + + LVFSSLGSGLV----LQAQESMYYVQTSSPQYSILPGSQFVEPLNTGLTIPIAILLNFTNYSSLNSELLYVISSGH-----YLTPLKFREYYYPSQSYVN RLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKIQF----------------SKQAPRLPKQVAQPIRAVVGVTNL--------- L Y T N GL++ V I +AF + Y K I + + P LP V + + +VG+ NL SLENYLEGYGFVPTG-NYGLILTFNATVGEIEQAFHTYINVYYYPFKDIYWFGKVGEKRVGPFYYFTNNVTPSLPYGVGKYVLGIVGIDNLDPHAYQGLR ---MIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGI--ISFGHVPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDE + + S + +A +P + ++ S+L G+ G+G T+ I + +V T I FWR +P TG T G D E QAWNVPMTEGKGSSSSGLISSAIFTPNTIQQYFNFSSLYAQGKTGSGSTIAIEGVPECYVNTTDIYSFWRLFNIPRTGSFNVITLGN----DTSGGQSGE TALDAEQAGTIAPRAKVRVYTAKFSDIGWL--DAFTTAFAENRASSLSLSWGLSENILR---DLNRDHLLT--PLYGDIMNTLLAQGAIQGISTFVASGD LDAE +G AP A + + FSD G++ A ++ L+ +++ L +L P +++ ++ Q ++QG S ASGD NELDAEYSGAFAPGANIAIV---FSD-GYVGGKALVGNLLNYYYEYYYMANYLNPDVVSISVSLPESYLAAYYPAMLYMIHNIMVQLSVQGTSVLAASGD TGAYGQNLSESSAMPGIEAD--FPADSPWVTATGG G + N + G+ +P P VT+ GG WG-FESNHPPPNFHIGVYNTIWYPESDPLVTSVGG
Show aligned area	146303488	Metallosphaera sedula DSM 5348	peptidase S8 and S53, subtilisin, kexin, sedolisin	1072	5e-10	0.23	0.39
HVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNL V + + V++ IV KP + L+ L L V Q K LT Q + F + +L Y + + + N +I G V+ KA + QVSTLPPSQLVTVSIVEKP---QNLALLQLYV-----QEHK-VLTKDQVESLF-VPTEKIQQLVNYLHGYGIATSVSLN--VITATGTVSQFEKALGGSF KTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKH ++H + F + V+ + VT ++ + T + Q + + +P++ Y+ + L G G T+GI+ F P ++ YVEKFH--NLTFYQYVDVSSPLVSNALVFSTNVTTSLLQRPSTLINVTQAVAFS-QVTPSQLRYAYNVTPLLHKGINGTNVTIGIVDFYGDPYIQQQLQE FWRQAGVPTTGRLETKTTGGATVMDNGDDS-DDETALDAEQAGTIAPRAKVRVYTAKFSD-----IGWLDAFTTAFAENRASSLSLSWGLSENILRDLNR F + + ++ G D E +LD E A +AP A + +Y A + I ++D +++ S +S S+G+ E L FDSNYNISNPPFFKVESIGAYNPNDGISSGWALEISLDVEYAHVLAPGAGIILYVANPNASLPQVIAYIDQ------QDQVSVVSQSFGIPE-----LYV DHLLTPLYGDIMNTLLAQ---GAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGY L PL ++ +L + G ++GI+ +SGD G G N S P PA P+V A GG+++ S ++ W G ALGLIPL--SMVQSLTYEYWLGEVEGITFVASSGDAGGNGYNFYLS---PLGNLVLPASDPYVLAVGGTSVYY--------SNGSVKQTAWSG------- HQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTS E L AS GG S ++ +P YQ HG+R PDV A+A+P TG + + EL+GGTS --------------ESLFGASTGGYSVIFPSPWYQGS-------------------------HGFRM---VPDVAADANPYTGVPVTYYYNISELVGGTS AVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQT +P A + A + ++G NP +Y+L T VASPLVAGILA-LAVQVHGKLGFINPLIYSLNGT
Show aligned area	115361122	Burkholderia ambifaria AMMD	hypothetical protein Bamb_6381	410	8e-10	0.25	0.36
IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIKHFWRQAGVPT + F++ APR P A+P L PA K SP + Y L G G Q + I+ P A ++ F G+P VSFAQHAPRAPHAFARP--------------PLHLHGPA--KRNPVGLSPQRIRSFYGFDQLPARGYGGDDQVIAIVDAYDNPNVEADLRSFSSTFGLPP TGRLETKTTGGATVMDNGDDSDD----ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLD-----AFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTP T AT D E++LD + A IAP A++ + A S + L A T A A A +S+SWG S L + D CASPHCFTKIYATPDKRPPPPDALWALESSLDVQWAHAIAPNARIVLVEAASSSLDDLMSAIALATTPAPAGPGAKVVSISWG-SPEFLAETQFDGQF-- LYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIK + G+S SGD G GI D+PA SP+V + GG+++ A S E W G ------------ASANGVSFVAGSGDGGN------------GI--DYPAASPYVLSVGGTSI------ATDASGAYAGETAWAG---------------- HPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI-----YSKNSGWELMGGTSAVAP SGGG S + P YQ + G+ P L R PDV +ADP +G+ + Y+ GW ++GGTSA AP -----------SGGGQSAIEPEPTYQSNL-GI-------------PSDSLGL-------RGVPDVAYHADPASGFAVYDSYGYAGQHGWFVVGGTSAGAP QFAAMAAVMNSDRSQR-------MGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLG Q++A+ ++ NS R R +G + LY LA + + R + +NG + Y+ GLG QWSALISIANSVRVARGKTTLNAVGAIHTVLYGLASSASATNFRDIVSGSNGACGTLCTATAGYDYVTGLG
Show aligned area	73541448	Ralstonia eutropha JMP134	kumamolisin	551	1e-09	0.25	0.43
LTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG-LLIRVKGHVATINKAFAVNLKTARYHGK-KIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKS L+ ++ +FG + T ++ R LQ G IRV+G + + AF L G+ +I+ +P ++A + V G+ +AK LSREEIVQRFGVPAETVRKVEDVLRGYGLQVVEVKQGGRSIRVRGTASAMIAAFKPELGIYHVPGQGQIRARHGVLMVPGEIADVVEGVFGLDQRQMAKR LTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGH-------VPTAAIKH----FWRQAGVPT-TGRLET-------KTTGGATVM ++ A V+ L +P +K+YH + GA +T+ I FG +P A + F ++ G+P R+E+ + A + -HAQAAALVRTLVP-LTPADLVKRYHFPD-----GDGADRTIAIAEFGQNIGNGQVLPPAYLPSDVSLFCKRQGLPVPVVRIESVGLSPLSEQQFRAEIQ DNGDDSDD-------ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAF--TTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAI + D D ET +D E + P+A + VY A + + GW++ T+ +LS+S+GL+E D + + + +N L A+ ELPKDLQDLLFVQTAETMMDIEIVAGLCPKADIGVYFATWGESGWINLLDEVTSGKGPVPVALSISYGLAEEA-TDWSHGAMAS------INQRLQIAAM QGISTFVASGDTGAYGQNLSESSAMPG--IEADFPADSPWVTATGGSTL QG++ V+SGD G+ G N PG FP SP+V + GG+ L QGVTVCVSSGDDGS-GCN------QPGKRCHVAFPTSSPYVLSVGGTML
Show aligned area	115350820	Burkholderia ambifaria AMMD	curculin domain-containing protein	788	5e-09	0.23	0.36
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHL-QATAANNGLLIRVKGHVATINKAFAVNL-KTARYHGK V + +VLK L++ T S F LT Q A++ ++A + + Y + A+N +++ I+ F L A G VHVALVLKLNDEAGLNRFIEHARTPGSAGFGAVLTSAQIAAQYAPTTAQVATVKAYLASKGFTNIKVADNNMIVEADAPAGVISGVFRTTLVPVAMADGT KIQFSKQAPRLPKQVAQPIRAVVG-----------VTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPTAAIK + +P ++ +R V+G V A + T + + +T +PT+F Y + T+ A T+GII+ G V + I GTHINTAPETVPDAISGVVRGVLGLDTATRLRPNFVRASNAAAAPTANASPTISAVTVGHNPTQFPGIYSVGSTPTA----ANTTIGIIAEGDVTQSVID --HFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQ-AGTIAPRAKVRVYTAKFSDIGWLD---AFTTAFAENRASSLSLSWGLSENILRDLN F +P + A + ++ E +LD++ G ++ Y A+ W D A A ++N A +++S G EN LATFESHNQLPAV----PVSVIHAGLASADTSANIEWSLDSQTIVGMSGGLKQLNFYVAR--SFAWSDIALAINRAVSDNTARVINMSIGGCENWAPTAA RDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQ D L +AQG Q S + AYG N G +PA SP+V A GG+TL + G + N E W IDTLF--------QLAVAQG--QTFSVSSGDSGSVAYGCN--------GTSVQYPATSPYVVAVGGTTL-----YTNG-NGNYAGETAW----------- HPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAV ASGGGIS P +Q V + R+ R PD+ +ADP +G I E +GGTS ----------------EASGGGISGFEPIPSWQSNVPALKG----------------------RASRGMPDLAFDADPNSGAQIIVGGQ-LETVGGTSLS APQFAAM-AAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGTVNFEKLARS AP F+A A +++ + +G P++Y++ T S F + TN N Y G ++ G GT N L S APLFSATWARLLSGSCTTSLGFAAPRIYSVQSTTASIFHDI---TNGSNGAYSAGSG--WDFVTGWGTPNVSLLYSS
Show aligned area	159040594	Caldivirga maquilingensis IC-167	protease-like protein	781	6e-09	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E+ LD E IAP A++ + + E+ + +SLSWGLSE+ L P Y + + Q A QGI F +SGD+GAY ESVLDNEWVHAIAPGARIVFGVSPDAGDDLYVTIEYMVNESLVNFISLSWGLSED---------YLDPYYALAYDQIFMQAAAQGIGVFASSGDSGAY-- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQG---- P + A P+ PWVT GG+T PG S +T W F + P I SGGG S + P YQ -----EFYPFVSAFHPSIDPWVTGVGGTT----SYLFPGGSRFIT---AWS----FYSFGLPPWDLI---------YWGSGGGYSIFFDMPLYQYQYIFN -VAGVNTYNARKYLTAV-GPKSGPKLIHG--------------YRS--------------GRNYPDVVANADPITGYDIYSKNSGWELM-GGTSAVAPQF + N Y ++ + G G ++ YR+ + YP V A+A+P TG I + GGTS +P LIGEGNFYEQTQFQPLIWGLLLGQFFVNEPYVPTLNINPYTPLYRTFEWMLYPSLYVPIGAKGYPIVSADANPYTGVLIVIDGELNPFIWGGTSLASPLT AAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVY M A+ D + G+ P LA S +A ++ N YY P VY MGMVALWQ-DYLNKAGI--PYQVGLAAVPLSQIWATEAGSSFCNAYY---PTSVY
Show aligned area	134294974	Burkholderia vietnamiensis G4	peptidase S8 and S53, subtilisin, kexin, sedolisin	404	8e-09	0.25	0.39
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRD-HLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYG E +LD E IAP+AK+ + A + L A + AS +S+S+G +E + D H P G++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASASFTDLMAAVDVAVKRGASVVSMSFGGNEFFSGETAYDGHFNVP----------------GVTFVASSGDSGT-- QNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAG ++PA SP+V A GG+TL + A G N E W ++SGGG+S G P Q G ------------GTEYPAASPYVVAVGGTTLSVD---AAG---NYVGEAAW---------------------------SSSGGGVSTAEGQPAGQAG--- VNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRS----QRMGLWNPQLYAL P + G R PDV +A+P +G+ +Y +GW +GGTSA APQ++A+ A+ NS R+ R+ LYA+ -----------------WPIPVAG---KRGVPDVGYDANPSSGFAVYDSVTYQGQAGWFQVGGTSAGAPQWSALVAIANSLRTAAGKSRLSGTYDMLYAI AQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT ++ + +NG+ + Y+ GLG+ GKSAYGSDYHDVTIGSNGSCGSICNAAGGYDYVTGLGS
Show aligned area	172065360	Burkholderia ambifaria MC40-6	hypothetical protein BamMC406_6083	404	9e-09	0.25	0.36
IQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQTVGIISFGHVPT--AAIKHFWRQAGVPT + F++ APR P A+P L PA K SP + Y L G G Q + I+ P A ++ F G+ VSFAQHAPRAPHAFARP--------------PLHLHGPA--KRNPVGLSPQRIRSFYGFDQLPARGYGGDDQVIAIVDAYDNPNVEADLRLFSSTFGLSP TGRLETKTTGGATVMDNGDDSDD----ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLD-----AFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTP T AT D E++LD + A IAP A++ + A S + L A T A A +S+SWG E + T CASPRCFTKVYATPDKRPPPPDALWALESSLDVQWAHAIAPNARIVLVEAASSSLDDLMSAIALATTPAPVGPGAKVVSISWGTPEFLAE--------TQ LYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIK G + G+S SGD G GI D+PA SP+V + GG+++ A S E W G FDGQF-------ASANGVSFVAGSGDGGN------------GI--DYPAASPYVLSVGGTSI------ATDASGAYAGETAWAG---------------- HPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDI-----YSKNSGWELMGGTSAVAP SGGG S + P YQ + G+ P L R PDV +ADP +G+ + Y+ SGW ++GGTSA AP -----------SGGGQSAIEPEPTYQSNL-GI-------------PSDSLGL-------RGVPDVAYHADPASGFAVYDSYGYAGQSGWFVVGGTSAGAP QFAAMAAVMNSDRSQR-------MGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLG Q++A+ A+ NS R R +G + LY A + + R + +NG + Y+ GLG QWSALIAIANSVRIARGKTALNAVGAIHTVLYGFASSASATNFRDIVSGSNGVCGTLCTATAGYDYVTGLG
Show aligned area	172059871	Burkholderia ambifaria MC40-6	peptidase S8 and S53 subtilisin kexin sedolisin	403	1e-08	0.24	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+A++ + A + L A ++ AS +S+S+G +E H P G++ +SGD+G EISLDVEWVHAIAPKARILLVEAASASFNDLLAAVDVAVKHGASVVSMSFGGNEFNTETGFDSHFNVP----------------GVTFVASSGDSGT--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S + P Q G -----------GTEYPASSPYVVAVGGTTL------STDTSGNYIGEAAWSG---------------------------SGGGVSTIEAEPAGQTG---- NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRS----QRMGLWNPQLYALA + V K R PDV +A+P +G+ +Y +GW +GGTSA APQ++A+ A+ NS R+ + LY + -------WPVPVAGK------------RGVPDVSYDANPSSGFAVYDSVTYQGQAGWFQVGGTSAGAPQWSALVAIANSLRAAAGKHALSGTYDTLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT ++ + +NGN V Y+ GLG+ KSAYGSDYHDVTTGSNGNCGSVCNAAGGYDYVTGLGS
Show aligned area	83721436	Burkholderia thailandensis E264	serine protease	406	1e-08	0.27	0.38
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVAS-GDTGAYG E +LD E IAP+AK+ + A + L A AS +S+S+G SE H P + TFVAS GD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDAAVGAGASIVSMSFGGSEFSSETGFDSHFSAPSH----------------VTFVASSGDSGN-- QNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAG ++PA SP+V A GG+TL + S N E W G SGGG+S ------------GTEYPAASPYVVAVGGTTLAVDA------SGNYIGETAWSG---------------------------SGGGVS-------------- VNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQ--RMGLWNP--QLYAL TY A+ P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ + L P QLY + --TYEPEPSGQALWPIP-------YAGSRGVPDVAYDANPSSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRAAAGKATLAGPYNQLYTV AQTDH-SPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT + + S + + + TN G G Y+ GLG+ GKLAYGSDYHDITSGTNGGCGTICTASGS-YDYVTGLGS
Show aligned area	13541953	Thermoplasma volcanium GSS1	serine protease	1097	1e-08	0.25	0.38
PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKFS P + K Y G G G+T+ II P + F G+P + GA N + ET+LD E A AP AK+ + + PAQIYKAYSYGWDIAHGINGKGETIAIIDAYGDPFLNYDLNAFDSITGLPP-ANISVIYLDGAGAQYN-EHWAQETSLDVEWAHVSAPLAKIILVVSPND DIGWLDAFTTAFAEN-RASSLSLSWGLSENILRDLNRDHLLTPLYG-DIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTA + L A +N + S +SLSWG++EN L P+ ++MN++ +GI+ ASGD GAY + +FPA SP+V SVLSLTAAVAYVIQNIKTSVISLSWGIAENQL----------PISQIELMNSMYLNATKKGITIVAASGDYGAYDNT-------KNLTVNFPASSPYVLG TGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPK-YQQGVAGVN-TYNARKYLTAVG-PKSGPKLI GG++L +S + R+ W + S G P+ Y Q G N TY ++ + P +G +I VGGTSL--------FLSNGIFRQSAW----------------------GGTSSQGSFGSGGGFSSFPRPYWQIAPGYNSTYRGVPDVSMIANPNTGVLMI HGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTD--HSPFTRLDAATNNGNLYYVGQPGKV G ++ YD + L G A+ Q+ + +GL NP LY L+ T +S FT++ T N YY PG SGAKA----------------YDAGGTSLAAPLWAGVIAMMDQY----------DNTTLGLVNPILYQLSNTPLYNSTFTQI---TTGYNGYYSAAPG-- YNQAAGLGT +N GLGT WNPVTGLGT
Show aligned area	115350858	Burkholderia ambifaria AMMD	peptidase S8 and S53, subtilisin, kexin, sedolisin	403	2e-08	0.25	0.38
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSE-NILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYG E +LD E IAP+A++ + A + L A + AS +S+S+G +E N +R H P G++ +SGD+G EISLDVEWVHAIAPKARILLVEAASASFNDLLAAVDIAVKRGASVVSMSFGGNEFNTETGFDR-HFNVP----------------GVTFVASSGDSGT-- QNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAG ++PA SP+V A GG+TL + S N E W G SGGG+S + P Q G ------------GTEYPASSPYVVAVGGTTL------STDTSGNYIGEAAWSG---------------------------SGGGVSTIEAEPAGQTG--- VNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRS----QRMGLWNPQLYAL + V K R PDV +A+P +G+ +Y +GW +GGTSA APQ++A+ A+ NS R+ + LY + --------WPVPVAGK------------RGVPDVSYDANPSSGFAVYDSVSYQGQAGWFQVGGTSAGAPQWSALVAIANSLRAAAGKHALSGTYDTLYTV AQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT + + +NGN V Y+ GLG+ GKNAYGSDYHDVTTGSNGNCGSVCNAAGGYDYVTGLGS
Show aligned area	121598221	Burkholderia mallei SAVP1	serine protease	406	6e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	126450743	Burkholderia mallei NCTC 10247	putative lipoprotein	406	6e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	124384681	Burkholderia mallei NCTC 10229	serine protease	406	6e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	53725911	Burkholderia mallei ATCC 23344	serine protease	406	6e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	53720249	Burkholderia pseudomallei K96243	hypothetical protein BPSL2639	406	6e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	76811314	Burkholderia pseudomallei 1710b	hypothetical protein BURPS1710b_3113	406	6e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	126453435	Burkholderia pseudomallei 1106a	putative lipoprotein	406	6e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	126441291	Burkholderia pseudomallei 668	putative lipoprotein	406	7e-08	0.26	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L AS +S+S+G SE H GA ++ +SGD+G EMSLDVEWVHAIAPKAKIVLVEAASNSFNDLMTAVDVAVGAGASVVSMSFGGSEFSSETSFDSHF---------------GAPSNVTFVASSGDSGN--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA SP+V A GG+TL + S N E W G SGGG+S Y+ -----------GTEYPAASPYVVAVGGTTL------SADASGNYVGETAWSG---------------------------SGGGVS------AYE------ NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNP----QLYALA L VG P Y R PDV +A+P +G+ +Y SGW ++GGTSA APQ+AA+ A+ NS R+ QLY + --------LEPVGQTLWPI---PYAGQRGVPDVAYDANPNSGFAVYDSVTYQGQSGWFVVGGTSAGAPQWAALFAIANSMRTAAGKAKLAGAYNQLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + + NG+ + Y+ GLG+ KTAYGSDYHDVTSGTNGSCGMICTASGGYDYVTGLGS
Show aligned area	94967136	Acidobacteria bacterium Ellin345	protease-like	1478	1e-07	0.22	0.36
IVLKP--RQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNG-LLIRVKGHVATINKAFAVNLKTARYHGKKIQ +VLKP Q +L +L + S + +LTP++F A +G S +++ + + + + NG I G + AF +L +G++ LVLKPSAEQQASLQRLLDSQQNKKSPNHHKWLTPEKFAASYGPSEEDVAKVKNWLESQGMSVSKIGNGRQWIEFSGSAHQVGTAFGTSLHYFETNGERHM FSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKR---------------------SPTKFLKQYHASNLATSGQQGAGQTVGIISFGH + +P+ ++ + V+ + N K T ++VK + +PT K Y+AS L G G G ++ + + ANATEISIPRAISPVVSGVLSLHNFH--KQPNTSKLSKVKLGDDGKLAPVDPAWTYRDYNLNPYYYLAPTDAQKIYNASPLLNDGVDGTGISIAVAGRSN VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMDNGDDSDD------ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASS--LSLSWGL + + ++ F G+ + NG D E LD E A +AP A + + +D + A+ + A + +++S+GL IYLSDVQLFRNVFGLKQN---------DPNFIVNGPDPGYPFGDLVENTLDVEWASAMAPGATINFVASGSTDTTDGVDLSAAYIVDNAVAPIVTVSYGL SENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY--GQNLSESSAMPGIEADFP------ADSPWVTATGGSTLPIKKTFAPGISVNV E L+ P N+L AQ A QG++ FV++GD GA +L + P A + + +P+ A GG+ F S N CEA---------LMGPASNQFYNSLWAQAAAQGMTVFVSTGDVGAAECDGDLQRAGYDPPGPAQYGPTISGLSSTPYNVAVGGTQYNEGSNFGQYWSPN- TRERTWGGDIFFKGY-HQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAG-------VNTYNARKYLTAVGPKSGPKLIHGY----RSGRNYPD + T+G + GY + P L +E G + +YG Y G +T + + +T V P G R+ PD -NDSTFGSVL---GYVPEQAWNESCDPNLPQE-------GTNCVYGQTNYNLDGGGGGPSNCSQSTVDDQGLITCVAGTPKPSWQTGLGVPNDGVRDTPD VVANADP-----------------ITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPF----TRLD-AATNNGNL + NA P + G I + S +GGTSA P A + A++ G N Y LA D R D AT+ N LSLNASPDDDGFLFCLIGGCQTTTVNGQTILTNAS---TIGGTSASTPAMAGIMALIEQKNGAFQGQANYIFYKLAAMDDQAACDSSKRTDPTATSTCNF YYV--------GQPG-----------KVYNQAAGLGTVNFEKLARSY V G PG Y+ A GLGTVN +A ++ NDVTMGSNSVPGLPGYGTDSAEWSATTGYDMATGLGTVNAANIATNW
Show aligned area	70607986	Sulfolobus acidocaldarius DSM 639	hypothetical protein Saci_2277	1281	1e-07	0.24	0.38
PTKFLKQYHASNLATSGQQGAGQTVGIISFGHVP--TAAIKHFWRQAGVPTTGRLETKTTGGATV-MDNGDDSDDETALDAEQAGTIAPRAKVRVYTAKF PT K Y+ ++L + G +G T+GI+ F P + ++ +P G + D E +LD E A T+APRA + +Y A PTALQKVYNLTSLYSKGYEGQNFTIGILDFAGNPYIQQQLAYYDSIVKLPNPPNFTIVPIGPYNPGLGIATGWDSEISLDVESAHTMAPRANMVLYIAN- SDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGD---IMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWV L+ +A ++ + + + P+Y + + A G+++GI+ +SGD G G + + PG +P+ SP+V -----LNLPLSAVIAYIDQQHKVNIISQSFSISESSLSSYPAPIYYTNIALTDVYYALGSVEGITFIASSGDVGGSGYS-NGPLGTPG----YPSTSPYV TATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIH + GG+T I+ P S T +G F+ P + G I + P YQ G+ PK+ LSAGGTTTYIQ---FPNGSFYQTAWSNYG--------------FV--PNGVNYGGGTGGVSI--VEPKPWYQWGIT--------------SPKT------ GYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQ Y +GR PDV ANA+ G I + + GGTS +P A M + S + +GL NP LY + + T N+ + G YN -YPNGRLGPDVSANANVYPGIYIIGGFNQTLITGGTSEASPLLAGMLVAVMSYVNHSLGLINPLLYQIGENPQLYSKIFYPITFGYNIPWTSSYG--YNL AAGLGTVNFEKLAR A G G +N + A+ ATGWGALNAGEFAQ
Show aligned area	170732259	Burkholderia cenocepacia MC0-3	peptidase S8 and S53 subtilisin kexin sedolisin	405	2e-07	0.24	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L A + AS +S+S+G +E H P G++ +SGD+G EISLDVEWVHAIAPKAKIVLVEAASASFSDLLAAVDVAVKRGASVVSMSFGGNEFSSETGFDGHFNVP----------------GVTFVASSGDSGT--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV G ++PA S +V + GG+TL + + N E W G SGGG+S + P ---------GTGTEYPAASRYVVSVGGTTL------SSDTAGNYIGEAAWSG---------------------------SGGGVSNVEAEP--------- NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRS----QRMGLWNPQLYALA G + P + G R PDV +A+P +G+ +Y +GW +GGTSA APQ++A+ A+ NS R+ + + LY + -----------AGQTAWPIPVAG---KRGVPDVSYDANPSSGFAVYDSVTYQGQAGWFQVGGTSAGAPQWSALVAIANSLRTAAGKKSLSGTYDTLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + +NGN + Y+ GLG+ KTAYGSDFHDVTTGSNGNCGSICNAAGGYDYVTGLGS
Show aligned area	78046139	Xanthomonas campestris pv. vesicatoria str. 85-10	secreted protease	624	3e-07	0.24	0.39
VSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQATAANNGLLIRVKGHVATINKAFAVNLKTARYHGKKI VS D+ L PR L+ L + S + +L+ +F+ +FG + A +++ +A H+ T G + V + ++ + FA L G+++ VSFDVHLPPRDQVALNALLADIQDPLSPQYHKWLSAAEFQRRFGPAPAQLAQVRAALQAAHM--TVVQQGPTLHVSANADSVERLFAAPLVADLNAGQQV QFSKQAPRLPKQVAQPIR-AVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKF----LKQYHA-----SNLATSGQQ----GAGQTVGIISFGHVPTAAI + + AP + V G++ + A + ++ A T + LKQ + + + G+Q G+G T+ ++ V I RLAAAAPLQLPAALRANGVTVTGLSRGLPAARMDSRMLAGTPGNRTGDGTTSYWYNDLKQAYGYPSYQTMIGAPGKQQRLDGSGSTIAVLIGSDVLDTDI ------KHFWRQAGVPTTGRLETK--TTGGATVMDNGDDSD-DETALDAEQAGTIAPRAKVRVYT-AKFSDIGWLDAFTTAFAENRASSLSLSWGLSENI + F R AG L + G + G+ + E LD + A AP A V +Y S L + +N A +S S+G E I AAMFDHERFSRYAGNHANPTLYARRYVAGAKPGVQGGNRAAVREATLDVDMALGGAPGAHVLLYVIPDLSIDSILAGYRQIVQDNEADVVSSSFGFCEQI LRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYG----QNLSESSA---MPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERT T + G + +++ QG QGIS +SGD Q L E +P + +PA VTA GG L + ++ + FTAAYNGKDATSILG-LFDSVFKQGNAQGISFVASSGDNAGLDCPDTQYLVEGKNGRYVPSVH--WPAADAHVTAVGGGNL-----------LTAYKKGS WGGDIFFKGYHQHPLQFIKHP----ILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSG--PKL-IHGYRSGRNYPDVVANADPITG + PLQ + P LL +GGG+S L+ P YQ G T + + L VG G P + +H + G + LDSSYLSESAFADPLQ-AEDPYGVGALLSGGYWGAGGGVSTLFQRPAYQLRALG-GTRTSMRALPDVGMLVGGCPGIAVHPCQQG------------TSS YDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT IY + +++ GTS AP+FA++AA++ + R G N LY LA + R N V GK YN GLGT VSIYVAGAITKVI-GTSVAAPEFASVAALL-VQKQGRQGNLNDYLYRLAANGPQAYHRGIPGNNGVVGNDVPIAGK-YNYTTGLGT
Show aligned area	16082551	Thermoplasma acidophilum DSM 1728	multitransmembrane protein	1350	4e-07	0.23	0.39
QHLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQA-TAANNGLLIRVKGHVATINKA Q+L ++ +++ + L L Q VN+ S F YLTPQ+F A + S + S++ Y+ A + + A L+I ++G V +A QYLLNLGPANPDNVINVTLYLNMTNLSQLEQFVALVNSPMSPYFHDYLTPQEFMASYYPSQSQISQVESYYSAMGFRVWSYAYTPLVIVLQGTVGMFERA FAVNLKTARY-----HGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIA--------------KSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQ F L + G + P +P Q + I V G++ A ++T + + + +P + Y+ + L G FGTMLFNFEFTYPGGSGAVFMTNTANPYIPAQFSGLIMHVYGLSYSSEALLSTQNRQDLKTEVSGISTLTDQNLNGSSNILTPVHLAQFYNVTGLEQLGF QGAGQTVGIISFGHVPT-AAIKHFWRQAGVPTTGRLETK-TTGGATVMDNGDDSDDETALDAEQAGTIAPRAKV G G +GI+ G +AI FW Q G+ + T G G ++D LD E +G +AP A + TGKGVKIGILGVGESANMSAISMFWDQYGIHHPQVVFVNLTPNGMNPYPEGVEAD----LDVEWSGAMAPNATI
Show aligned area	148271681	Clavibacter michiganensis subsp. michiganensis NCPPB 382	serine protease	625	5e-07	0.26	0.39
DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY- DE LD + +AP A V + A L AE+ +SLS+G E + +R+ ++N +L + A + +S F ++G+ G Y DEQHLDVQAVHAMAPDATVSYWGADDCTSTSLYTRILDAAEDGPDVISLSFGAMEGLDTADDRE---------LLNRVLVEAASRDVSVFASTGNDGDYS -----GQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGI-SRLYGTPK G N + +S PA SP+VTA G ++ + + G I + + +F ++ L+ A GG S Y P GVGDHGGNATVAS---------PASSPYVTAVGATSTGLAED----------------GSIAVEAGWETQTRFARNGALIPPGFAFGAGGGHSAEYARPT YQQ---GVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSG---WELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQ +Q VAG +GR PDV + DP TG+ Y + G + GGTS P A+M A+ + +R GL +P WQADRLAVAG--------------------------TGRLLPDVASLGDPDTGFITYGPHKGRTEYAAHGGTSLATPMVASMVAISKAVTGRRFGLASPA LYALAQT LYAL T LYALMGT
Show aligned area	13540979	Thermoplasma volcanium GSS1	multitransmembrane protein	1344	5e-07	0.24	0.41
HLYHVKKVAKKKTVSLDIVLKPRQTKTLSQLALAVNTTDSQSFKGYLTPQQFRAKFGQSSATTSRLTRYFRACHLQA-TAANNGLLIRVKGHVATINKAF +L ++ + +++ + L + L Q VN+ +S F+ YL+P QF + + SS+ + + Y+ + + L+I ++G+V+ AF YLLNLGPANQSTVINVTLYLNFTHIQALEQFVSQVNSPNSPEFRHYLSPSQFESMYYPSSSVINSIENYYEKLGFKVWSYWYAPLVIVLQGNVSMFEHAF AVNLKTARY-----HGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIA-KSLTTKSPAQVKHLTAKRS------------PTKFLKQYHASNLATSGQQG L + G + P +P + I V G++ A S K + + T K S P Y S L SG G GTMLFEYMFTYPGGDGAVFMTNTANPYIPIEFKGVIMHVYGLSYSSDALLSTVNKHELKTEVSTVKLSGLNLNGSKDLLTPINLANFYGVSALEESGLTG AGQTVGIISFGHVPT-AAIKHFWRQAGV--PTTGRLETKTTGGATVMDNGDDSDDETALDAEQAGTIAPRAKV AG +GI+ G +AI +FW Q G+ PT + T G G ++D LD E +G +AP + + AGIKIGILGVGESANISAIDNFWNQYGIHHPTV-KFVNLTPNGLNPYPEGVEAD----LDVEWSGAMAPNSTI
Show aligned area	116688968	Burkholderia cenocepacia HI2424	peptidase S8 and S53, subtilisin, kexin, sedolisin	403	8e-07	0.23	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L A + AS +S+S+G +E H P G++ +SGD+G EISLDVEWVHAIAPKAKIVLVEAASASFSDLLAAVDVAVKRGASVVSMSFGGNEFSSETGFDGHFNVP----------------GVTFVASSGDSGT--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA S +V + GG+TL + + N E W G SGGG+S + P -----------GTEYPAASRYVVSVGGTTL------SSDTAGNYIGEAAWSG---------------------------SGGGVSNVEAEP--------- NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRS----QRMGLWNPQLYALA G + P + G R PDV +A+P +G+ +Y +GW +GGTSA APQ++A+ A+ NS R+ + + LY + -----------AGQTAWPIPVAG---KRGVPDVSYDANPSSGFAVYDSVTYQGQAGWFQVGGTSAGAPQWSALVAIANSLRTAAGKKSLSGTYDTLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + +NGN + Y+ GLG+ KTAYGSDFHDVTTGSNGNCGSICNAAGGYDYVTGLGS
Show aligned area	107022024	Burkholderia cenocepacia AU 1054	peptidase S8 and S53, subtilisin, kexin, sedolisin	403	8e-07	0.23	0.37
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQ E +LD E IAP+AK+ + A + L A + AS +S+S+G +E H P G++ +SGD+G EISLDVEWVHAIAPKAKIVLVEAASASFSDLLAAVDVAVKRGASVVSMSFGGNEFSSETGFDGHFNVP----------------GVTFVASSGDSGT--- NLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGV ++PA S +V + GG+TL + + N E W G SGGG+S + P -----------GTEYPAASRYVVSVGGTTL------SSDTAGNYIGEAAWSG---------------------------SGGGVSNVEAEP--------- NTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSK-----NSGWELMGGTSAVAPQFAAMAAVMNSDRS----QRMGLWNPQLYALA G + P + G R PDV +A+P +G+ +Y +GW +GGTSA APQ++A+ A+ NS R+ + + LY + -----------AGQTAWPIPVAG---KRGVPDVSYDANPSSGFAVYDSVTYQGQAGWFQVGGTSAGAPQWSALVAIANSLRTAAGKKSLSGTYDTLYTVG QTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT +T + +NGN + Y+ GLG+ KTAYGSDFHDVTTGSNGNCGSICNAAGGYDYVTGLGS
Show aligned area	111220265	Frankia alni ACN14a	Serine-carboxyl peptidase	544	2e-06	0.27	0.39
IRVKGHVATINKAFAVNLKTARYHGKKIQFSKQAPRLPKQVAQPIRAVVGVTNLMIAKSLTTKSPAQVKHLTAKRSPTKFLKQYHASNLATSGQQGAGQT +R++G A AF L G+ I+ + LP ++ + AV+G+ A+ + + + LTA L+ A + + G GQT VRLRGPAAAARTAFDTPLALYDSGGRAIRGREGDLGLPDELDDRVVAVLGLDERPAARPRFQPAASARQGLTA-------LQVARAYDFPAA--TGEGQT VGIISFGH-VPTAAIKHFWRQAGVPTTGRLETKTTGGATVMD-NGDDSDDETALDAEQAGTIAPRAKVRVYTAKFSDIGWL-DAFTTAFAENRASSLSLS + II G A + ++ +PT G A V + D +D E LD E AG +AP A VY A +D G+L A A R +++S+S IAIIELGGGFGQADLDTYFGGLDLPTPAVSAVGVQGAANVPGGDPDGADGEVLLDIEVAGAVAPGAAQVVYFAPNTDAGFLAAINAAAAATPRPAAISIS WGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERT WG E+ T + A GI+ A+GD GA A + ADFPA SP V A GG+ L + A E WGGPESS---------WTAQAMRAYDQAFAAARAAGITVLAAAGDAGA-------DDATDRLVADFPAGSPNVIACGGTKLTLDAAGARA------SEVV WGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKN W E +A+GGG S + P +Q G +Y R PD+ NADP TGY + WN----------------------EAADSATGGGYSATFTRPAWQPAAVG-------RY-------------------RGLPDISGNADPQTGYRVVVDG SGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGKVYNQAAGLGT ++GGTSAVAP A + A + +Q G L A+A + + FT + A N G Y + G ++ A+GLG+ QP-TVVGGTSAVAPLLAGLVARL----AQLTGAPVADLAAVAYANPAAFTDITAGDNQG---YPARSG--WDPASGLGS
Show aligned area	170780711	Clavibacter michiganensis subsp. sepedonicus	putative peptidase	638	2e-06	0.25	0.39
DETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAY- +E LD + +AP A V + A L AE +SLS+G E + +R+ ++N +L + A + +S F ++G+ G Y EEQHLDVQAVHAMAPDATVSYWGADDCTSTSLYTRILDAAEEGPDVISLSFGGMEGLDTADDRE---------LLNRVLVEAASRDVSVFASTGNDGDYS -----GQNLSESSAMPGIEADFPADSPWVTATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPILLEELTAASGGGI-SRLYGTPK G N + +S PA SP+VTA G ++ + + G I + + +F ++ L+ A GG S Y P GFGDHGGNATVAS---------PASSPYVTAVGATSTGLAED----------------GSIAVEAGWETETRFARNGALIPPGFAFGAGGGQSAEYARPS YQQGVAGVNTYNARKYLTAVGPKSGPKLIHGYRSGRNYPDVVANADPITGYDIYSKNSG---WELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYA +Q V HG +GR PDV + DP TG+ Y + G + GGTS P A+M A+ + +R GL +P +YA WQADRLSV---------------------HG--TGRLLPDVASLGDPNTGFVTYGPHKGRTEYATHGGTSLATPMVASMVAISKAVTGRRFGLASPAIYA LAQT L T LMGT
Show aligned area	163842115	Renibacterium salmoninarum ATCC 33209	peptidase	236	9e-05	0.31	0.48
ETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENR-ASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTGAYG E + D + T AP A + +Y F+ G LD + + + A+ +S S+G N+ L +D + L + Q A +GI + +SGD G EQSFDVDSVHTTAPEANI-LYVGGFNCGGGLDVAMSKILDGKLANIVSNSYG---NVGEALPQDVIEGTL------NIHLQAAGEGIGLYFSSGDNGDQA QNLSESSAMPGIEADFPADSPWVTATGGSTLPIKK L +S DFPA SPWVT+ GG++L + K AKLGYASP------DFPASSPWVTSVGGTSLEVDK
Show aligned area	188574786	Xanthomonas oryzae pv. oryzae PXO99A	proteinase	307	4e-04	0.28	0.39
LDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTG----AYGQNLSESSA---MPGIEADFPADSPWVT L + +N A +S S+G+ E + + + QG QGI+ +SGD A Q L E + +PG+E FPA VT LAGYRQIVQDNEADVVSSSFGVCEKYFTAAYNSGRDATSVAGLFDAVFKQGNAQGITFVTSSGDNAGLECADTQYLVEGNNGRYIPGVE--FPAADAHVT ATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPI----LLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGP- A GG L ++ + G + + PLQ P LL +GGG+S L+ P YQ G T + + L VG +G AVGGGNL-----------FTAYKKDSLGSGYVSESAYADPLQ-ANDPYGVGALLSGGYFGAGGGVSTLFQRPAYQSRPLG-GTRTSMRALPDVGMLAGGC KLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGK I G+ ++ V IY ++L+G TS AP+FA++AA++ + R G N LY LA F R N V GK PAIAGHPCQQDTSSV----------SIYFACFIYKLVG-TSVAAPEFASVAALLGQ-KQGRQGNLNDYLYRLAANGPEAFHRGIPGNNGVVSNDVPIAGK VYNQAAGLGT YN GLGT -YNYTTGLGT
Show aligned area	58583894	Xanthomonas oryzae pv. oryzae KACC10331	proteinase	307	4e-04	0.28	0.39
LDAFTTAFAENRASSLSLSWGLSENILRDLNRDHLLTPLYGDIMNTLLAQGAIQGISTFVASGDTG----AYGQNLSESSA---MPGIEADFPADSPWVT L + +N A +S S+G+ E + + + QG QGI+ +SGD A Q L E + +PG+E FPA VT LAGYRQIVQDNEADVVSSSFGVCEKYFTAAYNSGRDATSVAGLFDAVFKQGNAQGITFVTSSGDNAGLECADTQYLVEGNNGRYIPGVE--FPAADAHVT ATGGSTLPIKKTFAPGISVNVTRERTWGGDIFFKGYHQHPLQFIKHPI----LLEELTAASGGGISRLYGTPKYQQGVAGVNTYNARKYLTAVGPKSGP- A GG L ++ + G + + PLQ P LL +GGG+S L+ P YQ G T + + L VG +G AVGGGNL-----------FTAYKKDSLGSGYVSESAYADPLQ-ANDPYGVGALLSGGYFGAGGGVSTLFQRPAYQSRPLG-GTRTSMRALPDVGMLAGGC KLIHGYRSGRNYPDVVANADPITGYDIYSKNSGWELMGGTSAVAPQFAAMAAVMNSDRSQRMGLWNPQLYALAQTDHSPFTRLDAATNNGNLYYVGQPGK I G+ ++ V IY ++L+G TS AP+FA++AA++ + R G N LY LA F R N V GK PAIAGHPCQQDTSSV----------SIYFACFIYKLVG-TSVAAPEFASVAALLGQ-KQGRQGNLNDYLYRLAANGPEAFHRGIPGNNGVVSNDVPIAGK VYNQAAGLGT YN GLGT -YNYTTGLGT
Show aligned area	48478122	Picrophilus torridus DSM 9790	subtilase family protein	1386	5e-04	0.28	0.43
GAGQTVGIISFGHVPTAAIKHFWRQA---GVPTTGRLETKTTGGATVMDNGDDS-DDETALDAEQAGTIAPRAKVRVYTAKFSDIGWLDAFTTAFAENRA G G TV +I G +P + ++ F +Q T RL GA + D ETALD E +AP A + + D D A++ GQGITVAVIEVGDLPMSWLQEFAKQVWNNSNQVTSRLSVINLLGANLFDGYIYGWTLETALDIEYIAAMAPDAHIDLVAVPNPDFSSFDYAYQYIADHLT S--SLSLSWGLSENILRDLNRDHLLT-----PLYGDIMNTLLAQGAIQGISTFVASGDTGAYGQNLSESSAMPGIEADFPADSPWVTATGGSTL S + + S ++ N D + T P+Y + +TLL++ G++ F ASGD G+Y +L E A A PA + T+ GG L SGNNATDSVTITSN---SYGADEITTALKGAPMYITVEDTLLSELNAVGVTNFFASGDYGSYA-SLCEYGAT---SAGMPAIATGSTSVGGGQL